Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   GE021_RS10735 Genome accession   NZ_CP053792
Coordinates   2194831..2197386 (-) Length   851 a.a.
NCBI ID   WP_125073895.1    Uniprot ID   A0A3P5XNG4
Organism   Streptococcus canis strain HL_77_1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2189831..2202386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS10720 (GE021_010710) - 2190052..2190429 (+) 378 WP_125073897.1 ArpU family phage packaging/lysis transcriptional regulator -
  GE021_RS10725 (GE021_010715) - 2190743..2193709 (+) 2967 WP_164407169.1 serum opacification factor -
  GE021_RS10730 (GE021_010720) - 2193817..2194434 (+) 618 WP_302051310.1 hypothetical protein -
  GE021_RS10735 (GE021_010725) hexA 2194831..2197386 (-) 2556 WP_125073895.1 DNA mismatch repair protein MutS Machinery gene
  GE021_RS10740 (GE021_010730) - 2197373..2197726 (-) 354 WP_125073894.1 YlbF family regulator -
  GE021_RS10745 (GE021_010735) argR 2197723..2198160 (-) 438 WP_125073893.1 arginine repressor -
  GE021_RS10750 (GE021_010740) argS 2198440..2200131 (+) 1692 WP_125073892.1 arginine--tRNA ligase -
  GE021_RS10755 (GE021_010745) abc-f 2200183..2201592 (-) 1410 WP_164407174.1 ribosomal protection-like ABC-F family protein -

Sequence

Protein


Download         Length: 851 a.a.        Molecular weight: 95137.71 Da        Isoelectric Point: 5.0572

>NTDB_id=394668 GE021_RS10735 WP_125073895.1 2194831..2197386(-) (hexA) [Streptococcus canis strain HL_77_1]
MAKANISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAIAEQMEDPKQAVGVVKREVVQVMTPGTVVDSTKPDSANNFLVAVDFDGYRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEVEQAILVKQMNLLLSYEDTIYEDSTLIDNQLTAVELSAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLDAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPAIKAILEAFNSAHINKLVKQLDTLPELEYLIRTAIDP
DAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLGLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESASLEYDIFMRIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYSRPSFN
DDHVIKIQDGRHAVVEKVMGVQEYIPNSISFDQKTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASANSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTMFATHYHEL
TELSNKLTQLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPEALLSRADDVLTRLEAQSQSAEIISVPSKA
EQASPVKDEQLSLFAADDKAQKVLQALETIDVLNITPLEAMTTLYELKKLL

