Detailed information NTG0401305

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HUK75_RS02340
• Genome accession: NZ_CP054792
• Coordinates: 514323..517121 (+)
• Length: 932 a.a.
• NCBI ID: WP_003084722.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain SE5431
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 509323..522121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUK75_RS02320 (HUK75_02320)	dbpA	509804..511180 (-)	1377	WP_033989221.1	ATP-dependent RNA helicase DbpA	-
HUK75_RS02325 (HUK75_02325)	-	511528..511737 (+)	210	WP_003084710.1	cold-shock protein	-
HUK75_RS02330 (HUK75_02330)	-	511888..512412 (+)	525	WP_003084714.1	ATP-dependent zinc protease	-
HUK75_RS02335 (HUK75_02335)	mdtD	512515..513948 (-)	1434	WP_003084717.1	multidrug transporter subunit MdtD	-
HUK75_RS02340 (HUK75_02340)	clpC	514323..517121 (+)	2799	WP_003084722.1	AAA family protein disaggregase ClpG	Regulator
HUK75_RS02345 (HUK75_02345)	-	517223..517801 (+)	579	WP_003084725.1	DUF2780 domain-containing protein	-
HUK75_RS02350 (HUK75_02350)	-	517878..518765 (-)	888	WP_003084727.1	acyltransferase	-
HUK75_RS02355 (HUK75_02355)	-	518908..519417 (+)	510	WP_003084733.1	ATP-dependent zinc protease	-
HUK75_RS02360 (HUK75_02360)	creB	519502..520191 (+)	690	WP_003084734.1	two-component system response regulator CreB	-
HUK75_RS02365 (HUK75_02365)	creC	520191..521615 (+)	1425	WP_033989222.1	two-component system sensor histidine kinase CreC	-

Sequence

Protein

• Length: 932 a.a.
• Molecular weight: 103409.94 Da
• Isoelectric Point: 6.8717

>NTDB_id=401305 HUK75_RS02340 WP_003084722.1 514323..517121(+) (clpC) [Pseudomonas aeruginosa strain SE5431]
MAQELCAICHERPAVARVSLVQNGQRRELALCELHYRQLMRQQRMRSPLESLFGGGSPFDEIFSGFGEQSPVTPVRAREP
EAVDIAEYFSKQTTEYLQRAAQVAAEFGKREVDTEHLLYALADADVVQAVLKQFGLSPADLKQYIEANAVRGASKGEASE
DMTISPRVKSALQHAFALSRELGHSYVGPEHLLLGLAAVPDSFAGTLLKKYGLTEQALRQKAVKVVGKGAEDGRVDGPSN
TPQLDKFSRDLTRLAREGKLDPVIGRSKEVETTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRMVQGEVPEVLRDKRL
VELNINAMVAGAKYRGEFEERLKQVMDELQAAQSEIILFIDEVHTIVGAGQGGGEGGLDVANVLKPAMARGEMNLIGATT
LNEYQKYIEKDAALERRFQPVFVPEPTVEQTISILRGLRDKLEGHHKVTIRDEAFVAAAELSDRYIGNRFLPDKAIDLID
QAAARVRIASTSRPAEIQELEAELAQLKREQDYAASRKWYDEAKVFEKRIQERKEHLEQITERWQQTQGSKTEEVRVEDI
AEIISKLTGIPVTELTAEEREKLLQMEERLHQRVIGQQEAITAVSDAVRLARAGLRQGSRPIATFLFLGPTGVGKTELAK
ALAEVVFGDEDAMIRIDMSEYMERHAVSRLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHADVNNILLQVFDD
GRLTDGKGRVVDFTNTIIIATSNLGSELIMKNAQAGEFAQPPEKLKRELMTTLRGHFRPEFLNRLDEVIVFESLSKAQIE
DIVRLQLERVKRAAHAQDIYLHIDDSLVGHLAEEAYQPEFGARELKRQIRQQLETRLATAMLKGEVKEGETVTFFYDAKD
GVGYRKGAAPKPAARKKSGAGETPRGRATAARKPAAKKGAAAKGKADKPKAK

