Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Machinery gene
Locus tag   F7984_RS14430 Genome accession   NZ_CP044545
Coordinates   2998842..2999591 (-) Length   249 a.a.
NCBI ID   WP_066105695.1    Uniprot ID   A0A1B9ART5
Organism   Pradoshia sp. D12     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2993842..3004591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F7984_RS14395 (F7984_14395) radC 2994251..2994940 (-) 690 WP_140461968.1 RadC family protein -
  F7984_RS14400 (F7984_14400) - 2994978..2995586 (-) 609 WP_225983733.1 Maf family protein -
  F7984_RS14405 (F7984_14405) - 2995707..2996663 (-) 957 WP_140461966.1 hypothetical protein -
  F7984_RS14410 (F7984_14410) - 2996759..2997229 (-) 471 WP_140461965.1 type II secretion system protein -
  F7984_RS14415 (F7984_14415) - 2997324..2997824 (-) 501 WP_140461964.1 hypothetical protein -
  F7984_RS14420 (F7984_14420) - 2997856..2998362 (-) 507 WP_077248078.1 hypothetical protein -
  F7984_RS14425 (F7984_14425) pilM 2998332..2998817 (-) 486 WP_140461963.1 type IV pilus biogenesis protein PilM -
  F7984_RS14430 (F7984_14430) comC 2998842..2999591 (-) 750 WP_066105695.1 prepilin peptidase Machinery gene
  F7984_RS14435 (F7984_14435) - 3000200..3001921 (-) 1722 WP_180350012.1 sensor domain-containing diguanylate cyclase -
  F7984_RS14440 (F7984_14440) - 3002060..3003370 (-) 1311 WP_140461962.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 27411.50 Da        Isoelectric Point: 9.3772

>NTDB_id=390922 F7984_RS14430 WP_066105695.1 2998842..2999591(-) (comC) [Pradoshia sp. D12]
MFTLYLLIFLTGLIFGSFYNVVGLRIPAKESIVAPRSACPACGHTLTPIELIPVLSYLFQGGKCRKCKAGISPIYPMMEL
TTAILFMAAPMLLGWTAELFVAWALISLLIIIFISDITYMLIPNKILLFFTVVFLFIRVFIPLDPWWDGIAGAIVGFGIP
FFIAVISKGGMGGGDIKLFGLIGFVMGVKGVILAFIFSTFFGAVFGVIGMLIGLVKRRKPIPFGPFIVVGTLVAYFFGEF
LLDWYLQFL

Nucleotide


Download         Length: 750 bp        

>NTDB_id=390922 F7984_RS14430 WP_066105695.1 2998842..2999591(-) (comC) [Pradoshia sp. D12]
ATGTTTACTCTCTATCTCTTAATCTTCCTCACCGGTCTCATCTTTGGTTCATTTTATAATGTGGTAGGTTTGAGGATTCC
AGCGAAGGAATCGATTGTGGCTCCGAGGTCGGCTTGTCCGGCCTGCGGCCATACATTGACACCGATAGAGCTTATCCCTG
TATTGTCTTACTTGTTTCAAGGGGGGAAGTGCCGTAAGTGTAAGGCGGGCATTTCACCTATTTATCCGATGATGGAACTG
ACAACGGCTATTCTATTTATGGCAGCTCCGATGCTGCTGGGCTGGACTGCTGAATTGTTTGTGGCATGGGCACTTATTTC
CCTGCTGATCATTATTTTTATATCGGATATTACGTACATGCTTATACCGAACAAAATTCTGCTGTTTTTTACAGTTGTTT
TTTTGTTTATTCGGGTATTTATTCCTTTGGACCCATGGTGGGACGGTATAGCTGGGGCTATTGTCGGGTTTGGAATCCCA
TTTTTTATCGCTGTAATCAGCAAAGGCGGCATGGGTGGCGGAGATATTAAATTATTCGGTTTAATTGGATTTGTGATGGG
AGTAAAGGGAGTTATTCTCGCCTTTATATTCTCCACCTTTTTTGGAGCTGTCTTTGGAGTCATTGGGATGTTAATCGGTC
TTGTGAAGCGGCGGAAGCCGATTCCATTTGGACCGTTCATCGTCGTTGGTACACTGGTGGCCTACTTTTTTGGGGAGTTC
TTGCTAGACTGGTATTTACAATTTTTGTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(10-89)

Type IV leader peptidase family (Peptidase_A24)

(104-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B9ART5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Bacillus subtilis subsp. subtilis str. 168

50.622

96.787

0.49

Multiple sequence alignment