Detailed information NTG0400090

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: GJS30_RS17925
• Genome accession: NZ_CP045993
• Coordinates: 3674034..3675197 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain LABIM22
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3669034..3680197

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS30_RS17895 (GJS30_17835)	-	3669299..3669718 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
GJS30_RS17900 (GJS30_17840)	comFC	3669792..3670481 (-)	690	WP_199449054.1	ComF family protein	Machinery gene
GJS30_RS17905 (GJS30_17845)	-	3670487..3670771 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
GJS30_RS17910 (GJS30_17850)	comFA	3670829..3672214 (-)	1386	WP_029972824.1	DEAD/DEAH box helicase	Machinery gene
GJS30_RS17915 (GJS30_17855)	-	3672322..3673170 (-)	849	WP_003151387.1	DegV family protein	-
GJS30_RS17920 (GJS30_17860)	degU	3673268..3673957 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
GJS30_RS17925 (GJS30_17865)	degS	3674034..3675197 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
GJS30_RS17930 (GJS30_17870)	-	3675420..3676067 (+)	648	WP_007614107.1	YigZ family protein	-
GJS30_RS17935 (GJS30_17875)	-	3676072..3677286 (+)	1215	WP_103526592.1	LCP family protein	-
GJS30_RS17940 (GJS30_17880)	-	3677385..3678461 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
GJS30_RS17945 (GJS30_17885)	-	3678594..3679790 (-)	1197	WP_060673980.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=400090 GJS30_RS17925 WP_007407484.1 3674034..3675197(-) (degS) [Bacillus velezensis strain LABIM22]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=400090 GJS30_RS17925 WP_007407484.1 3674034..3675197(-) (degS) [Bacillus velezensis strain LABIM22]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951