Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   GYMC52_RS12390 Genome accession   NC_014915
Coordinates   2526854..2527927 (-) Length   357 a.a.
NCBI ID   WP_012820549.1    Uniprot ID   A0A0E0TDW8
Organism   Geobacillus sp. Y412MC52     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 2528132..2529319 2526854..2527927 flank 205


Gene organization within MGE regions


Location: 2526854..2529319
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GYMC52_RS12390 (GYMC52_2464) comGA 2526854..2527927 (-) 1074 WP_012820549.1 competence type IV pilus ATPase ComGA Machinery gene
  GYMC52_RS12395 (GYMC52_2465) - 2528132..2529319 (+) 1188 WP_012820547.1 IS701 family transposase -

Sequence

Protein


Download         Length: 357 a.a.        Molecular weight: 39650.13 Da        Isoelectric Point: 8.1836

>NTDB_id=39377 GYMC52_RS12390 WP_012820549.1 2526854..2527927(-) (comGA) [Geobacillus sp. Y412MC52]
MLNEIEQTANRLLAEAVQRRASDLHLVPRRRDAAVRLRLDGMLVDVGALPKETAERLIVHFKFLAGMDIGERRRPQSGAM
EVAEFGETVYLRLSTLPTLYDESLVIRLLPQRLPLPLRELSLFFHSTARLFSFMQHPQGLVLLTGPTGSGKTTTLYTLLD
LCQAERQRNIITLEDPIEKQNERLLQVQINEKAGITYAAGLKAALRHDPDVLMVGEIRDHDTAAIAIRSALSGHLVVSTM
HAADAVGAVYRLHEFGIPLGDLAETLLAVSAQRLVELCCPLCGDDCHPSCGRLGRRRRTAVYELLCGSALEDVIHFLSNG
RGKPKRSYMTLARLIRKGIALGYLPVRMLELVGGEER

Nucleotide


Download         Length: 1074 bp        

>NTDB_id=39377 GYMC52_RS12390 WP_012820549.1 2526854..2527927(-) (comGA) [Geobacillus sp. Y412MC52]
GTGCTGAACGAGATCGAACAAACGGCAAACCGCCTTCTCGCCGAAGCGGTGCAGCGCCGCGCCTCGGATCTCCACCTCGT
TCCGCGCCGCCGTGATGCCGCCGTTCGTCTTCGGCTCGATGGCATGCTTGTCGACGTTGGCGCTCTTCCGAAAGAAACGG
CGGAACGTCTCATCGTCCACTTTAAATTTTTAGCCGGCATGGACATCGGGGAACGACGCCGTCCGCAAAGCGGCGCCATG
GAAGTGGCGGAGTTTGGGGAAACGGTGTATTTGCGTTTATCGACATTGCCAACGCTCTACGACGAAAGTCTTGTCATTCG
ACTTCTGCCGCAGCGACTCCCGCTGCCGCTTCGCGAACTATCCTTATTCTTCCACTCCACCGCACGATTATTTTCCTTCA
TGCAGCATCCGCAAGGACTCGTGCTGTTGACCGGTCCGACGGGGTCGGGAAAAACGACGACCCTGTACACCCTTCTTGAT
CTTTGCCAAGCGGAAAGGCAACGCAACATCATCACGCTTGAAGATCCAATCGAAAAACAGAACGAACGACTGTTGCAAGT
GCAAATCAATGAAAAAGCAGGCATCACATACGCCGCTGGGTTAAAAGCGGCGCTGCGCCATGACCCGGATGTGTTGATGG
TCGGCGAGATCCGCGATCATGACACGGCGGCCATTGCCATCCGTTCAGCGTTGAGCGGCCATTTGGTCGTCTCGACGATG
CACGCCGCCGATGCAGTCGGCGCCGTCTACCGGCTGCATGAATTCGGCATTCCGCTCGGCGATTTGGCTGAGACGCTGCT
TGCCGTCTCTGCCCAGCGGCTTGTCGAGCTTTGCTGCCCGTTGTGCGGCGACGATTGCCATCCATCGTGCGGCCGTCTTG
GGCGCCGCCGGCGCACGGCTGTTTATGAGTTGCTTTGCGGTTCAGCCCTGGAGGACGTGATTCATTTTCTCTCCAATGGG
AGAGGGAAGCCCAAGCGCTCTTATATGACGCTCGCTCGCTTGATCCGCAAGGGGATTGCGCTTGGCTACCTGCCCGTCCG
CATGCTTGAGCTCGTCGGAGGGGAAGAAAGATGA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(12-276)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E0TDW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Bacillus subtilis subsp. subtilis str. 168

50.581

96.359

0.487

Multiple sequence alignment