Detailed information NTG0400454

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: GJS32_RS02840
• Genome accession: NZ_CP046040
• Coordinates: 585281..586318 (+)
• Length: 345 a.a.
• NCBI ID: WP_014622492.1
• Uniprot ID: A0A6D2LSH8
• Organism: Streptococcus equi subsp. zooepidemicus strain OH-71905
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 580281..591318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS32_RS02815 (GJS32_02815)	-	580594..581925 (+)	1332	WP_014622489.1	dipeptidase	-
GJS32_RS02820 (GJS32_02820)	arcC	581943..582893 (+)	951	WP_012515218.1	carbamate kinase	-
GJS32_RS02825 (GJS32_02825)	asnA	583112..584104 (+)	993	WP_012515219.1	aspartate--ammonia ligase	-
GJS32_RS02830 (GJS32_02830)	rsmD	584274..584813 (+)	540	WP_014622490.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
GJS32_RS02835 (GJS32_02835)	coaD	584803..585303 (+)	501	WP_014622491.1	pantetheine-phosphate adenylyltransferase	-
GJS32_RS02840 (GJS32_02840)	sepM	585281..586318 (+)	1038	WP_014622492.1	SepM family pheromone-processing serine protease	Regulator
GJS32_RS02845 (GJS32_02845)	-	586918..587532 (+)	615	WP_014622493.1	YutD family protein	-
GJS32_RS02850 (GJS32_02850)	rlmN	587536..588618 (+)	1083	WP_014622494.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
GJS32_RS02855 (GJS32_02855)	-	589051..589548 (-)	498	WP_228269612.1	peptidase	-
GJS32_RS02860 (GJS32_02860)	-	589900..590430 (+)	531	WP_014622497.1	Dps family protein	-
GJS32_RS02865 (GJS32_02865)	-	590806..591039 (+)	234	WP_012515231.1	YqgQ family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37450.05 Da
• Isoelectric Point: 9.2833

>NTDB_id=400454 GJS32_RS02840 WP_014622492.1 585281..586318(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
MKTIKKFKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVDKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=400454 GJS32_RS02840 WP_014622492.1 585281..586318(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
ATGAAAACAATAAAAAAATTTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTGGTGAGCCTCAGTCGGGCTACCTTGGCTAAATTGCTCTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGATTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTACCAGGCCCTTACTCTAGCAGGTAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCGGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACCGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGGATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTACCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: A0A6D2LSH8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.145	100	0.701