Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   LV515_RS04495 Genome accession   NZ_CP045240
Coordinates   936602..937432 (+) Length   276 a.a.
NCBI ID   WP_003717124.1    Uniprot ID   C2ESP1
Organism   Limosilactobacillus vaginalis strain LV515     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 931602..942432
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV515_RS04485 (LV515_04485) - 932210..934519 (-) 2310 WP_040531209.1 hypothetical protein -
  LV515_RS04490 (LV515_04490) - 934645..936420 (-) 1776 WP_040531211.1 oleate hydratase -
  LV515_RS04495 (LV515_04495) endA 936602..937432 (+) 831 WP_003717124.1 DNA/RNA non-specific endonuclease Machinery gene
  LV515_RS04500 (LV515_04500) - 937492..938871 (-) 1380 WP_040531214.1 amino acid permease -
  LV515_RS04505 (LV515_04505) - 939159..940673 (-) 1515 WP_040531218.1 hypothetical protein -

Sequence

Protein


Download         Length: 276 a.a.        Molecular weight: 30636.40 Da        Isoelectric Point: 10.5992

>NTDB_id=392876 LV515_RS04495 WP_003717124.1 936602..937432(+) (endA) [Limosilactobacillus vaginalis strain LV515]
MKFRKRLYHLLFALVGLLIVTGVIQQPKLTSASLNHISKIAYWKKTSHSYQKTLPPTQEQASSVLTPAVRQQLGTAITWN
KAGAFIINNNQTNLNAKIASAPYAVNHLDRQGRAWQGDAWLNRTTRQYKNRTATGNGATNWRPAGFLQAHNLKGGYNHAY
DRGHLLGYALVGGIHGFDASESNPSNIATQTAWANEARNKNSTGQNYYEGLVRKALDQNKQVRYRVTNIYDGNNIVPAGV
HIEAKSSDGSLEYNVFVPNVQRNITINYSTGAVKQN

Nucleotide


Download         Length: 831 bp        

>NTDB_id=392876 LV515_RS04495 WP_003717124.1 936602..937432(+) (endA) [Limosilactobacillus vaginalis strain LV515]
ATGAAATTTAGAAAACGACTCTATCACCTTTTATTTGCTCTTGTTGGTTTATTAATAGTTACTGGAGTTATCCAGCAGCC
TAAGCTAACGAGTGCTTCATTAAACCATATTAGTAAAATTGCATACTGGAAGAAAACTAGTCACAGCTATCAAAAAACAT
TGCCACCAACTCAGGAACAGGCTAGTTCAGTTTTGACTCCGGCTGTTCGCCAACAACTTGGTACTGCAATTACTTGGAAT
AAAGCTGGTGCATTTATTATTAATAATAACCAAACTAATCTTAACGCTAAGATTGCAAGTGCTCCCTATGCTGTAAATCA
TCTTGACCGCCAAGGAAGAGCCTGGCAAGGTGATGCCTGGTTAAACAGAACAACTCGTCAATATAAAAATCGAACTGCTA
CTGGGAATGGTGCTACGAATTGGCGACCAGCTGGTTTTCTTCAGGCTCATAATCTTAAGGGTGGGTACAATCACGCATAC
GATCGGGGACACCTTCTTGGTTATGCGCTAGTTGGCGGTATTCATGGATTTGATGCATCCGAATCAAATCCATCTAATAT
TGCCACGCAAACTGCCTGGGCAAATGAAGCACGAAATAAAAATTCAACAGGACAAAACTACTATGAAGGTCTGGTCCGAA
AAGCACTAGATCAAAATAAACAAGTTCGCTACCGGGTCACAAATATTTATGACGGTAATAATATTGTTCCGGCTGGTGTT
CACATCGAAGCTAAGTCTAGCGATGGCTCTTTAGAATATAATGTTTTCGTGCCAAATGTCCAAAGAAATATTACGATTAA
CTATTCAACTGGCGCAGTAAAGCAAAATTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(84-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C2ESP1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

58.009

83.696

0.486
  endA Streptococcus pneumoniae D39

58.009

83.696

0.486
  endA Streptococcus pneumoniae R6

58.009

83.696

0.486
  endA Streptococcus pneumoniae TIGR4

58.009

83.696

0.486

Multiple sequence alignment