Detailed information NTG0400516

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: GJS33_RS02955
• Genome accession: NZ_CP046041
• Coordinates: 613859..616114 (-)
• Length: 751 a.a.
• NCBI ID: WP_043052867.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain AZ-45470
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 608859..621114

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS33_RS02940 (GJS33_02940)	ileS	609453..612251 (+)	2799	WP_154298767.1	isoleucine--tRNA ligase	-
GJS33_RS02945 (GJS33_02945)	-	612902..613204 (-)	303	WP_012515246.1	DUF1827 family protein	-
GJS33_RS02950 (GJS33_02950)	-	613266..613712 (-)	447	WP_154298769.1	NUDIX hydrolase	-
GJS33_RS02955 (GJS33_02955)	clpE	613859..616114 (-)	2256	WP_043052867.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GJS33_RS02960 (GJS33_02960)	-	616396..616626 (+)	231	WP_012515249.1	DUF1797 family protein	-
GJS33_RS02965 (GJS33_02965)	-	617071..618144 (-)	1074	WP_154298771.1	LPXTG cell wall anchor domain-containing protein	-
GJS33_RS02970 (GJS33_02970)	-	618500..619183 (+)	684	WP_154298773.1	amino acid ABC transporter permease	-
GJS33_RS02975 (GJS33_02975)	-	619185..619922 (+)	738	WP_042670303.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83873.29 Da
• Isoelectric Point: 5.8561

>NTDB_id=400516 GJS33_RS02955 WP_043052867.1 613859..616114(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYTGNQKAQQQSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNHTQPAQETNKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDTPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFKPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPAEKDLRAVLTSNGHIIIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=400516 GJS33_RS02955 WP_043052867.1 613859..616114(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGCTTTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAACGGAAAGCAAAGGCAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCCTGGGAGGCTATACTGGCAATCAAAAGG
CCCAGCAGCAGTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTGAACAATTTTAGAGCCTTCGGTCAGCTTCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTACCGTCCCAATCACACACAGCCAGC
ACAAGAGACTAACAAAGGTTTGCTTGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGATCCTG
TCATCGGACGTGACGATGAGATTATCCGCGTGATCGAGATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGA
GAACCAGGTGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGTGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAGGAAATCCGCAAGCGCCATGACGTTATCCTTTTTATTGATGAAATCCATGAAATTGTGGGAGCCGGG
GCAGTTGGTGATGGCAGTATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
CACCACTCTCAATGAATACCGCATTATCGAAAAGGACGCAGCCCTCGAACGACGCATGCAGCCGGTTAAGGTAGATGAGC
CCTCGGTTGAAGAAACAATCACGATCCTAAAAGGAATCCAAGCCAAATACGAGGACTATCACCATGTCAAATATAGCCAG
TCGGCTATTGAAGCAGCTGCTAACCTCTCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTACT
AGATGAGGCTGGCTCAAAAATGAACCTAACCCTTAACTTTGTTGACCCAAAAGACATCGACAAGCGTTTGATTGAGGCAG
AAAACCTTAAGGCACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTACTTCCGCGATCAAATCGCCAAATACAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATACTCCAATCATTACCGATAAGACCATCGAAGCAATCGTTGAGCAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCTGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGACGCCGTTGATAAAATTGCTAAGGCTATCCGTCGTAATCGTGTTGGACTTGGAGCGCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGACCAACCGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCCATTGAGCTTTT
TGGCTCTGCTGATAACATGATTCGCTTTGACATGTCTGAATACATGGAAAAGCATGCTGTGGCTAAGCTTGTCGGTGCCC
CTCCAGGCTACGTTGGCTATGAGGAGGCAGGGCAGTTAACAGAGCAGGTACGTCGCAACCCTTACTCGCTCATTTTGTTA
GATGAGATTGAAAAGGCTCACCCTGATGTGATGCACATGTTTTTACAGGTCCTAGATGACGGACGATTAACCGACGGACA
AGGACGGACCGTTAGCTTTAAGGATACTATTATCATCATGACATCAAATGCCGGCACCGGCAAAACAGAAGCTTCAGTAG
GCTTTGGCGCTGCTAGAGAAGGGCGGACAAATTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGTCCCGAGTTCATGAAC
CGTTTTGATGGCATTATTGAGTTTAAGCCACTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGT
TAATCACCGCCTTGCTCACAATAACATTCGCCTTGATGTCACCCAAAAGGTCAAAGAAAAGCTCGTTGAGCTAGGCTATG
ATCCTAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGACTACATTGAGGATGCCATTACCGACTTCTACCTTGAG
CACCCAGCAGAAAAAGACCTGCGAGCTGTCCTGACCTCTAATGGACACATTATAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-725)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

• AAA lid domain (AAA_lid_9) (295-392)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.543	99.068	0.838
clpE	Streptococcus pneumoniae Rx1	82.869	100	0.831
clpE	Streptococcus pneumoniae D39	82.869	100	0.831
clpE	Streptococcus pneumoniae R6	82.869	100	0.831
clpE	Streptococcus pneumoniae TIGR4	82.736	100	0.83
clpC	Lactococcus lactis subsp. cremoris KW2	75.399	100	0.755
clpC	Bacillus subtilis subsp. subtilis str. 168	49.926	90.146	0.45
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.729	85.486	0.399
clpC	Streptococcus pneumoniae Rx1	48.065	82.557	0.397
clpC	Streptococcus pneumoniae D39	48.065	82.557	0.397
clpC	Streptococcus pneumoniae TIGR4	47.903	82.557	0.395
clpC	Streptococcus mutans UA159	47.343	82.69	0.391
clpC	Streptococcus thermophilus LMD-9	46.508	83.888	0.39
clpC	Streptococcus thermophilus LMG 18311	46.19	83.888	0.387