Detailed information NTG0394432

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: GAY69_RS11600
• Genome accession: NZ_CP045472
• Coordinates: 2402609..2403652 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ZY05
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2397609..2408652

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GAY69_RS11570 (GAY69_11775)	-	2398035..2398145 (+)	111	WP_001790257.1	hypothetical protein	-
GAY69_RS11575 (GAY69_11780)	-	2398174..2398587 (+)	414	WP_025174552.1	hypothetical protein	-
GAY69_RS11580 (GAY69_11790)	-	2399020..2400006 (-)	987	WP_000999708.1	aromatic acid exporter family protein	-
GAY69_RS11585 (GAY69_11795)	map	2400535..2401293 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
GAY69_RS11590 (GAY69_11800)	-	2401510..2401896 (+)	387	WP_001110179.1	hypothetical protein	-
GAY69_RS11595 (GAY69_11805)	liaF	2401911..2402612 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
GAY69_RS11600 (GAY69_11810)	vraS	2402609..2403652 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
GAY69_RS11605 (GAY69_11815)	vraR	2403642..2404271 (+)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
GAY69_RS11610 (GAY69_11820)	-	2404384..2405601 (-)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
GAY69_RS11615 (GAY69_11825)	-	2405879..2406154 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
GAY69_RS11620 (GAY69_11830)	-	2406161..2406625 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
GAY69_RS11625 (GAY69_11835)	-	2406772..2406972 (+)	201	WP_000180460.1	DUF1128 family protein	-
GAY69_RS11630 (GAY69_11840)	-	2406975..2408231 (+)	1257	WP_078065149.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=394432 GAY69_RS11600 WP_001017131.1 2402609..2403652(+) (vraS) [Staphylococcus aureus strain ZY05]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=394432 GAY69_RS11600 WP_001017131.1 2402609..2403652(+) (vraS) [Staphylococcus aureus strain ZY05]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1