Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   FOC71_RS00650 Genome accession   NZ_CP053999
Coordinates   130398..132527 (-) Length   709 a.a.
NCBI ID   WP_003074018.1    Uniprot ID   -
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 125398..137527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS00620 (FOC71_00620) - 125481..126188 (-) 708 WP_003074030.1 L-ribulose-5-phosphate 4-epimerase -
  FOC71_RS00625 (FOC71_00625) - 126191..127054 (-) 864 WP_003074027.1 L-ribulose-5-phosphate 3-epimerase -
  FOC71_RS00630 (FOC71_00630) - 127060..127725 (-) 666 WP_003074026.1 3-keto-L-gulonate-6-phosphate decarboxylase UlaD -
  FOC71_RS00635 (FOC71_00635) - 127771..128256 (-) 486 WP_003074024.1 PTS sugar transporter subunit IIA -
  FOC71_RS00640 (FOC71_00640) - 128458..128739 (-) 282 WP_003074022.1 PTS sugar transporter subunit IIB -
  FOC71_RS00645 (FOC71_00645) - 128770..130230 (-) 1461 WP_003074020.1 PTS ascorbate transporter subunit IIC -
  FOC71_RS00650 (FOC71_00650) clpC 130398..132527 (-) 2130 WP_003074018.1 AAA family ATPase Regulator
  FOC71_RS00655 (FOC71_00655) - 132904..133209 (-) 306 WP_003074015.1 hypothetical protein -
  FOC71_RS00660 (FOC71_00660) - 133209..133619 (-) 411 WP_003074013.1 hypothetical protein -
  FOC71_RS00665 (FOC71_00665) - 133601..134863 (-) 1263 WP_003074011.1 alpha/beta fold hydrolase -
  FOC71_RS00670 (FOC71_00670) - 134875..135261 (-) 387 WP_003074009.1 DUF1310 family protein -
  FOC71_RS00675 (FOC71_00675) - 135304..135486 (-) 183 WP_003074007.1 hypothetical protein -
  FOC71_RS00680 (FOC71_00680) - 135489..135875 (-) 387 WP_003074006.1 DUF1310 family protein -
  FOC71_RS00685 (FOC71_00685) - 135930..136112 (-) 183 WP_003074003.1 hypothetical protein -
  FOC71_RS00690 (FOC71_00690) - 136114..136500 (-) 387 WP_003074001.1 DUF1310 family protein -
  FOC71_RS00695 (FOC71_00695) - 136715..137107 (-) 393 WP_003074000.1 DUF1310 family protein -

Sequence

Protein


Download         Length: 709 a.a.        Molecular weight: 78929.12 Da        Isoelectric Point: 4.8162

>NTDB_id=396966 FOC71_RS00650 WP_003074018.1 130398..132527(-) (clpC) [Streptococcus intermedius strain FDAARGOS_769]
MNNNYNNFDNMDDLFNQLMGRMGGFNSENRRYLINGREVTPEEFAQYRATGKLPKQVAEGQASQMQGQAGELKQDGILMK
LGRNLTEEARQDMLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEVVSIDIS
GLEAGTQYRGSFEENIQNLVSEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAEDTYKILQGIRDLYEKHHNVILPDDVLKAAVDFSIQYIPQRSLPDKAIDLVDVTAAHL
AAQHPVTDVHTVEREIAEQKKKQEAAVEKEDFETALNAKMRIEELEKKIENHTEDMKVTATVNDVAESVERMTGIPVSQM
GTSDIERLKEMNARLKTKVIGQNEAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKEAIIR
LDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFK
NTVIIATSNAGFGYESFTGDEEKDRKIMDRLKPYFRPEFLNRFNAVIEFSHLGKEDLAEIVDLMLDEVNQTLAKKDIMLT
VTDAAKHYLAEEGYDEVMGVRPLRRVIEQQIRDKVTDYHLDHLDAKHLLADLKDDELVIEEAKEHQTKK

