Detailed information NTG0397104

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FOC63_RS03635
• Genome accession: NZ_CP054015
• Coordinates: 745801..748371 (-)
• Length: 856 a.a.
• NCBI ID: WP_009855174.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus strain FDAARGOS_755
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 740801..753371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC63_RS03605 (FOC63_03605)	-	740891..741064 (-)	174	WP_009855168.1	hypothetical protein	-
FOC63_RS03610 (FOC63_03610)	-	741114..741578 (-)	465	WP_009855169.1	hypothetical protein	-
FOC63_RS03615 (FOC63_03615)	-	741648..742055 (-)	408	WP_009855170.1	hypothetical protein	-
FOC63_RS03620 (FOC63_03620)	-	742218..743072 (+)	855	WP_009855171.1	helix-turn-helix domain-containing protein	-
FOC63_RS03625 (FOC63_03625)	ruvA	743146..743739 (-)	594	WP_009855172.1	Holliday junction branch migration protein RuvA	Machinery gene
FOC63_RS03630 (FOC63_03630)	hexB	743741..745684 (-)	1944	WP_009855173.1	DNA mismatch repair endonuclease MutL	Machinery gene
FOC63_RS03635 (FOC63_03635)	hexA	745801..748371 (-)	2571	WP_009855174.1	DNA mismatch repair protein MutS	Machinery gene
FOC63_RS03640 (FOC63_03640)	-	748358..748714 (-)	357	WP_009855175.1	YlbF family regulator	-
FOC63_RS03645 (FOC63_03645)	argR	748711..749148 (-)	438	WP_003066930.1	arginine repressor	-
FOC63_RS03650 (FOC63_03650)	argS	749339..751030 (+)	1692	WP_009855176.1	arginine--tRNA ligase	-
FOC63_RS03655 (FOC63_03655)	-	751143..751436 (+)	294	WP_009855177.1	bacteriocin immunity protein	-
FOC63_RS03660 (FOC63_03660)	-	751477..752982 (-)	1506	WP_009855178.1	prolyl oligopeptidase family serine peptidase	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95896.23 Da
• Isoelectric Point: 4.8516

>NTDB_id=397104 FOC63_RS03635 WP_009855174.1 745801..748371(-) (hexA) [Streptococcus gallolyticus strain FDAARGOS_755]
MTKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFFSTSLSDFTS
LRSEILNLKAREVVVGYELSETEQHSLVKQLNLLLSFEQERYEDVHLIDPDLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQAQIEERQNIVQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPTIKAILESFESPHLDKLVNNIDTLPELESLIRSAIAP
DAPAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRGQVERYITRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFDADINIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVNLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASSQSLILFDELGRGTATYDGMALAQSIIEYIHNHIGAKTMFATHYHEL
TALSTSLTHLINVHVATLEKNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEELLQRADSILTNLESGAAQLQLTPEVEVG
PITVKSEVAEPVAEQLSLFADDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=397104 FOC63_RS03635 WP_009855174.1 745801..748371(-) (hexA) [Streptococcus gallolyticus strain FDAARGOS_755]
ATGACAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGACGTAAAAAAAGATTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTATGAATTATTTTATGATGATGCGGTTAAAGCTGCACAGATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAATCCAATTCCAATGGCAGGTGTGCCTTATCATTCTGCGCAACAATACATTGATGTATTAGTG
GAAATGGGTTACAAGGTGGCAATTGCTGAGCAAATGGAAGACCCAAAACAAGCCGTCGGTGTGGTTAAACGTGAAGTCGT
TCAAGTGATTACGCCAGGAACAGCTGTCGATTCCTCTAAACCAGATAATGCTAACAATTTCTTGGTGGCTATCGATTCTG
ACGGCAAAACGTTTGGGCTAGCCTATATGGACGTGTCAACAGGTGAATTTTTCTCAACAAGTCTTTCTGATTTTACAAGC
CTTAGAAGTGAAATTCTGAACCTTAAAGCGCGTGAAGTTGTTGTTGGTTATGAGCTTTCTGAAACAGAGCAACATAGCTT
AGTCAAACAATTAAATTTACTCTTATCGTTTGAACAAGAACGTTATGAAGATGTGCATTTAATCGACCCAGATTTAACGG
CTTTAGAAATTTCAGCAGCTGAGAAATTGCTACAATACGTTCATACAACGCAAAAACGTGAGCTAAGCCATTTGCAAAAA
TTGGTTCATTATGAAATCAAAGATTACTTGCAAATGTCTTATACGACAAAATCTAGTCTGGATTTATTAGAAAATGCTCG
AACAAGTAAAAAACATGGTAGCCTTTATTGGTTACTAGATGAAACTAAAACGGCTATGGGAATGCGTCTATTGCGCAATT
GGATTGACCGTCCTTTGGTGAACCAAGCACAGATTGAAGAGCGCCAAAATATTGTTCAAGTTTTCCTAGATAATTTCTTT
GAGCGTAGTGATTTGACGGATAGTCTCAAAGGTGTTTATGATATTGAACGTTTAGCGAGTCGTGTGTCATTTGGAAAAGC
TAATCCAAAAGATTTATTACAACTCGGTCATACTTTGGCACAAGTGCCAACGATTAAGGCGATTTTAGAATCGTTTGAGA
GCCCTCACCTTGACAAGCTTGTCAACAACATTGACACTTTGCCAGAGCTAGAATCGCTGATTCGCTCAGCTATTGCCCCA
GATGCCCCTGCTGTTATCACAGAAGGTAGCATTATCCGTACAGGCTTTGATGAGACTTTGGATAAATACCGTAAGGTTAT
GCGCGAGGGGACTAGCTGGATTGCAGAAATTGAAGCTAAGGAACGTGCTGCAAGTGGGATTACCAATCTAAAAATTGATT
ATAATAAAAAAGACGGATACTATTTCCATGTGACAAATTCCAATCTCTCTCTAGTGCCAGATTATTTCTTCCGCAAGGCA
ACGTTGAAAAATTCAGAGCGTTTCGGAACGGCAGAATTGGCAAAAATTGAAGGTGAGATGTTGGAGGCGCGTGAGCAATC
AGCAAGCTTAGAATATGATATTTTCATGCGCGTTCGCGGACAAGTTGAGCGTTACATTACACGTTTGCAAGACTTGGCTA
AGGCGATTTCAACCGTTGACGTTTTACAAAGTTTAGCCGTTGTTGCAGAAAATAATCATTATGTTCGTCCGACGTTCAAC
GATAGCCATGAAATTAAGATTGAAAAAGGTCGTCATGCGGTCGTTGAAAAAGTCATGGGAACGCAAGAATATATTCCTAA
TACGATTACGTTTGATGCCGATATCAACATTCAACTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AACTTGCCTTGACAGTTATTATGGCTCAAATGGGGTCTTACGTAGCTGCTGAAAGTGTCAATTTACCAGTATTTGATGCG
ATTTTCACGCGTATTGGTGCGGCAGATGATTTGATTTCAGGACAGTCAACGTTTATGGTGGAAATGATGGAAGCTAACCA
AGCTATCAAACGTGCAAGTTCTCAATCCTTGATTCTTTTTGATGAGCTAGGTCGTGGTACAGCAACCTATGACGGTATGG
CTTTGGCGCAATCAATCATTGAATATATCCATAATCATATCGGTGCAAAGACCATGTTTGCAACCCATTATCATGAGTTG
ACAGCTTTGTCAACAAGCTTGACGCACCTTATCAATGTTCACGTTGCGACTCTTGAGAAAAATGGTGATGTGACTTTTCT
TCATAAAATTGCAGAAGGTCCAGCAGACAAATCTTACGGAATTCATGTAGCAAAAATTGCTGGTTTACCAGAAGAATTAT
TACAACGTGCGGACAGCATTTTGACGAATTTAGAATCAGGTGCTGCGCAGCTTCAATTGACCCCTGAGGTAGAAGTTGGG
CCAATTACTGTAAAATCTGAAGTAGCAGAACCAGTGGCAGAGCAACTAAGTTTATTTGCTGATGACTCATCTAACCAAGA
AGTGATTGAAGCACTCAAAAAAGTTGATTTGATGAATTTAACACCAATGCAAGCCATGAATGTTATTTATGAATTAAAAA
ATATGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.43	100	0.724
mutS	Pseudomonas stutzeri strain ATCC 17587	37.716	100	0.382