Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GII77_RS06485 Genome accession   NZ_CP045825
Coordinates   1241738..1242394 (+) Length   218 a.a.
NCBI ID   WP_015252354.1    Uniprot ID   -
Organism   Bacillus subtilis strain 75     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1236738..1247394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GII77_RS06455 (GII77_06455) oppF 1237203..1238120 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  GII77_RS06460 (GII77_06460) yjbB 1238227..1239444 (+) 1218 WP_080019554.1 MFS transporter -
  GII77_RS06465 (GII77_06465) yjbC 1239608..1240186 (+) 579 WP_003244921.1 GNAT family N-acetyltransferase -
  GII77_RS06470 (GII77_06470) spx 1240367..1240762 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  GII77_RS06475 (GII77_06475) yjbE 1240805..1241461 (-) 657 WP_015252355.1 YjbE family putative metal transport protein -
  GII77_RS06480 (GII77_06480) - 1241631..1241771 (+) 141 WP_119122854.1 hypothetical protein -
  GII77_RS06485 (GII77_06485) mecA 1241738..1242394 (+) 657 WP_015252354.1 adaptor protein MecA Regulator
  GII77_RS06490 (GII77_06490) - 1242389..1242511 (-) 123 WP_003245684.1 hypothetical protein -
  GII77_RS06495 (GII77_06495) coiA 1242555..1243706 (+) 1152 WP_044052564.1 competence protein CoiA Machinery gene
  GII77_RS06500 (GII77_06500) pepF 1243936..1245765 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  GII77_RS06505 (GII77_06505) - 1245803..1245970 (-) 168 WP_003244944.1 hypothetical protein -
  GII77_RS06510 (GII77_06510) spxH 1246284..1247183 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25716.53 Da        Isoelectric Point: 4.0841

>NTDB_id=398288 GII77_RS06485 WP_015252354.1 1241738..1242394(+) (mecA) [Bacillus subtilis strain 75]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFGNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=398288 GII77_RS06485 WP_015252354.1 1241738..1242394(+) (mecA) [Bacillus subtilis strain 75]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTGGCAATATGACTGATGAAGAGGTTGAAAATCAACTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

98.624

100

0.986

Multiple sequence alignment