Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   OCEPR_RS03820 Genome accession   NC_014761
Coordinates   764895..765812 (-) Length   305 a.a.
NCBI ID   WP_013457385.1    Uniprot ID   E4U786
Organism   Oceanithermus profundus DSM 14977     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 759895..770812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCEPR_RS03795 (Ocepr_0753) - 760283..760828 (-) 546 WP_013457380.1 glycerol-3-phosphate acyltransferase -
  OCEPR_RS03800 (Ocepr_0754) - 760831..761241 (-) 411 WP_041553996.1 cobalamin B12-binding domain-containing protein -
  OCEPR_RS03805 (Ocepr_0755) uvrC 761263..763056 (-) 1794 WP_013457382.1 excinuclease ABC subunit UvrC -
  OCEPR_RS03810 (Ocepr_0756) - 764052..764432 (+) 381 WP_013457383.1 NADH-quinone oxidoreductase subunit 15 -
  OCEPR_RS03815 (Ocepr_0757) - 764463..764885 (-) 423 WP_013457384.1 disulfide oxidoreductase -
  OCEPR_RS03820 (Ocepr_0758) pilA 764895..765812 (-) 918 WP_013457385.1 signal recognition particle-docking protein FtsY Machinery gene
  OCEPR_RS03825 (Ocepr_0759) gltX 765809..767260 (-) 1452 WP_013457386.1 glutamate--tRNA ligase -
  OCEPR_RS03830 (Ocepr_0760) - 767496..768785 (+) 1290 WP_013457387.1 ABC transporter substrate-binding protein -
  OCEPR_RS03835 (Ocepr_0761) - 768847..769767 (+) 921 WP_013457388.1 sugar ABC transporter permease -
  OCEPR_RS03840 (Ocepr_0762) - 769767..770612 (+) 846 WP_013457389.1 carbohydrate ABC transporter permease -

Sequence

Protein


Download         Length: 305 a.a.        Molecular weight: 32776.74 Da        Isoelectric Point: 7.3238

>NTDB_id=39115 OCEPR_RS03820 WP_013457385.1 764895..765812(-) (pilA) [Oceanithermus profundus DSM 14977]
MSWFDRLKQGLKKTSQTLTKAVPWGGDPEEVLEELEFALIAADVGLEATQEILKEVRESGKRDLREAVKQALVLQLEPDA
RRAKLRKLGFKPDAKKSTVEPKGHVVLMVGVNGVGKTTTIAKLGRYYKERGKSVLFAAGDTFRAAGGAQLELWGERTGIP
VISAPEGSDPAALAFDAAKARAARGMDLLFVDTAGRLHTKHNLMEELKKVKRSIAKADPGEPGEVWLVLDATTGQNGLEQ
AKKFDEAVGLTGVIVTKLDGTAKGGVLVPIVRELGVPIRFIGVGESAEDLQPFDAGEYVEALLSA

Nucleotide


Download         Length: 918 bp        

>NTDB_id=39115 OCEPR_RS03820 WP_013457385.1 764895..765812(-) (pilA) [Oceanithermus profundus DSM 14977]
ATGAGCTGGTTCGACCGACTGAAGCAGGGGCTCAAGAAGACGAGCCAGACGCTCACCAAGGCGGTCCCCTGGGGCGGCGA
CCCGGAGGAGGTGCTCGAGGAGCTCGAGTTCGCCCTCATCGCCGCCGACGTGGGGCTCGAGGCCACCCAGGAAATCCTGA
AGGAGGTGCGCGAGAGCGGCAAGCGCGACCTGCGCGAAGCGGTCAAGCAGGCGCTGGTGCTGCAGCTCGAGCCCGACGCC
CGCCGCGCCAAGCTGCGCAAGCTGGGCTTCAAGCCCGACGCCAAGAAGAGCACCGTCGAGCCGAAGGGGCACGTCGTCCT
GATGGTCGGCGTCAACGGCGTGGGCAAGACCACCACCATCGCCAAGCTGGGGCGGTACTACAAGGAGCGGGGCAAGAGCG
TCCTCTTCGCCGCCGGCGACACCTTCCGGGCCGCCGGCGGGGCCCAGCTCGAGCTCTGGGGCGAGCGCACCGGCATCCCG
GTGATCAGCGCCCCCGAGGGCTCCGACCCGGCCGCCCTGGCCTTCGACGCCGCCAAGGCCCGCGCCGCCCGCGGGATGGA
CCTGCTCTTCGTGGACACCGCCGGCCGCCTCCACACCAAGCACAACCTGATGGAAGAACTCAAGAAGGTGAAGCGCTCCA
TCGCTAAGGCCGATCCGGGCGAGCCGGGCGAGGTCTGGCTGGTGCTCGACGCCACCACCGGGCAGAACGGCCTGGAGCAG
GCCAAGAAGTTCGACGAGGCGGTCGGGCTCACCGGCGTGATCGTCACCAAGCTCGACGGCACCGCCAAGGGCGGGGTGCT
CGTGCCCATCGTGCGCGAGCTGGGGGTGCCCATCAGGTTCATCGGCGTGGGCGAGAGCGCCGAGGACCTGCAACCCTTTG
ACGCCGGCGAGTACGTGGAGGCGCTGCTGAGCGCGTAG

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(104-303)

SRP54-type protein, helical bundle domain (SRP54_N)

(29-71)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E4U786

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

49.682

100

0.511

Multiple sequence alignment