Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GI367_RS01945 Genome accession   NZ_CP045926
Coordinates   377854..378510 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain AL7     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 372854..383510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GI367_RS01920 (GI367_01920) oppF 373384..374301 (+) 918 WP_007610608.1 oligopeptide ABC transporter ATP-binding protein OppF -
  GI367_RS01925 (GI367_01925) - 374408..375595 (+) 1188 WP_029325948.1 putative glycoside hydrolase -
  GI367_RS01930 (GI367_01930) - 375713..376291 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  GI367_RS01935 (GI367_01935) spx 376470..376865 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  GI367_RS01940 (GI367_01940) - 376922..377578 (-) 657 WP_007610610.1 TerC family protein -
  GI367_RS19060 - 377761..377871 (+) 111 Protein_372 adaptor protein MecA -
  GI367_RS01945 (GI367_01945) mecA 377854..378510 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  GI367_RS01950 (GI367_01950) - 378661..379821 (+) 1161 WP_007610612.1 competence protein CoiA family protein -
  GI367_RS01955 (GI367_01955) pepF 380049..381878 (+) 1830 WP_139325667.1 oligoendopeptidase F Regulator
  GI367_RS19065 - 381916..382083 (-) 168 WP_003155026.1 hypothetical protein -
  GI367_RS01960 (GI367_01960) spxH 382369..383271 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=399231 GI367_RS01945 WP_003155032.1 377854..378510(+) (mecA) [Bacillus velezensis strain AL7]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=399231 GI367_RS01945 WP_003155032.1 377854..378510(+) (mecA) [Bacillus velezensis strain AL7]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment