Detailed information NTG0397079

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GH772_RS24415
• Genome accession: NZ_CP045777
• Coordinates: 4420082..4422682 (-)
• Length: 866 a.a.
• NCBI ID: WP_000365370.1
• Uniprot ID: A0A5M9GXY4
• Organism: Bacillus paranthracis strain CFSAN068816
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4415082..4427682

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GH772_RS24390 (GH772_24050)	fabH	4416328..4417260 (-)	933	WP_001100543.1	beta-ketoacyl-ACP synthase III	-
GH772_RS24395 (GH772_24055)	comZ	4417839..4418015 (-)	177	WP_009879752.1	ComZ family protein	Regulator
GH772_RS24400 (GH772_24060)	-	4418069..4418941 (-)	873	WP_000486161.1	NAD(P)-dependent oxidoreductase	-
GH772_RS24405 (GH772_24065)	-	4418971..4419705 (-)	735	WP_000028698.1	hydrolase	-
GH772_RS24410 (GH772_24070)	-	4419862..4420044 (+)	183	WP_001211114.1	YjzD family protein	-
GH772_RS24415 (GH772_24075)	clpC	4420082..4422682 (-)	2601	WP_000365370.1	ATP-dependent chaperone ClpB	Regulator
GH772_RS24420 (GH772_24080)	-	4422894..4423073 (-)	180	WP_000531421.1	YjzC family protein	-
GH772_RS24425 (GH772_24085)	-	4423568..4424377 (+)	810	WP_001041235.1	Cof-type HAD-IIB family hydrolase	-
GH772_RS24430 (GH772_24090)	-	4424483..4424623 (+)	141	WP_000516816.1	hypothetical protein	-
GH772_RS24435 (GH772_24095)	-	4424624..4424821 (+)	198	WP_000527391.1	DUF3813 domain-containing protein	-
GH772_RS24440 (GH772_24100)	-	4424847..4425704 (-)	858	WP_000364453.1	YitT family protein	-
GH772_RS24445 (GH772_24105)	-	4425805..4425936 (+)	132	WP_001120845.1	DUF3941 domain-containing protein	-
GH772_RS24450 (GH772_24110)	prsA	4426066..4426923 (+)	858	WP_001214227.1	peptidylprolyl isomerase PrsA	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97480.45 Da
• Isoelectric Point: 5.1561

>NTDB_id=397079 GH772_RS24415 WP_000365370.1 4420082..4422682(-) (clpC) [Bacillus paranthracis strain CFSAN068816]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGAEGLIKKKPSVTGSGAE
AGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFTEEKGDINQLFTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNRAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEDDGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=397079 GH772_RS24415 WP_000365370.1 4420082..4422682(-) (clpC) [Bacillus paranthracis strain CFSAN068816]
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCTCAATCTTTAGCGGTATCTCATCATCATCA
AGAAGTAGATACTGTTCATCTCTTGTTTACATTATTAGAAGAGCAAGATGGGCTAGCAGTACGTATTTTTCAAAAAATGA
ATGTCGATATAGAAGCGTTAAAACAAGGTGCTGAAGGTTTAATTAAGAAAAAGCCCTCTGTAACGGGAAGCGGTGCAGAA
GCAGGTAAATTATATATAACAGGTGCTTTGCAACAACTGCTTGTAAGAGCAGGAAAAGAAGCAGAAAAATTGCAAGATGA
TTACATTTCAGTTGAACATGTATTACTTGCTTTTACTGAAGAAAAAGGCGATATAAACCAATTATTTACAAGATTTCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTAAGAGCGGGGAAAATTGACCCTGTTATCGGCCGCGA
TAGTGAAATTCGCCGCGTAATCCGCATTCTTTCACGTAAAACGAAAAACAACCCAGTTTTAATTGGTGAACCAGGTGTTG
GTAAAACAGCAATTGTTGAAGGGTTAGCACAGCGTATTGTGAAAAAGGATGTACCTGAAGGATTAAAAGATAGAACAATT
TTTGCATTAGATATGAGTGCGCTTGTAGCTGGAGCGAAATTCCGCGGTGAGTTTGAGGAGCGTCTCCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGTCGTATTTTACTATTCATTGATGAACTTCACACAATCGTCGGCGCTGGTAAAACAGAAG
GCGCAATGGATGCAGGAAATATGTTAAAACCGATGCTTGCGCGTGGTGAACTGCATTGTATCGGGGCGACGACGTTAGAT
GAATATCGTAAATATATTGAGAAAGATCCAGCGCTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCCATTTTACGTGGTTTAAAAGAGCGCTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCAGTTTTATCAGATCGATATATTTCGGACCGTTTCTTACCAGATAAAGCAATTGATCTTGTCGATGAAGCG
TGTGCAACAATTCGTACAGAAATCGATTCTATGCCGACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTAGAAAT
TGAAGAAGCGGCTCTTGGAAAAGAAAAGGACTTTGGTAGCCAAGAACGTCTAAAAACGTTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTGGTATGAGAGCCAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAGAGCAGCGGAACTTCGCCACGG
AAAAATTCCTGCAATTGAAAAAGAGTTAAAAGAAGCAGAAGAAATGGGCGCGCATAATAAACAAGAAAATCGTTTATTAC
GTGAGGAAGTAAGTGAAGAAGAGATTGCTGATATTGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAAGGT
GAACGTGAGAAATTATTACGATTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGCTTAGTATC
AGACGCAGTTCTTCGTGCGCGCGCAGGTATCAAAGACCCGAACCGTCCGATTGGTTCCTTCATTTTCTTAGGACCTACTG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCATTATTCGATAGTGAAGAACAAATGATTCGTATTGATATG
TCTGAGTATATGGAGAAACACGCGGTGTCACGCTTAATTGGTGCGCCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCGTATTCGGTTATTTTATTAGACGAAATCGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGACGGTCGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACAGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGATGATGGCTCCATTAAAGAGGAATCAAGAGA
GCTTGTAATGGGACAATTAAGAGGACATTTCCGACCAGAGTTTTTAAACCGTGTCGACGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCACATTACG
GTAGAATTAACAGACGCAGCGAAAGAGTTTGTTGTCGAAGCTGGCTTCGATCCGATGTACGGAGCCCGTCCATTAAAAAG
ATATGTACAGCGTCAAGTTGAGACGAAATTAGCGAGAGAATTAATTGCAGGAACGATTACTGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTCGTTCATGTGAAGTAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• AAA lid domain (AAA_lid_9) (345-447)

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

3D structure

• AlphaFold DB: A0A5M9GXY4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. cremoris KW2	47.199	82.448	0.389