Nucleotide


Download         Length: 2556 bp        

>NTDB_id=394668 GE021_RS10735 WP_125073895.1 2194831..2197386(-) (hexA) [Streptococcus canis strain HL_77_1]
ATGGCAAAAGCTAACATTTCTCCTGGAATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGGGACTTTTACGAGTTATTTTACGATGATGCTGTCAAGGCAGCGCAACTTTTAGAGATTGGTCTGACCAGTC
GCAATAAGAATGCGGAAAATCCAATTCCTATGGCAGGAGTGCCACATCACTCTGCCCAACAATACATTGATGTGTTAATT
GAATTGGGCTACAAGGTGGCTATTGCAGAACAAATGGAAGATCCCAAACAAGCTGTTGGGGTGGTTAAGCGTGAAGTTGT
TCAAGTGATGACACCAGGGACAGTTGTTGATTCAACCAAGCCAGATAGTGCCAACAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTACCGTTATGGATTGGCTTACATGGATGTGTCGACGGGTGAATTTTGCGTGACAGATTTGGCAGATTTTACAAGT
GTTCGTAGTGAAATTCAGAATCTCAAAGCAAAGGAAGTATTGTTAGGATTTGATTTGTCAGAGGTAGAGCAGGCTATTCT
GGTGAAGCAGATGAATCTGCTACTTTCCTATGAGGATACGATTTATGAAGATAGTACTCTGATTGACAATCAGTTGACAG
CAGTGGAGCTGTCAGCGGCAGGGAAACTCTTGCAATACGTTCATAAAACTCAAATGCGAGAACTTAGCCATTTGCAAGCA
TTGGTTCATTATGAAATCAAAGATTACTTACAAATGTCTTATGCTACCAAGTCAAGTTTGGATTTGGTTGAAAATGCCAG
AACAAATAAGAAACATGGCAGTCTCTATTGGCTTTTAGATGAAACCAAGACAGCTATGGGAATGCGTCTTTTACGGTCAT
GGATTGATAGACCTTTGGTTTCTAAAGAAGCTATCTTAGAACGCCAAGAGATTATTCAAGTTTTCTTAGACGCTTTTATT
GAGCGAACAGATTTAAGCAACAGTCTAAAAGGTGTTTACGATATTGAACGTTTGTCTAGTCGCGTTTCATTTGGCAAAGC
AAATCCTAAGGACTTGCTTCAATTGGGACACACATTGGCTCAAGTGCCAGCCATTAAAGCTATTTTAGAAGCTTTCAATA
GCGCTCATATTAATAAACTTGTCAAGCAACTTGACACACTGCCTGAGTTGGAATACCTGATACGAACAGCCATTGATCCT
GATGCACCAGCGACTATTAGTGAAGGCAGTATTATCCGAACTGGCTTTGATGAGCGCTTGGACCATTACCGTAAAGTGAT
GCGAGAAGGAACAGGCTGGATTGCTGATATTGAGGCCAAAGAACGTCAAGCAAGTGGCATTAATAATCTAAAAATTGATT
ATAATAAAAAAGATGGTTATTATTTCCACGTTACGAATTCAAATCTTGGCTTAGTGCCTGATCACTTTTTCAGAAAGGCT
ACTTTAAAAAATTCAGAACGTTATGGAACGGCAGAATTAGCTAAAATTGAAGGTCAGATGCTAGAGGCTAGGGAAGAATC
AGCTAGTTTAGAATACGATATTTTTATGCGTATTCGAGCTCAAGTGGAAACCTATATTAATCGCTTGCAGAAGCTTGCCA
AAACCTTGGCAACGGTTGATGTCTTGCAAAGTTTAGCAGTTGTTGCTGAGACGAACCATTACAGTCGGCCTAGTTTCAAT
GATGACCATGTGATTAAGATTCAAGATGGGCGTCATGCTGTCGTTGAAAAAGTTATGGGAGTGCAAGAGTACATTCCAAA
TAGTATTTCCTTTGATCAAAAAACAAGTATCCAATTGATTACGGGACCAAATATGAGTGGTAAGTCTACTTATATGCGAC
AGCTTGCCTTAACGGTTATCATGGCACAGATGGGCTCGTTTGTGGCTGCTGACCATGTTGATTTACCTTTATTTGATGCT
ATTTTCACACGTATTGGAGCTGCTGATGATTTGATTTCTGGACAGTCAACCTTTATGGTAGAGATGATGGAAGCAAACCA
AGCGATCAAACGTGCCAGTGCCAATTCGCTCATTTTATTTGATGAACTAGGACGAGGAACGGCAACCTATGATGGTATGG
CTCTAGCTCAGGCCATTATCGAATATATCCACGATAGGGTTGGTGCTAAAACCATGTTTGCAACGCATTATCATGAGTTG
ACAGAGTTGTCAAACAAGTTGACACAGCTAGTCAACGTTCATGTAGCAACGCTTGAAAAAGATGGAGATGTAACCTTCCT
TCACAAGATTGCGGAAGGGCCGGCAGACAAATCATACGGTATCCATGTGGCTAAAATAGCAGGACTTCCTGAAGCTCTAT
TAAGCAGAGCCGATGACGTTCTTACCCGCTTAGAAGCACAGTCACAGTCTGCTGAAATAATATCAGTCCCTTCAAAAGCT
GAGCAAGCAAGCCCTGTTAAAGACGAGCAATTATCACTTTTTGCTGCTGATGATAAAGCTCAGAAAGTTCTTCAAGCCCT
AGAAACCATTGATGTTCTGAATATCACTCCTTTAGAGGCCATGACGACCCTTTATGAGTTGAAAAAGTTATTATAG

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(599-785)

MutS domain I (MutS_I)

(8-118)

MutS domain II (MutS_II)

(126-239)

MutS domain III (MutS_III)

(256-546)

MutS family domain IV (MutS_IV)

(415-506)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P5XNG4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

71.395

100

0.716
  mutS Pseudomonas stutzeri strain ATCC 17587

37.31

100

0.375

Multiple sequence alignment