Detailed information NTG0394125

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SA08028_RS14170
• Genome accession: NZ_CP045435
• Coordinates: 2792947..2793834 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain 08-028
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2787947..2798834

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA08028_RS14140	-	2787966..2788058 (+)	93	WP_010956583.1	hypothetical protein	-
SA08028_RS14145 (SA08028_02163)	-	2788166..2788663 (-)	498	WP_001065268.1	glutathione peroxidase	-
SA08028_RS14150	-	2788673..2788933 (-)	261	WP_001791974.1	hypothetical protein	-
SA08028_RS14155	-	2789315..2789428 (-)	114	Protein_2771	hypothetical protein	-
SA08028_RS14160 (SA08028_02164)	-	2790087..2792087 (-)	2001	WP_000776740.1	ABC transporter permease	-
SA08028_RS14165 (SA08028_02165)	-	2792084..2792839 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SA08028_RS14170 (SA08028_02166)	braS	2792947..2793834 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SA08028_RS14175 (SA08028_02167)	braR	2793845..2794510 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SA08028_RS14180 (SA08028_03405)	-	2794536..2794736 (-)	201	WP_000604727.1	hypothetical protein	-
SA08028_RS14185 (SA08028_02168)	-	2794934..2796358 (+)	1425	WP_000953748.1	alkaline phosphatase	-
SA08028_RS15090	-	2796418..2796519 (-)	102	WP_000731972.1	SE2200 family small protein	-
SA08028_RS14195 (SA08028_03407)	-	2796641..2797096 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SA08028_RS14200 (SA08028_02170)	-	2797341..2798102 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=394125 SA08028_RS14170 WP_000143417.1 2792947..2793834(-) (braS) [Staphylococcus aureus strain 08-028]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=394125 SA08028_RS14170 WP_000143417.1 2792947..2793834(-) (braS) [Staphylococcus aureus strain 08-028]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99