Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   HQ617_RS09950 Genome accession   NZ_CP054055
Coordinates   1959494..1961467 (-) Length   657 a.a.
NCBI ID   WP_235065594.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS47     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1954494..1966467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HQ617_RS09925 (HQ617_09880) recA 1954503..1955642 (-) 1140 WP_001085741.1 recombinase RecA Machinery gene
  HQ617_RS09930 (HQ617_09885) cinA 1955716..1956975 (-) 1260 WP_001200975.1 competence/damage-inducible protein A Machinery gene
  HQ617_RS09935 (HQ617_09890) - 1957064..1957615 (-) 552 WP_000817341.1 DNA-3-methyladenine glycosylase I -
  HQ617_RS09940 (HQ617_09895) ruvA 1957638..1958228 (-) 591 WP_000272490.1 Holliday junction branch migration protein RuvA Machinery gene
  HQ617_RS09945 (HQ617_09900) - 1958230..1959462 (-) 1233 WP_000657472.1 MFS transporter -
  HQ617_RS09950 (HQ617_09905) hexB 1959494..1961467 (-) 1974 WP_235065594.1 DNA mismatch repair endonuclease MutL Machinery gene
  HQ617_RS09955 (HQ617_09910) - 1961693..1961896 (+) 204 WP_000191849.1 cold-shock protein -
  HQ617_RS09960 (HQ617_09915) hexA 1961953..1964529 (-) 2577 WP_001118379.1 DNA mismatch repair protein MutS Machinery gene
  HQ617_RS09965 (HQ617_09920) argR 1964586..1965023 (-) 438 WP_001033152.1 arginine repressor -

Sequence

Protein


Download         Length: 657 a.a.        Molecular weight: 73832.97 Da        Isoelectric Point: 5.3704

>NTDB_id=397466 HQ617_RS09950 WP_235065594.1 1959494..1961467(-) (hexB) [Streptococcus agalactiae strain GBS47]
MSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARLKY
MKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVSLP
ELTRANRNYITLLINARYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLISS
AISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQPGLYYDRTKNDFFIDADTVSEPIANFTNLDKSDGSVDNDVK
NSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYIID
QHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEEVE
SGVYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADMEKM
FKRIQENHTSLRDLGKY

Nucleotide


Download         Length: 1974 bp        

>NTDB_id=397466 HQ617_RS09950 WP_235065594.1 1959494..1961467(-) (hexB) [Streptococcus agalactiae strain GBS47]
TTGTCTAAAATTATTGAATTACCGGATATATTAGCTAACCAGATTGCTGCTGGTGAGGTTGTTGAAAGACCTAGTAGCGT
CGTTAAAGAATTAGTTGAAAATGCCATAGATGCAGGAAGTAGCCAAATTACCATAGAGGTTGAAGAATCTGGTCTTAAAA
AGATTCAAATAACGGATAACGGTGAAGGGATGACTAGTGAGGATGCTGTTCTCAGTTTACGACGTCACGCTACATCCAAA
ATCAAAAGCCAGAGTGACCTTTTTCGTATTCGGACCTTAGGTTTTCGTGGTGAAGCCCTACCATCAATCGCTTCGATTAG
TTTAATGACGATAAAAACAGCTACAGAGCAAGGGAAACAAGGGACGTTACTTGTTGCTAAAGGGGGAAACATTGAAAAAC
AGGAAGTTGTTTCAAGTCCTCGTGGAACAAAAATTTTAGTTGAAAATTTATTCTTTAATACGCCTGCCAGATTGAAATAC
ATGAAGAGTTTACAGTCTGAACTAGCTCATATTATTGATATTGTTAATAGACTCAGTCTAGCGCATCCGGAAGTTGCTTT
TACACTGATAAATGATGGTAAAGAAATGACTAAAACTAGTGGGACTGGCGATTTGAGACAGGCGATTGCAGGTATTTATG
GTTTAAATACTGCAAAAAAAATGATTGAGATTTCAAATGCAGATTTAGATTTTGAAATTTCGGGTTATGTAAGTTTGCCT
GAATTGACACGAGCTAACCGAAACTATATTACCCTATTAATTAACGCTCGTTACATTAAAAATTTTCTTTTAAACCGCTC
AATTCTAGATGGTTATGGTTCAAAGTTGATGGTTGGAAGATTTCCAATTGCTGTCATTGATATTCAGATAGATCCTTATC
TAGCAGATGTCAACGTTCATCCGACTAAGCAAGAGGTGAGAATTTCTAAGGAACGAGAATTAATGAGTTTAATAAGCTCA
GCAATTTCTGAGAGTCTTAAACAATATGATTTGATTCCGGATGCTTTAGAGAATTTAGCTAAAACTAGTACCCGAAGTGT
AGATAAGCCTATACAAACAAGCTTCTCACTAAAACAGCCTGGTTTGTATTACGATAGGACTAAAAATGACTTTTTTATAG
ATGCAGATACTGTATCTGAACCTATTGCTAACTTTACAAACCTTGACAAAAGTGACGGTTCAGTTGACAATGATGTAAAA
AACTCTGTTAATCAAGGAGCAACGCAGTCTCCTAATATAAAGTATGCTAGTAGAGATCAAGCTGATAGTGAGAACTTCAT
TCATTCTCAGGACTACCTTAGTAGTAAACAGTCACTTAACAAACTTGTTGAAAAATTAGATTCGGAAGAAAGTTCGACTT
TTCCAGAGCTCGAATTTTTTGGTCAAATGCATGGGACCTACTTATTTGCTCAAGGGAATGGTGGGTTGTATATTATTGAT
CAACATGCAGCTCAAGAGCGTGTAAAATACGAGTATTACCGTGAAAAGATAGGTGAGGTTGATAATAGTCTTCAACAATT
GTTAGTACCATTTCTATTTGAATTTTCAAGTTCAGATTTTCTTCAATTACAAGAAAAAATGTCATTATTACAAGATGTTG
GTATTTTCTTGGAACCGTATGGTAATAATACTTTCATTTTAAGGGAACATCCAATTTGGATGAAAGAAGAAGAGGTAGAG
TCTGGCGTTTATGAAATGTGTGATATGTTGTTGCTCACTAATGAAGTCTCAGTGAAAAAATATCGCGCAGAGTTGGCTAT
TATGATGTCTTGCAAGCGATCTATTAAAGCAAACCATACGCTAGACGATTACTCAGCACGTCATTTATTAGATCAGTTAG
CGCAATGTAAAAATCCTTATAATTGCCCTCATGGAAGACCTGTTTTAGTTAATTTTACAAAAGCTGATATGGAGAAAATG
TTTAAACGAATCCAAGAAAATCATACAAGCCTCAGGGATTTAGGAAAATATTGA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(458-601)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.892

100

0.691

Multiple sequence alignment