Detailed information NTG0400515

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: GJS33_RS02840
• Genome accession: NZ_CP046041
• Coordinates: 589634..590671 (+)
• Length: 345 a.a.
• NCBI ID: WP_014622492.1
• Uniprot ID: A0A6D2LSH8
• Organism: Streptococcus equi subsp. zooepidemicus strain AZ-45470
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 584634..595671

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS33_RS02815 (GJS33_02815)	-	584947..586278 (+)	1332	WP_043025442.1	dipeptidase	-
GJS33_RS02820 (GJS33_02820)	arcC	586296..587246 (+)	951	WP_111689942.1	carbamate kinase	-
GJS33_RS02825 (GJS33_02825)	asnA	587466..588458 (+)	993	WP_012515219.1	aspartate--ammonia ligase	-
GJS33_RS02830 (GJS33_02830)	rsmD	588627..589166 (+)	540	WP_111692279.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
GJS33_RS02835 (GJS33_02835)	coaD	589156..589656 (+)	501	WP_111692280.1	pantetheine-phosphate adenylyltransferase	-
GJS33_RS02840 (GJS33_02840)	sepM	589634..590671 (+)	1038	WP_014622492.1	SepM family pheromone-processing serine protease	Regulator
GJS33_RS02845 (GJS33_02845)	-	591291..591905 (+)	615	WP_111692281.1	YutD family protein	-
GJS33_RS02850 (GJS33_02850)	rlmN	591909..592991 (+)	1083	WP_043029472.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
GJS33_RS02855 (GJS33_02855)	-	593414..593863 (-)	450	WP_228269161.1	peptidase	-
GJS33_RS02860 (GJS33_02860)	-	594263..594793 (+)	531	WP_012515230.1	Dps family protein	-
GJS33_RS02865 (GJS33_02865)	-	595167..595400 (+)	234	WP_012515231.1	YqgQ family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37450.05 Da
• Isoelectric Point: 9.2833

>NTDB_id=400515 GJS33_RS02840 WP_014622492.1 589634..590671(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MKTIKKFKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVDKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=400515 GJS33_RS02840 WP_014622492.1 589634..590671(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGAAAACAATAAAAAAATTTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTAGTGAGCCTCAGTCGGGCCACCTTGGCTAAATTGCTCTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGACTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTATCAGGCCCTTACTCTAGCAGGCAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCCGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACCGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGGATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTACCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: A0A6D2LSH8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.145	100	0.701