Nucleotide


Download         Length: 2130 bp        

>NTDB_id=396966 FOC71_RS00650 WP_003074018.1 130398..132527(-) (clpC) [Streptococcus intermedius strain FDAARGOS_769]
ATGAACAATAACTATAACAACTTTGATAATATGGATGACCTTTTCAATCAATTGATGGGAAGAATGGGTGGTTTTAACAG
TGAAAATCGGCGTTATCTCATCAATGGACGTGAAGTGACACCAGAAGAATTTGCACAATATCGTGCAACAGGTAAATTAC
CGAAGCAAGTAGCGGAAGGTCAGGCATCACAAATGCAAGGACAAGCAGGTGAGCTTAAACAAGATGGTATTTTAATGAAG
TTAGGGCGTAATTTGACAGAAGAAGCACGTCAAGATATGTTAGATCCTGTTATTGGACGCAATAAGGAAATTCAAGAAAC
GGCTGAAATTCTTTCTCGGCGGACGAAAAACAATCCAGTATTAGTCGGAGACGCTGGAGTTGGTAAGACTGCAGTTGTCG
AAGGTTTAGCGCAAGCGATTGTTAATGGAGATGTTCCTGCAGCCATTAAGAATAAAGAGGTTGTTTCTATTGATATTTCT
GGTTTAGAAGCAGGGACACAGTATCGTGGTAGTTTTGAAGAAAATATTCAAAATTTAGTATCTGAAGTGAAAGAGGCTGG
CAATATCATTCTCTTCTTTGATGAAATTCATCAAATTCTGGGCGCTGGAAGCACAGGCGGTGATAGTGGATCAAAAGGTT
TAGCAGATATTTTGAAACCGGCTTTATCTCGTGGTGAACTGACAGTTATCGGTGCGACGACTCAGGATGAATATCGAAAT
ACCATTTTGAAGAATGCAGCTCTAGCTCGTCGCTTCAATGAAGTAAAAGTCAATGCCCCATCTGCAGAAGATACTTACAA
GATTTTGCAAGGAATTCGTGATTTATACGAAAAACACCACAATGTCATCTTGCCAGATGACGTGTTAAAAGCTGCCGTGG
ATTTCTCTATTCAATACATTCCGCAACGTAGCTTGCCGGATAAAGCGATTGACCTGGTGGATGTGACAGCGGCTCATTTA
GCAGCTCAACATCCTGTTACAGATGTGCATACAGTAGAACGTGAAATTGCAGAGCAAAAGAAAAAGCAAGAAGCTGCGGT
TGAAAAAGAAGACTTTGAAACTGCTTTGAATGCCAAGATGCGTATTGAAGAGCTAGAAAAAAAGATTGAAAATCATACGG
AAGACATGAAGGTGACTGCAACTGTCAATGATGTAGCAGAATCTGTAGAACGTATGACGGGTATTCCTGTTTCCCAAATG
GGGACTAGTGATATTGAACGGTTGAAAGAGATGAATGCGCGATTGAAGACAAAAGTCATTGGACAAAACGAAGCAGTTGA
AGCAGTGGCGCGCGCTATTCGTCGGAATCGTGCAGGTTTTGATGAAGGAAATCGTCCGATTGGTAGCTTTCTCTTTGTTG
GCCCAACTGGTGTTGGAAAAACAGAGCTAGCGAAGCAATTGGCGCTTGATATGTTTGGTACTAAAGAAGCTATTATCCGT
TTGGACATGTCTGAATACTCTGACCGCACAGCTGTGTCGAAATTGATTGGTACAACAGCTGGTTATGTGGGGTATGATGA
CAATAGTAACACGTTGACAGAACGTGTTCGTCGGAATCCTTACTCTATCATCTTGCTGGACGAAATTGAAAAAGCCGATC
CACAAGTCATCACATTGTTACTACAAGTTTTGGACGATGGACGTCTGACGGATGGACAAGGAAATACTGTCAACTTTAAG
AACACAGTTATTATTGCTACATCAAATGCTGGATTTGGGTATGAAAGCTTTACTGGTGATGAGGAAAAGGATAGGAAGAT
TATGGATCGCTTAAAACCATACTTCCGTCCAGAATTCTTGAATCGCTTCAATGCAGTCATTGAATTCTCTCATCTTGGTA
AAGAAGATTTAGCTGAAATCGTCGACTTGATGTTGGATGAGGTCAACCAAACACTTGCTAAGAAAGACATTATGCTAACA
GTAACAGATGCGGCCAAACATTATCTAGCAGAAGAGGGATATGATGAAGTTATGGGTGTTCGTCCGCTTCGTCGTGTGAT
TGAGCAACAAATCCGTGATAAGGTAACAGACTATCATCTTGATCATTTAGATGCGAAACATCTTCTTGCAGATTTGAAAG
ATGATGAATTAGTTATCGAAGAAGCGAAAGAGCATCAAACGAAAAAATAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(445-605)

ATPase family associated with various cellular activities (AAA) (AAA)

(120-252)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(612-682)

AAA lid domain (AAA_lid_9)

(261-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

51.506

88.999

0.458
  clpE Streptococcus mutans UA159

47.033

97.461

0.458
  clpE Streptococcus pneumoniae Rx1

45.69

98.166

0.449
  clpE Streptococcus pneumoniae D39

45.69

98.166

0.449
  clpE Streptococcus pneumoniae R6

45.69

98.166

0.449
  clpE Streptococcus pneumoniae TIGR4

45.455

97.743

0.444
  clpC Bacillus subtilis subsp. subtilis str. 168

47.368

91.114

0.432
  clpC Streptococcus pneumoniae Rx1

42.768

90.691

0.388
  clpC Streptococcus pneumoniae D39

42.768

90.691

0.388
  clpC Streptococcus pneumoniae TIGR4

42.613

90.691

0.386
  clpC Streptococcus mutans UA159

43.922

87.024

0.382
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.344

86.883

0.377
  clpC Streptococcus thermophilus LMD-9

42.626

87.024

0.371
  clpC Streptococcus thermophilus LMG 18311

42.464

87.024

0.37

Multiple sequence alignment