Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   HA034_RS08280 Genome accession   NZ_CP053356
Coordinates   1583266..1583940 (-) Length   224 a.a.
NCBI ID   WP_001166500.1    Uniprot ID   Q99VW2
Organism   Staphylococcus aureus strain 14507     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1578266..1588940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HA034_RS14655 - 1579306..1579377 (+) 72 Protein_1585 hypothetical protein -
  HA034_RS08265 (HA034_08270) vraG 1579449..1581338 (-) 1890 WP_000143607.1 ABC transporter permease VraG -
  HA034_RS08270 (HA034_08275) vraF 1581328..1582089 (-) 762 WP_000985996.1 ABC transporter ATP-binding protein VraF -
  HA034_RS08275 (HA034_08280) graS 1582233..1583273 (-) 1041 WP_001061264.1 histidine kinase GraS/ApsS -
  HA034_RS08280 (HA034_08285) braR 1583266..1583940 (-) 675 WP_001166500.1 response regulator transcription factor GraR/ApsR Regulator
  HA034_RS08285 (HA034_08290) graX 1583956..1584879 (-) 924 WP_000802953.1 auxiliary protein GraX/ApsX -
  HA034_RS08290 (HA034_08295) - 1584992..1585498 (+) 507 WP_000940129.1 GNAT family N-acetyltransferase -
  HA034_RS08295 (HA034_08300) - 1585707..1586135 (-) 429 WP_000198504.1 hypothetical protein -
  HA034_RS08300 (HA034_08305) - 1586464..1587507 (-) 1044 WP_001030772.1 alpha/beta hydrolase -
  HA034_RS08305 (HA034_08310) - 1587658..1588725 (-) 1068 WP_000980137.1 membrane protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26065.87 Da        Isoelectric Point: 4.3563

>NTDB_id=391744 HA034_RS08280 WP_001166500.1 1583266..1583940(-) (braR) [Staphylococcus aureus strain 14507]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=391744 HA034_RS08280 WP_001166500.1 1583266..1583940(-) (braR) [Staphylococcus aureus strain 14507]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAACCTTTCTATACCAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGACGATACGATTTTTCTATCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATTAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(149-221)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q99VW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.455

98.214

0.397

Multiple sequence alignment