Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   GHB96_RS09825 Genome accession   NZ_CP045707
Coordinates   1898502..1901588 (-) Length   1028 a.a.
NCBI ID   WP_215772518.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain NG250     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1888369..1897850 1898502..1901588 flank 652


Gene organization within MGE regions


Location: 1888369..1901588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GHB96_RS09780 (GHB96_10320) dksA 1888716..1889132 (-) 417 WP_003692108.1 RNA polymerase-binding protein DksA -
  GHB96_RS09785 (GHB96_10325) proC 1889280..1890071 (-) 792 WP_003696395.1 pyrroline-5-carboxylate reductase -
  GHB96_RS09790 (GHB96_10330) - 1890120..1890527 (-) 408 WP_003690202.1 hypothetical protein -
  GHB96_RS09795 (GHB96_10335) - 1890527..1891213 (-) 687 WP_003690201.1 YggS family pyridoxal phosphate-dependent enzyme -
  GHB96_RS09800 (GHB96_10340) pilT 1891333..1892376 (+) 1044 WP_003690200.1 type IV pilus twitching motility protein PilT Machinery gene
  GHB96_RS09805 (GHB96_10345) - 1892540..1893766 (+) 1227 WP_003690199.1 PilT/PilU family type 4a pilus ATPase -
  GHB96_RS09810 (GHB96_10350) yccS 1893883..1896033 (+) 2151 WP_003690198.1 YccS family putative transporter -
  GHB96_RS09815 (GHB96_10355) - 1896913..1897197 (-) 285 WP_003701816.1 GIY-YIG nuclease family protein -
  GHB96_RS09820 (GHB96_10360) - 1897566..1897850 (-) 285 WP_003701816.1 GIY-YIG nuclease family protein -
  GHB96_RS09825 (GHB96_10365) pilC 1898502..1901588 (-) 3087 WP_215772518.1 PilC family type IV pilus tip adhesin Machinery gene

Sequence

Protein


Download         Length: 1028 a.a.        Molecular weight: 112725.92 Da        Isoelectric Point: 9.6452

>NTDB_id=396180 GHB96_RS09825 WP_215772518.1 1898502..1901588(-) (pilC) [Neisseria gonorrhoeae strain NG250]
MNKTLKRQVFRHTALYAAILMFSHTGGGGAMAQTYKYAIVMNAQNQPEVRRNGQYSTIKGKDREREYTYHNTRGGGGSVS
FNNTDTLVSQQSGTAVFGTATYLPPYGKVSGFDADALKERNNAVDWIRTTRIALAGYSYADVICKSGNQCPQLVYETKFA
FGQQGLQRKGNKLDIYEDKSRDNSPIYKLKDYPWLGVSFNLGSENTVKNSKSFNKLISSFNEDNNNQTIVSTTRDHPISL
GNWQREHTAVAYYLNAKLHLLDKKRIEDIAQGKTVDLGTLRPRVETTGRGWLSFWATWDIKDTGQIPVKLGLQVKAGRCI
NKPNPNNNTKAPSPALTAPALWFGPGQDGKVQMYSASVSTYPDSSSSKIFLQNLSRNDDKNKPGRYSLKPLSENEIKSKE
PRFNGRQTVIRLDSGVQLIKLNRSKDEVVIFGNTGNNGTFGIVKEANVNLEADEWKKVLLPWTVRGPDNDNKFKLINQKP
DKYSQRYRIRENGNRDLGDIVNSPITAVGGYLATAANDGMVHIFKKTGTDERGYELKLSYIPGTMPRQYFDNDTSALKDS
TLAQELRTFAEKGYVGDRYGVDGGFVLRQVELSGQKHVFMFGAMGLGGRGAYALDLSKINENYPAAAPLFDVKNGDNNGK
NRVEVELGYTVGTPQIGKIRNGKYAAFLASGYAAKDIDSQENKTALYVYDLKDTLGTPITKIDVPGGKGGLSSPTLVDKD
LDGIVDIAYAGDRGGNMYRFDLSNSDPSKWSVSTIFEGGKPITSAPAVSRLADKRVVIFGTGSDLSEEDVVGTNPQYIYG
IFDDDKGTVKVTVQNGTGGGLLEQVLSEENKILFLINNKASGGSADKGWVVKLREGERVTVKPTVVLRTAFVTIRKYTDT
DKCGAQTAILGINTADGGALTPRSARPIVPEANKDVAQYSGHKTAGGKSVPIGCMWKNSKTVCPNGYVYDKPVNVRYLDE
TETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3087 bp        

