Detailed information NTG0393325

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: GCB94_RS14355
• Genome accession: NZ_CP045306
• Coordinates: 3019414..3021636 (+)
• Length: 740 a.a.
• NCBI ID: WP_003635596.1
• Uniprot ID: D3HKP4
• Organism: Legionella longbeachae strain B1445CHC
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3014414..3026636

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GCB94_RS14330 (GCB94_14265)	-	3014655..3015293 (-)	639	WP_003635606.1	hypothetical protein	-
GCB94_RS14335 (GCB94_14270)	-	3015535..3016560 (-)	1026	WP_003635604.1	spermidine/putrescine ABC transporter substrate-binding protein	-
GCB94_RS14340 (GCB94_14275)	-	3016557..3017324 (-)	768	WP_003635601.1	ABC transporter permease subunit	-
GCB94_RS14345 (GCB94_14280)	-	3017321..3018145 (-)	825	WP_003635599.1	ABC transporter permease subunit	-
GCB94_RS14350 (GCB94_14285)	potA	3018135..3019229 (-)	1095	WP_003635598.1	spermidine/putrescine ABC transporter ATP-binding protein PotA	-
GCB94_RS14355 (GCB94_14290)	comEC	3019414..3021636 (+)	2223	WP_003635596.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GCB94_RS14360 (GCB94_14295)	-	3021746..3022795 (+)	1050	WP_003635594.1	trifunctional transcriptional activator/DNA repair protein Ada/methylated-DNA--[protein]-cysteine S-methyltransferase	-
GCB94_RS14365 (GCB94_14300)	-	3023152..3023379 (-)	228	WP_172622913.1	hypothetical protein	-
GCB94_RS14370 (GCB94_14305)	-	3023805..3024620 (-)	816	WP_003635585.1	mechanosensitive ion channel family protein	-
GCB94_RS14375 (GCB94_14310)	-	3024943..3025251 (-)	309	WP_243753467.1	hypothetical protein	-
GCB94_RS14380 (GCB94_14315)	-	3025601..3025987 (+)	387	WP_003635579.1	group III truncated hemoglobin	-
GCB94_RS14385	cydP	3025981..3026151 (+)	171	WP_003635577.1	cytochrome oxidase putative small subunit CydP	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 83609.84 Da
• Isoelectric Point: 9.6797

>NTDB_id=393325 GCB94_RS14355 WP_003635596.1 3019414..3021636(+) (comEC) [Legionella longbeachae strain B1445CHC]
MEIFCFFIGILYRYTLHGLLPILILFIFFIIPRYANILFFLLGIFIATVHQSQNLPKGLPDVEVIPQVSIQGTIASIPLQ
SPSKTLFLLALEQYDNHPAQGIIQLSWYNKAPKIHVGQRWKFKVKLKKPRNYLNPGSMDYVRSLATRHILWTGYIHSRGN
KQLPKVPSSFNWLELREQLSEQLGLLAPDQKTAGIVEALALNITTHIDQKSWDLFRRTGTTHLFGISGEHIALISGIIYW
LLRWIWTRSSRLCLRIPAPHIASMGGLLAASGYAFLAGFAPPVQRALIGCFFYTLYSLGYQRFTPWQVWRYALCGVLLIE
PHAVFMQGFYFSFLAVACLLLTQQRWRLKGYKASLALQLSCLIGLMPLTLYWYAYGSINGFIANLFAIPLVGLLIVPLSL
MTMTVSSLSIAKILMKAVSLLITLLFKGLSLSEYLAALNINCPIYSIELALVLIGALLMWVLLPTKPFQWIAMLWLLLPF
FPPRTIIQAGEAKIDVLDVGQGLAVAIRTQHHVLLYDTGDRFFQGNDLGKMVILPYLNTLGIKKIDTIVVSHPDKDHLGG
LKSLEKEIPVERLLVNEPHFYHRGLKCHDYPPWQWDGVSFRFLPIKIPLRGKNNSSCILQIETHAGRMLLAGDIEKIAED
YLVQTYGNILESDVLLVPHHGSKTSSSYRFLLEVAPLYAIASLGFDNRFHFPHDKTLANMKKLNIPFYRTDTCGMVQITL
PAQGALTHPTCFSGQRLQPV

Nucleotide

• Length: 2223 bp

>NTDB_id=393325 GCB94_RS14355 WP_003635596.1 3019414..3021636(+) (comEC) [Legionella longbeachae strain B1445CHC]
ATGGAAATTTTTTGCTTTTTTATAGGCATATTGTATCGATATACCTTACACGGATTATTGCCTATACTTATTTTATTTAT
TTTTTTCATTATTCCCAGGTATGCGAATATCCTGTTTTTTCTTTTAGGCATCTTCATCGCGACTGTGCACCAATCTCAAA
ATTTACCAAAAGGATTACCCGATGTTGAAGTAATACCCCAAGTCAGCATCCAAGGAACAATTGCATCTATTCCGCTCCAA
AGTCCATCTAAGACACTCTTTTTATTGGCTTTAGAACAATACGACAATCATCCAGCACAAGGGATAATACAATTATCATG
GTATAACAAAGCCCCCAAAATCCATGTAGGGCAACGATGGAAATTTAAAGTGAAATTGAAAAAGCCAAGAAATTATCTAA
ATCCAGGGAGTATGGATTATGTACGTTCACTCGCAACACGCCATATATTGTGGACTGGATATATTCATTCTAGAGGAAAT
AAGCAACTCCCAAAAGTCCCCTCATCTTTCAATTGGCTAGAACTAAGGGAACAATTAAGCGAGCAACTCGGCTTGTTGGC
ACCTGATCAAAAAACCGCTGGAATTGTAGAGGCTTTAGCTTTAAATATAACAACCCATATTGACCAGAAAAGCTGGGATT
TGTTTAGACGTACTGGCACAACCCATTTATTTGGTATTTCAGGTGAACATATCGCCTTAATTTCAGGTATTATTTATTGG
TTACTCCGTTGGATATGGACTCGAAGCTCTCGTCTTTGCTTACGCATTCCAGCCCCTCATATTGCAAGTATGGGTGGCCT
TTTGGCTGCATCAGGATATGCGTTTTTAGCAGGTTTTGCACCTCCTGTCCAAAGGGCACTTATCGGATGTTTTTTTTATA
CCCTTTATAGCTTGGGCTACCAGCGTTTTACTCCATGGCAAGTATGGCGCTATGCTCTATGTGGTGTCTTATTGATTGAA
CCACATGCCGTATTTATGCAAGGATTCTATTTTTCTTTTCTTGCAGTAGCATGCTTGCTCTTAACACAACAACGCTGGCG
TTTAAAAGGATATAAAGCCTCTTTAGCCCTACAGTTAAGCTGTTTAATTGGGTTAATGCCCCTAACCTTATATTGGTATG
CTTATGGCTCAATTAATGGATTTATTGCAAACCTTTTCGCTATACCTTTGGTGGGATTACTCATTGTTCCGTTGTCATTA
ATGACAATGACGGTCAGCTCTTTAAGCATTGCAAAGATACTAATGAAGGCCGTTTCTTTACTCATTACCCTATTGTTTAA
AGGGCTATCCTTGTCAGAATATTTAGCTGCTCTAAATATTAATTGCCCCATTTATTCTATAGAACTGGCTCTTGTTCTAA
TTGGAGCTTTATTGATGTGGGTTTTACTACCCACTAAACCTTTTCAATGGATCGCGATGCTTTGGTTATTGCTCCCGTTT
TTTCCACCGCGAACAATCATTCAAGCAGGCGAAGCCAAAATAGATGTTTTGGACGTAGGGCAAGGCTTGGCTGTTGCGAT
TCGAACGCAACACCATGTATTGCTTTATGATACAGGAGATCGTTTCTTTCAAGGAAATGATTTAGGGAAAATGGTTATTT
TGCCTTATCTTAACACTTTGGGTATCAAAAAAATTGATACCATAGTTGTGAGCCATCCTGATAAAGATCATCTTGGAGGA
CTTAAATCACTGGAAAAAGAAATACCAGTAGAGAGGCTATTAGTCAATGAGCCTCATTTCTATCATCGTGGTTTAAAATG
TCATGATTATCCACCATGGCAATGGGACGGTGTTTCGTTCCGTTTTCTGCCAATAAAAATTCCCCTTAGAGGAAAAAACA
ACAGTTCTTGCATTTTACAAATAGAAACACATGCAGGACGGATGCTCTTAGCTGGCGATATTGAAAAAATAGCTGAAGAT
TATCTGGTGCAGACTTATGGCAATATTCTTGAATCAGATGTGCTGCTTGTTCCTCATCATGGCAGTAAAACTTCATCATC
CTACAGATTCTTATTAGAAGTTGCTCCGCTCTATGCTATAGCCTCCCTGGGCTTTGATAATCGCTTTCACTTTCCCCATG
ACAAGACTTTAGCAAACATGAAAAAACTGAATATCCCTTTTTACAGAACAGATACTTGTGGCATGGTACAGATTACTTTG
CCTGCCCAAGGAGCACTCACTCATCCCACTTGCTTTAGTGGACAGAGGTTACAACCCGTGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (201-465)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-676)

• Domain of unknown function (DUF4131) (DUF4131) (16-157)

3D structure

• AlphaFold DB: D3HKP4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Legionella pneumophila strain Lp02	64.305	99.189	0.638
comEC	Legionella pneumophila strain ERS1305867	63.81	99.324	0.634