Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   GE022_RS10010 Genome accession   NZ_CP053790
Coordinates   2072167..2074722 (-) Length   851 a.a.
NCBI ID   WP_164405185.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2067167..2079722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS10000 (GE022_009990) - 2067831..2071052 (+) 3222 WP_172758338.1 serum opacification factor -
  GE022_RS10005 (GE022_009995) - 2071161..2071778 (+) 618 WP_338062211.1 hypothetical protein -
  GE022_RS10010 (GE022_010000) hexA 2072167..2074722 (-) 2556 WP_164405185.1 DNA mismatch repair protein MutS Machinery gene
  GE022_RS10015 (GE022_010005) - 2074709..2075062 (-) 354 WP_003045793.1 YlbF family regulator -
  GE022_RS10020 (GE022_010010) argR 2075059..2075496 (-) 438 WP_125073893.1 arginine repressor -
  GE022_RS10025 (GE022_010015) argS 2075776..2077467 (+) 1692 WP_164405184.1 arginine--tRNA ligase -
  GE022_RS10030 (GE022_010020) abc-f 2077519..2078928 (-) 1410 WP_164405183.1 ribosomal protection-like ABC-F family protein -

Sequence

Protein


Download         Length: 851 a.a.        Molecular weight: 95068.68 Da        Isoelectric Point: 5.1526

>NTDB_id=394563 GE022_RS10010 WP_164405185.1 2072167..2074722(-) (hexA) [Streptococcus canis strain HL_77_2]
MAKANISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSTKPDSANNFLVAVDFDGYRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEVEQAILVKQMNLLLSYEDTIYEDSTLIDNQLTAVELSAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLDAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPAIKAILEAFNSAHIDKLVKQLDTLPELEYLIRTAIDP
DAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLGLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESASLEYDIFMRIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYSRPSFN
DDHVIKIQDGRHAVVEKVMGVQEYIPNSISFDQKTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASANSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTMFATHYHEL
TELSKKLTQLVNVHVATLEKDGNVTFLHKIAEGPADKSYGIHVAKIAGLPEALLSRADDVLTRLEAQSQSAEIISVPSKA
EQASPVKDEHLSLFAADDKAQKVLQALEAIDVLNVTPLEAMTALYELKKLL

Nucleotide


Download         Length: 2556 bp        

>NTDB_id=394563 GE022_RS10010 WP_164405185.1 2072167..2074722(-) (hexA) [Streptococcus canis strain HL_77_2]
ATGGCAAAAGCTAACATTTCTCCTGGAATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTACGAGTTATTTTACGATGATGCTGTCAAGGCAGCGCAACTTTTAGAGATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCTATGGCAGGAGTGCCCCATCACTCTGCCCAGCAATACATTGATGTGTTAATT
GAATTGGGCTACAAGGTAGCTATCGCAGAACAAATGGAGGATCCCAAACAAGCTGTTGGGGTAGTTAAGCGTGAAGTTGT
TCAAGTGATTACACCAGGGACGGTTGTTGATTCAACTAAGCCAGATAGTGCCAACAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTACCGTTATGGATTGGCTTACATGGATGTGTCGACGGGTGAATTTTGCGTGACAGATTTGGCAGATTTCACAAGT
GTTCGTAGTGAAATTCAGAATCTCAAAGCAAAGGAAGTATTGTTAGGATTTGATTTGTCAGAGGTAGAGCAAGCTATTCT
GGTGAAGCAGATGAATCTGCTACTTTCCTATGAGGATACGATTTATGAAGATAGTACTCTGATTGACAATCAGTTGACAG
CAGTGGAGCTGTCAGCGGCAGGGAAACTCTTGCAATACGTTCATAAAACTCAAATGCGAGAACTTAGCCATTTGCAAGCA
TTGGTTCATTATGAAATCAAAGATTACTTACAAATGTCTTATGCTACCAAGTCAAGTTTGGATTTGGTTGAAAATGCCAG
AACAAATAAAAAACATGGCAGTCTCTACTGGCTTTTAGATGAGACCAAGACAGCTATGGGAATGCGTCTTTTACGGTCAT
GGATTGACAGACCTTTGGTTTCTAAAGAAGCTATCTTAGAACGCCAAGAGATTATTCAAGTTTTCTTAGACGCTTTTATT
GAGCGCACAGATTTAAGCAACAGTCTAAAAGGTGTTTACGATATTGAACGTTTGTCTAGTCGCGTTTCATTCGGCAAAGC
AAATCCTAAGGACTTGCTTCAATTGGGACACACATTGGCTCAAGTGCCAGCCATTAAAGCTATTTTAGAAGCTTTCAATA
GTGCTCATATTGATAAGCTTGTCAAGCAGCTTGACACACTGCCTGAGTTGGAGTACCTGATACGAACAGCTATTGATCCT
GACGCACCAGCGACTATTAGTGAAGGCAGTATTATCCGAACTGGCTTTGATGAACGCTTGGATCATTACCGTAAAGTGAT
GCGAGAAGGAACAGGCTGGATTGCAGATATTGAGGCTAAGGAACGTCAAGCAAGTGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTCCACGTTACGAATTCAAATCTTGGCTTAGTGCCTGATCACTTTTTCAGAAAGGCT
ACTTTAAAAAATTCAGAACGTTATGGAACGGCAGAATTAGCTAAAATAGAAGGTCAGATGCTAGAGGCTAGGGAAGAATC
AGCTAGTCTAGAATACGATATTTTTATGCGTATTCGAGCTCAAGTGGAAACCTATATTAATCGCTTGCAGAAGCTTGCCA
AAACCTTGGCAACGGTTGATGTCTTGCAAAGTTTAGCAGTTGTTGCTGAGACAAACCATTACAGTCGGCCTAGTTTCAAT
GATGACCATGTGATTAAGATTCAAGATGGACGTCATGCTGTTGTTGAAAAAGTTATGGGAGTGCAAGAATACATTCCAAA
TAGTATTTCCTTTGATCAAAAAACAAGTATCCAATTGATTACGGGACCAAATATGAGTGGTAAGTCTACTTATATGCGGC
AGCTTGCCTTAACGGTCATCATGGCACAGATGGGCTCGTTTGTGGCTGCTGACCATGTCGATTTGCCTTTATTTGATGCT
ATTTTCACACGTATTGGAGCTGCTGATGACTTGATTTCGGGACAGTCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCGATCAAACGTGCCAGTGCCAATTCGCTCATTTTATTTGATGAATTAGGACGAGGAACGGCAACCTATGATGGTATGG
CTCTAGCTCAGGCTATTATCGAATATATCCACGATAGGGTTGGTGCTAAAACCATGTTTGCAACGCACTATCATGAGTTG
ACAGAGTTGTCAAAAAAGTTGACACAGTTAGTCAACGTTCATGTAGCAACGCTTGAAAAAGATGGAAATGTAACCTTCCT
TCACAAGATTGCGGAAGGGCCGGCAGACAAATCATACGGTATTCATGTGGCTAAAATAGCAGGACTTCCTGAAGCTCTAT
TAAGCAGAGCCGATGACGTTCTTACCCGCTTAGAAGCACAGTCACAATCTGCTGAAATAATATCAGTCCCTTCAAAAGCT
GAGCAAGCAAGTCCTGTTAAAGACGAGCACTTATCACTTTTTGCTGCTGATGATAAAGCTCAGAAAGTTCTTCAAGCCTT
AGAAGCCATTGATGTTCTGAATGTCACTCCTTTAGAGGCCATGACTGCCCTTTATGAATTGAAAAAGTTATTATAA

Domains

Predicted by InterProScan.

MutS domain II (MutS_II)

(126-239)

MutS domain I (MutS_I)

(8-118)

MutS domain III (MutS_III)

(256-546)

MutS domain V (MutS_V)

(599-785)

MutS family domain IV (MutS_IV)

(415-506)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

71.395

100

0.716
  mutS Pseudomonas stutzeri strain ATCC 17587

37.544

100

0.377