Detailed information NTG0398837

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB466_RS09585
• Genome accession: NZ_CP045866
• Coordinates: 1904683..1905570 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CFSAN007894
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1899683..1910570

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB466_RS09555 (GIX97_09585)	-	1899702..1899794 (+)	93	WP_010956583.1	hypothetical protein	-
AB466_RS09560 (GIX97_09590)	-	1899902..1900399 (-)	498	WP_031900639.1	glutathione peroxidase	-
AB466_RS09565 (GIX97_09595)	-	1900409..1900669 (-)	261	WP_001791974.1	hypothetical protein	-
AB466_RS09570 (GIX97_09600)	-	1901051..1901164 (-)	114	Protein_1866	hypothetical protein	-
AB466_RS09575 (GIX97_09605)	-	1901823..1903823 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB466_RS09580 (GIX97_09610)	-	1903820..1904575 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB466_RS09585 (GIX97_09615)	braS	1904683..1905570 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB466_RS09590 (GIX97_09620)	braR	1905581..1906246 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB466_RS09595 (GIX97_09625)	-	1906272..1906472 (-)	201	WP_000604730.1	hypothetical protein	-
AB466_RS09600 (GIX97_09630)	-	1906670..1908094 (+)	1425	WP_000953755.1	alkaline phosphatase	-
AB466_RS09605 (GIX97_RS13620)	-	1908164..1908274 (+)	111	Protein_1873	hypothetical protein	-
AB466_RS09610 (GIX97_09640)	-	1908377..1908832 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB466_RS09615 (GIX97_09645)	-	1909077..1909838 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=398837 AB466_RS09585 WP_000143425.1 1904683..1905570(-) (braS) [Staphylococcus aureus strain CFSAN007894]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=398837 AB466_RS09585 WP_000143425.1 1904683..1905570(-) (braS) [Staphylococcus aureus strain CFSAN007894]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1