Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GCU76_RS06295 Genome accession   NZ_CP045425
Coordinates   1207459..1208115 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis strain JAAA     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1202459..1213115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GCU76_RS06265 oppF 1202711..1203628 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  GCU76_RS06270 yjbB 1203735..1204952 (+) 1218 WP_152425670.1 MFS transporter -
  GCU76_RS06275 yjbC 1205117..1205695 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  GCU76_RS06280 spx 1205876..1206271 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  GCU76_RS06285 yjbE 1206526..1207182 (-) 657 WP_003232944.1 TerC family protein -
  GCU76_RS06290 - 1207352..1207492 (+) 141 WP_119122854.1 hypothetical protein -
  GCU76_RS06295 mecA 1207459..1208115 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  GCU76_RS06300 - 1208110..1208232 (-) 123 WP_003245684.1 hypothetical protein -
  GCU76_RS06305 coiA 1208276..1209427 (+) 1152 WP_017695683.1 competence protein CoiA Machinery gene
  GCU76_RS06310 pepF 1209657..1211486 (+) 1830 WP_171518460.1 oligoendopeptidase F -
  GCU76_RS06315 - 1211524..1211691 (-) 168 WP_003244944.1 hypothetical protein -
  GCU76_RS06325 spxH 1212005..1212904 (-) 900 WP_041340381.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=393974 GCU76_RS06295 WP_003232942.1 1207459..1208115(+) (mecA) [Bacillus subtilis strain JAAA]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=393974 GCU76_RS06295 WP_003232942.1 1207459..1208115(+) (mecA) [Bacillus subtilis strain JAAA]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTTGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment