Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   GE023_RS10295 Genome accession   NZ_CP053789
Coordinates   2096781..2099336 (-) Length   851 a.a.
NCBI ID   WP_093999157.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_98_2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2091781..2104336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS10285 (GE023_010280) - 2092549..2095680 (+) 3132 WP_254388698.1 serum opacification factor -
  GE023_RS10290 (GE023_010285) - 2095789..2096391 (+) 603 WP_232038594.1 hypothetical protein -
  GE023_RS10295 (GE023_010290) hexA 2096781..2099336 (-) 2556 WP_093999157.1 DNA mismatch repair protein MutS Machinery gene
  GE023_RS10300 (GE023_010295) - 2099323..2099676 (-) 354 WP_093999158.1 YlbF family regulator -
  GE023_RS10305 (GE023_010300) argR 2099673..2100110 (-) 438 WP_003045794.1 arginine repressor -
  GE023_RS10310 (GE023_010305) argS 2100390..2102081 (+) 1692 WP_093999159.1 arginine--tRNA ligase -
  GE023_RS10315 (GE023_010310) abc-f 2102133..2103542 (-) 1410 WP_159305733.1 ribosomal protection-like ABC-F family protein -

Sequence

Protein


Download         Length: 851 a.a.        Molecular weight: 95032.60 Da        Isoelectric Point: 5.0572

>NTDB_id=394462 GE023_RS10295 WP_093999157.1 2096781..2099336(-) (hexA) [Streptococcus canis strain HL_98_2]
MAKANISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSTKPDSANNFLVAVDFDGYRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEVEQAILVKQMNLLLSYEDTIYEDSTLIDNQLTAVELSAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPAIKAILEAFNSAHIDKLVKQLDTLPELEYLIRTAIDP
DAPATISEGSIIRTGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLGLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESASLEYDIFMRIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYSRPSFN
DDHVIKIQDGRHAVVEKVMGVQEYIPNSISFDQKTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASANSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTMFATHYHEL
TELSSKLTQLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPEALLSRADDVLTRLEAQSQSAEIISVPSKA
EQASPVKDEQLSLFAADDKAQKVIQALEAIDVLNITPLEAMTALYELKKLL

