Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   STH8232_RS11985 Genome accession   NC_017581
Coordinates   1611281..1612084 (+) Length   267 a.a.
NCBI ID   WP_223899638.1    Uniprot ID   -
Organism   Streptococcus thermophilus JIM 8232     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1606281..1617084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STH8232_RS08310 (STH8232_1929) - 1606481..1606873 (-) 393 WP_003094909.1 hypothetical protein -
  STH8232_RS08315 (STH8232_1930) cipB 1606885..1607124 (-) 240 WP_011681565.1 Blp family class II bacteriocin Regulator
  STH8232_RS12265 (STH8232_1931) - 1607375..1607776 (-) 402 WP_011226490.1 hypothetical protein -
  STH8232_RS11435 (STH8232_1934) - 1608631..1608774 (-) 144 WP_014608661.1 hypothetical protein -
  STH8232_RS08330 (STH8232_1935) - 1608781..1609011 (-) 231 WP_014608662.1 bacteriocin class II family protein -
  STH8232_RS08335 (STH8232_1936) - 1609367..1609567 (-) 201 WP_011681569.1 hypothetical protein -
  STH8232_RS08340 (STH8232_1937) - 1609586..1609762 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  STH8232_RS08345 (STH8232_1938) - 1610013..1610750 (+) 738 WP_011681571.1 LytR/AlgR family response regulator transcription factor -
  STH8232_RS11985 comD/blpH 1611281..1612084 (+) 804 WP_223899638.1 ATP-binding protein Regulator
  STH8232_RS08355 (STH8232_1940) - 1612102..1612263 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  STH8232_RS08360 (STH8232_1941) comB 1612278..1613645 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator
  STH8232_RS08365 (STH8232_1942) - 1613661..1615815 (-) 2155 Protein_1573 peptide cleavage/export ABC transporter -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30641.92 Da        Isoelectric Point: 4.7379

>NTDB_id=39706 STH8232_RS11985 WP_223899638.1 1611281..1612084(+) (comD/blpH) [Streptococcus thermophilus JIM 8232]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEAYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=39706 STH8232_RS11985 WP_223899638.1 1611281..1612084(+) (comD/blpH) [Streptococcus thermophilus JIM 8232]
ATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAAAAAAATCTCCAGCTAG
AAAATCTCTACACCTACAATAAACATATTGAAGGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGCCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAACACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTCTACAAGCAGAAGAAGAAGGCATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCCTAA
AATTACTATTAGCTTTTGGGAAGATCATTGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAAAAAACAGAAA
CCAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363

Multiple sequence alignment