>NTDB_id=396180 GHB96_RS09825 WP_215772518.1 1898502..1901588(-) (pilC) [Neisseria gonorrhoeae strain NG250]
ATGAATAAAACTTTGAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACGTATAAATACGCTATTGTGATGAACGCGCAAAACCAGCCCGAGGTACGGCGGAATGGGC
AATATTCAACAATAAAGGGCAAAGACAGGGAGCGCGAATATACTTATCATAACACACGAGGAGGAGGAGGCTCTGTCTCA
TTCAACAATACCGATACCCTTGTTTCCCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGG
CAAGGTTTCCGGTTTTGATGCCGACGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCGTACCACCCGCATCGCGC
TGGCAGGCTACAGCTACGCCGACGTCATATGCAAAAGCGGCAACCAATGCCCCCAACTTGTCTATGAGACCAAATTTGCC
TTCGGTCAACAAGGGTTGCAAAGAAAGGGCAACAAGCTGGATATATACGAAGACAAAAGCCGCGACAATTCGCCCATTTA
CAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATAGCAAATCATTCA
ACAAATTGATATCTTCTTTTAATGAAGACAATAATAATCAAACCATCGTCTCTACGACACGAGACCACCCTATTTCCCTT
GGCAACTGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAAAAGGATTGA
AGATATCGCCCAAGGCAAAACAGTGGATTTGGGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAGGCTGGCTAAGTT
TTTGGGCTACGTGGGACATTAAAGATACCGGGCAGATTCCGGTCAAGCTCGGCCTGCAAGTCAAAGCAGGCCGCTGCATC
AACAAACCGAACCCCAATAATAATACCAAAGCCCCTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTTCGGACCCGGGCA
AGATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAGTTCGAGCAGCAAAATTTTCCTGCAAAACC
TTTCCCGCAATGATGACAAAAACAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTGAGAATGAGATTAAAAGTAAAGAG
CCGCGTTTCAACGGAAGGCAGACCGTCATCCGATTGGATAGCGGCGTACAGCTGATCAAACTGAATAGAAGCAAGGATGA
GGTCGTCATTTTTGGAAACACCGGCAACAACGGCACTTTCGGCATTGTTAAGGAAGCGAACGTCAATCTTGAAGCCGACG
AGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTCCCGATAATGACAATAAATTTAAATTAATTAACCAAAAACCA
GACAAATACAGCCAAAGATACCGCATCCGCGAAAACGGCAATCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGC
GGTCGGCGGGTATTTGGCAACCGCCGCGAACGACGGGATGGTGCATATCTTCAAAAAAACCGGCACGGATGAACGAGGCT
ACGAACTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCCGCTCTCAAAGACTCC
ACCCTCGCCCAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTT
GCGCCAAGTCGAACTGAGCGGGCAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTGGGCGGCAGAGGCGCGTATGCCT
TGGATTTAAGCAAAATCAACGAAAATTATCCGGCCGCCGCTCCCCTGTTTGATGTCAAAAATGGCGATAATAACGGCAAA
AATCGCGTGGAAGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAATCCGCAACGGCAAATACGCCGCCTT
CCTCGCCTCCGGTTATGCGGCTAAAGATATTGACAGCCAAGAAAATAAAACCGCGCTGTATGTATATGATTTGAAAGACA
CCTTAGGTACGCCGATTACAAAAATCGATGTGCCCGGCGGCAAAGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGAT
TTGGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGGAATATGTACCGCTTTGATTTGAGCAATTCCGATCC
TAGTAAATGGTCTGTAAGCACTATTTTCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACA
AACGCGTGGTCATCTTCGGCACGGGCAGCGATTTGAGTGAAGAGGATGTAGTCGGTACGAATCCACAATATATTTACGGT
ATCTTTGACGACGATAAGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGTTGCTCGAGCAAGTGCTTAG
CGAGGAAAATAAAATCTTGTTCCTGATAAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTGA
GGGAAGGAGAACGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTGACCATCCGGAAATATACGGATACG
GACAAATGTGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCC
GATTGTGCCGGAAGCCAATAAGGATGTCGCACAATATTCCGGCCATAAGACAGCCGGCGGCAAGTCCGTCCCCATAGGCT
GCATGTGGAAAAACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGTTATCTGGATGAA
ACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAGGCGTCCCGG
CAAAAACAACCGCTGCTTCTCCAAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCC
CGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(497-838)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

74.258

100

0.755

Multiple sequence alignment