Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   GAN21_RS08175 Genome accession   NZ_CP045086
Coordinates   1739243..1739959 (-) Length   238 a.a.
NCBI ID   WP_100006618.1    Uniprot ID   -
Organism   Staphylococcus pseudintermedius strain KCTC 43136     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1734243..1744959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GAN21_RS08160 - 1735748..1736695 (+) 948 WP_063278589.1 LacI family DNA-binding transcriptional regulator -
  GAN21_RS08165 - 1736751..1738235 (+) 1485 WP_063278588.1 sucrose-6-phosphate hydrolase -
  GAN21_RS08170 - 1738239..1739183 (+) 945 WP_115807334.1 carbohydrate kinase family protein -
  GAN21_RS08175 agrA 1739243..1739959 (-) 717 WP_100006618.1 quorum-sensing response regulator AgrA Regulator
  GAN21_RS08180 agrC 1739973..1741265 (-) 1293 WP_152162931.1 quorum-sensing sensor histidine kinase AgrC -
  GAN21_RS08185 agrD 1741289..1741426 (-) 138 WP_063278585.1 cyclic lactone autoinducer peptide AgrD -
  GAN21_RS08190 - 1741428..1741994 (-) 567 WP_140232597.1 accessory gene regulator AgrB -
  GAN21_RS12990 - 1742386..1742466 (+) 81 WP_110144734.1 delta-lysin family phenol-soluble modulin -
  GAN21_RS08200 - 1742751..1743554 (-) 804 WP_099987197.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28016.18 Da        Isoelectric Point: 5.4368

>NTDB_id=391784 GAN21_RS08175 WP_100006618.1 1739243..1739959(-) (agrA) [Staphylococcus pseudintermedius strain KCTC 43136]
MKILICEDDPKQRERMVSIIENYIMIEEKPMKIELATNDPYAILETSKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPEELRTRIIDCLETALKRLDLLTKDHTVETLELKRGTSSVYVNYDEVM
FFESSPKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSYVLNRRNITSVDTKERIAYFKNEEFCYVSVRNLKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=391784 GAN21_RS08175 WP_100006618.1 1739243..1739959(-) (agrA) [Staphylococcus pseudintermedius strain KCTC 43136]
ATGAAAATTTTGATTTGTGAGGATGATCCTAAACAACGCGAACGTATGGTGTCCATTATTGAAAACTATATTATGATTGA
AGAGAAGCCGATGAAAATTGAGCTTGCTACCAATGACCCTTATGCTATCTTAGAAACTTCTAAAAACATGACTGATATTG
GCTGCTACTTTTTAGATATTCAATTAGAGTCTGATATTAACGGGATTAAATTAGGGAGCGAAATTCGTAAGCACGATCCT
GTTGGGAATATTATTTTTGTGACGAGTCATAGTGAGCTGACGTACTTGACGTTTGTCTATAAAGTGGCTGCCATGGATTT
TATTTTTAAAGATGATCCTGAAGAATTAAGGACACGCATTATCGATTGTTTAGAAACAGCATTAAAACGGCTTGATTTAT
TAACAAAAGATCATACTGTTGAAACTTTGGAACTCAAACGTGGAACAAGCTCGGTTTACGTGAACTATGACGAAGTGATG
TTTTTCGAGTCTTCACCGAAGTCACATCGTTTAATCGCGCATTTAGACAATCGTCAAATCGAATTTTACGGCAATTTGAA
AGAGTTAGCTCAACTCGATGATCGATTCTTCAGATGCCACAACAGTTATGTGCTAAACAGAAGAAATATTACAAGTGTCG
ATACGAAAGAACGGATTGCTTATTTCAAAAATGAAGAATTTTGTTACGTGTCGGTGCGTAATTTGAAGAAAATTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(152-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

82.773

100

0.828

Multiple sequence alignment