Nucleotide


Download         Length: 2556 bp        

>NTDB_id=394462 GE023_RS10295 WP_093999157.1 2096781..2099336(-) (hexA) [Streptococcus canis strain HL_98_2]
ATGGCAAAAGCTAACATTTCTCCTGGAATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTACGAGTTATTTTACGATGATGCTGTCAAGGCAGCGCAACTTTTAGAGATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCTATGGCAGGAGTGCCCCATCACTCTGCCCAGCAATACATTGATGTGTTAATT
GAATTGGGCTACAAGGTGGCTATTGCAGAACAAATGGAAGATCCCAAACAAGCTGTTGGGGTAGTTAAGCGTGAAGTTGT
TCAAGTGATTACACCAGGGACAGTTGTTGATTCAACCAAGCCAGATAGTGCCAACAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTACCGTTATGGATTGGCTTACATGGATGTGTCGACGGGTGAATTTTGCGTGACAGATTTGGCAGATTTCACAAGT
GTTCGTAGTGAAATTCAGAATCTCAAAGCAAAGGAAGTATTGTTAGGATTTGATTTGTCAGAGGTAGAGCAAGCTATTCT
GGTGAAGCAGATGAATCTGCTACTTTCCTATGAGGATACGATTTATGAAGATAGTACTCTGATTGACAATCAGTTGACAG
CAGTGGAGCTGTCAGCGGCAGGGAAACTCTTGCAATACGTTCATAAGACTCAAATGCGAGAACTTAGCCATTTGCAAGCA
TTGGTTCATTATGAAATCAAAGATTACTTACAAATGTCTTATGCTACCAAGTCAAGTTTGGATTTGGTTGAAAATGCCAG
AACAAATAAGAAACATGGCAGTCTCTACTGGCTTTTAGATGAGACCAAGACAGCTATGGGAATGCGTCTTTTACGGTCAT
GGATTGACAGACCTTTGGTTTCTAAAGAAGCTATCTTAGAACGCCAAGAGATTATTCAAGTTTTCTTAAACGCTTTTATT
GAGCGCACAGATTTAAGCAACAGTCTAAAAGGTGTTTACGATATTGAACGTTTGTCTAGTCGCGTTTCATTTGGCAAAGC
AAATCCTAAGGACTTGCTTCAATTGGGACACACATTGGCTCAAGTGCCAGCCATTAAAGCTATTTTAGAAGCTTTCAATA
GTGCTCATATTGATAAGCTTGTCAAGCAGCTTGACACACTGCCTGAGTTGGAATACCTGATACGAACAGCTATTGATCCT
GACGCACCAGCGACTATTAGTGAAGGCAGTATTATCCGAACTGGTTTTGATGAACGCTTGGATCATTACCGTAAAGTGAT
GCGAGAAGGAACAGGCTGGATTGCAGATATTGAGGCTAAGGAACGTCAAGCAAGTGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTCCACGTTACGAATTCAAATCTTGGCTTAGTGCCTGATCACTTTTTCAGAAAGGCT
ACTTTAAAAAATTCAGAACGTTATGGAACGGCAGAATTAGCTAAAATTGAAGGTCAGATGCTAGAGGCTAGAGAAGAATC
AGCTAGTCTAGAATACGATATTTTTATGCGTATTCGAGCTCAAGTGGAAACCTATATTAATCGCTTGCAGAAGCTTGCCA
AAACCTTGGCAACGGTTGATGTCTTGCAAAGTTTAGCAGTTGTTGCTGAGACGAACCATTACAGTCGGCCTAGTTTCAAT
GATGACCATGTGATTAAGATTCAAGATGGGCGTCATGCTGTTGTTGAAAAAGTTATGGGAGTGCAAGAATACATTCCAAA
TAGTATTTCCTTTGATCAAAAAACAAGTATCCAATTGATTACGGGACCAAATATGAGTGGTAAGTCTACTTATATGCGGC
AGCTTGCCTTAACGGTTATCATGGCACAGATGGGCTCGTTTGTGGCTGCTGACCATGTCGATTTGCCTTTGTTTGATGCT
ATTTTCACACGTATTGGAGCTGCTGATGATTTGATTTCTGGACAATCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCGATCAAACGTGCCAGTGCCAATTCGCTCATTTTATTTGATGAATTAGGACGAGGAACGGCAACCTATGATGGTATGG
CTCTAGCTCAGGCCATTATCGAATATATCCACGATAGGGTTGGTGCTAAAACCATGTTTGCAACGCACTATCATGAGTTG
ACAGAGTTGTCAAGCAAATTGACACAGTTAGTCAACGTTCATGTAGCAACGCTTGAAAAAGATGGAGATGTAACCTTCCT
TCACAAGATTGCGGAAGGGCCGGCAGACAAATCATACGGTATTCATGTGGCTAAAATAGCAGGACTTCCTGAAGCTCTAT
TAAGCAGAGCCGATGACGTTCTTACCCGCTTAGAAGCACAGTCACAATCTGCTGAAATAATATCAGTTCCTTCAAAAGCT
GAGCAAGCAAGTCCTGTTAAAGACGAGCAATTATCACTTTTTGCTGCTGATGATAAAGCTCAGAAAGTTATTCAAGCCTT
AGAAGCCATTGATGTTCTGAATATCACTCCTTTAGAGGCCATGACTGCCCTTTATGAATTGAAAAAGTTATTATAG

Domains

Predicted by InterProScan.

MutS domain II (MutS_II)

(126-239)

MutS domain III (MutS_III)

(256-546)

MutS family domain IV (MutS_IV)

(415-506)

MutS domain V (MutS_V)

(599-785)

MutS domain I (MutS_I)

(8-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

71.395

100

0.716
  mutS Pseudomonas stutzeri strain ATCC 17587

37.31

100

0.375