Nucleotide

• Length: 2799 bp

>NTDB_id=401305 HUK75_RS02340 WP_003084722.1 514323..517121(+) (clpC) [Pseudomonas aeruginosa strain SE5431]
ATGGCCCAGGAACTTTGCGCTATCTGCCACGAACGTCCCGCCGTCGCCCGCGTCAGCCTGGTACAGAACGGCCAGCGCCG
CGAACTCGCCCTCTGCGAACTGCATTACCGCCAGTTGATGCGCCAGCAGCGCATGCGCTCGCCGCTGGAGTCGCTGTTCG
GCGGCGGCAGCCCGTTCGACGAGATCTTCTCCGGCTTCGGCGAGCAGAGCCCGGTCACCCCGGTGCGCGCCCGCGAGCCG
GAGGCGGTGGACATCGCCGAGTACTTCAGCAAGCAGACCACCGAGTACCTGCAACGCGCCGCGCAGGTCGCCGCCGAATT
CGGCAAGCGCGAAGTGGACACCGAGCACCTGCTCTACGCCCTGGCCGACGCCGACGTGGTGCAGGCGGTGCTCAAGCAGT
TCGGCCTGTCGCCGGCCGACCTCAAGCAGTACATCGAGGCCAACGCCGTGCGCGGCGCCAGCAAGGGCGAGGCGAGCGAG
GACATGACCATCTCGCCACGGGTGAAGAGCGCCTTGCAGCATGCCTTCGCCCTGTCCCGCGAACTCGGCCACAGCTATGT
CGGCCCCGAGCACCTGTTGCTCGGCCTGGCGGCGGTGCCGGACAGCTTCGCCGGGACGCTCCTGAAGAAGTACGGCCTGA
CCGAGCAGGCGCTACGGCAGAAAGCGGTCAAGGTGGTCGGCAAGGGCGCCGAGGACGGCCGCGTGGACGGCCCGAGCAAC
ACTCCGCAACTGGACAAGTTCAGCCGCGACCTGACCCGGCTGGCCCGCGAAGGCAAGCTCGATCCGGTGATCGGCCGCTC
GAAGGAAGTCGAGACCACCATCGAGGTGCTCGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCG
GCAAGACCGCCATCGTCGAAGGCCTGGCCCAGCGCATGGTCCAGGGCGAGGTGCCGGAGGTGCTGCGCGACAAGCGCCTG
GTCGAACTGAACATCAACGCCATGGTCGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGCCTCAAGCAGGTGATGGA
CGAACTGCAGGCGGCGCAGAGCGAGATCATCCTGTTCATCGACGAGGTGCACACCATCGTCGGTGCCGGCCAGGGCGGCG
GCGAAGGCGGGCTGGACGTGGCCAACGTGCTGAAGCCGGCGATGGCGCGCGGCGAGATGAACCTGATCGGCGCCACCACC
CTCAACGAGTACCAGAAGTACATCGAGAAGGACGCCGCGCTGGAGCGGCGCTTCCAGCCGGTGTTCGTCCCCGAGCCGAC
GGTGGAGCAGACCATCTCCATCCTCCGTGGCCTGCGCGACAAGCTCGAAGGCCACCACAAGGTGACCATCCGCGACGAGG
CCTTCGTCGCCGCCGCCGAGCTGTCCGACCGCTACATCGGCAACCGCTTCCTGCCGGACAAGGCCATCGACCTGATCGAC
CAGGCCGCCGCCCGCGTGCGCATCGCCAGCACCTCGCGGCCGGCCGAGATCCAGGAACTGGAGGCCGAGCTGGCGCAGCT
CAAGCGCGAGCAGGACTACGCCGCCAGCCGCAAGTGGTACGACGAGGCGAAGGTCTTCGAGAAACGCATCCAGGAACGCA
AGGAACACCTCGAGCAGATCACCGAGCGCTGGCAGCAGACCCAGGGGTCGAAGACCGAGGAGGTGCGGGTCGAGGACATC
GCCGAGATCATCTCCAAGCTCACCGGCATCCCGGTCACCGAACTGACCGCCGAGGAGCGCGAGAAGCTCCTGCAGATGGA
AGAGCGCCTGCACCAGCGGGTGATAGGCCAGCAGGAAGCGATCACCGCGGTCAGCGACGCCGTGCGCCTGGCCCGCGCCG
GGCTGCGCCAGGGCAGCCGGCCGATCGCCACCTTCCTGTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGCTGGCCAAG
GCCCTGGCCGAGGTGGTGTTCGGCGACGAAGACGCGATGATCCGCATCGACATGAGCGAATACATGGAGCGCCACGCGGT
GTCCCGGCTGATCGGTGCGCCGCCGGGCTACGTCGGCTACGACGAGGGCGGCCAGCTCACCGAGCGGGTGCGCCGGCGGC
CGTACAGCGTGATCCTGCTCGACGAGATCGAGAAGGCCCACGCCGACGTCAACAACATCCTCCTGCAGGTGTTCGACGAC
GGCCGCCTGACCGACGGCAAGGGGCGCGTGGTGGACTTCACCAACACCATCATCATCGCCACCAGCAACCTCGGCTCCGA
GCTGATCATGAAGAACGCCCAGGCCGGCGAGTTCGCCCAGCCGCCGGAGAAGCTCAAGCGCGAACTGATGACTACCCTGC
GCGGGCATTTCCGCCCGGAATTCCTCAACCGCCTCGACGAGGTGATCGTCTTCGAATCGTTGAGCAAGGCGCAGATCGAG
GACATCGTGCGCCTGCAACTGGAGCGGGTGAAGCGCGCCGCGCACGCCCAGGACATCTACCTGCACATCGACGACAGCCT
GGTCGGCCACCTCGCCGAAGAGGCCTACCAGCCGGAGTTCGGCGCCCGCGAACTGAAGCGGCAGATCCGCCAGCAGCTGG
AGACGCGCCTGGCCACGGCGATGCTCAAGGGCGAGGTGAAGGAGGGCGAGACGGTCACCTTCTTCTACGACGCCAAGGAC
GGCGTCGGCTACCGCAAGGGCGCCGCGCCGAAGCCGGCGGCACGCAAGAAGTCCGGTGCCGGCGAGACGCCCAGGGGCCG
CGCGACGGCGGCGAGGAAGCCGGCGGCGAAGAAAGGCGCCGCCGCCAAGGGCAAGGCCGACAAGCCGAAGGCCAAGTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (427-524)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (100-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (175-226)

• AAA domain (Cdc48 subfamily) (AAA_2) (620-788)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (794-873)

• ATPase family associated with various cellular activities (AAA) (AAA) (286-419)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	86.052	0.433
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.113	85.622	0.386
clpC	Streptococcus thermophilus LMD-9	42.684	88.734	0.379
clpC	Streptococcus thermophilus LMG 18311	42.443	88.734	0.377
clpC	Streptococcus mutans UA159	41.505	88.412	0.367