Detailed information NTG0400465

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: GJS32_RS05155
• Genome accession: NZ_CP046040
• Coordinates: 1076065..1076802 (+)
• Length: 245 a.a.
• NCBI ID: WP_014622844.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain OH-71905
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1071065..1081802

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS32_RS05125 (GJS32_05125)	-	1071510..1072415 (-)	906	WP_012677986.1	diacylglycerol/lipid kinase family protein	-
GJS32_RS05130 (GJS32_05130)	trhA	1072525..1073175 (-)	651	WP_012515586.1	PAQR family membrane homeostasis protein TrhA	-
GJS32_RS05135 (GJS32_05135)	-	1073159..1073614 (-)	456	WP_014622841.1	DUF1836 domain-containing protein	-
GJS32_RS05140 (GJS32_05140)	-	1073874..1074629 (+)	756	WP_014622842.1	class I SAM-dependent methyltransferase	-
GJS32_RS05145 (GJS32_05145)	-	1074657..1074995 (+)	339	WP_014622843.1	cupin domain-containing protein	-
GJS32_RS05150 (GJS32_05150)	-	1074997..1075302 (+)	306	WP_012677981.1	AraC family ligand binding domain-containing protein	-
GJS32_RS05155 (GJS32_05155)	comE/blpR	1076065..1076802 (+)	738	WP_014622844.1	response regulator transcription factor	Regulator
GJS32_RS05160 (GJS32_05160)	-	1077175..1077375 (+)	201	WP_012679509.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
GJS32_RS05165 (GJS32_05165)	-	1077442..1078296 (+)	855	WP_012515593.1	ABC transporter ATP-binding protein	-
GJS32_RS05170 (GJS32_05170)	-	1078302..1079465 (+)	1164	WP_014622845.1	ABC transporter permease subunit	-
GJS32_RS05175 (GJS32_05175)	-	1079727..1079957 (+)	231	WP_012515596.1	Blp family class II bacteriocin	-
GJS32_RS05185 (GJS32_05185)	-	1080827..1081108 (+)	282	WP_080004977.1	lactococcin 972 family bacteriocin	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28903.28 Da
• Isoelectric Point: 8.2679

>NTDB_id=400465 GJS32_RS05155 WP_014622844.1 1076065..1076802(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
MNIFILEDDLGQQFRLQMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHRLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKLKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=400465 GJS32_RS05155 WP_014622844.1 1076065..1076802(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTCAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATTGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAGGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAACGGGCAGTCTTGCATGGTTTCAAGACTAAAACTGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (16-122)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.306	98.776	0.527
comE/comE1	Streptococcus equinus JB1	45.455	98.776	0.449
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367