Detailed information NTG0390427

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: FSA28_RS02830
• Genome accession: NZ_CP044495
• Coordinates: 564915..567176 (-)
• Length: 753 a.a.
• NCBI ID: WP_002292235.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain UA140
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 559915..572176

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA28_RS02815 (FSA28_0344)	ileS	560415..563207 (+)	2793	WP_002291693.1	isoleucine--tRNA ligase	-
FSA28_RS02820 (FSA28_0345)	-	563980..564282 (-)	303	WP_002263571.1	DUF1827 family protein	-
FSA28_RS02825 (FSA28_0346)	-	564349..564804 (-)	456	WP_002263570.1	NUDIX hydrolase	-
FSA28_RS02830 (FSA28_0347)	clpE	564915..567176 (-)	2262	WP_002292235.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FSA28_RS02835 (FSA28_0348)	argF	567433..568413 (+)	981	WP_002266430.1	ornithine carbamoyltransferase	-
FSA28_RS02840 (FSA28_0349)	-	568490..568720 (+)	231	WP_002263567.1	DUF1797 family protein	-
FSA28_RS02845 (FSA28_0350)	-	568934..569620 (+)	687	WP_002263566.1	amino acid ABC transporter permease	-
FSA28_RS02850 (FSA28_0351)	-	569620..570354 (+)	735	WP_002264702.1	amino acid ABC transporter ATP-binding protein	-
FSA28_RS02855 (FSA28_0352)	-	570547..571023 (+)	477	WP_002263564.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83775.94 Da
• Isoelectric Point: 5.0580

>NTDB_id=390427 FSA28_RS02830 WP_002292235.1 564915..567176(-) (clpE) [Streptococcus mutans strain UA140]
MLCQNCKLNEATIHLYANVNGQQKQIDLCQNCYQIMKTDPENGPLNHLSQQNSSSINPFFDDFFGDLNNFRAFNNQDLPN
TPPTQAGGGNGNGGNNRRPGGPQQQASQKPNGLLEEFGINLTDIARKGEIDPVIGRDEEITRVIEILNRRTKNNPVLIGE
PGVGKTAVVEGLAQKIVDGDVPQKLHGKNVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGS
AGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVAETITILKGIQPKYEDYHHVKYTDE
AIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDHRLIEAENLKAQATRDEDYEKAAYFRDQIVKYKE
MQSAKLDKENTPVITEKNIEVIVEQKTNIPVGELKEKEQSQLIHLADDLKTRVIGQDAAVDKIAKAIRRNRVGLGTPNRP
IGSFLFVGPTGVGKTELSKQLAIELFGSEDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLD
EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEANVGFGASREGRTNSVLGELGNFFSPEFMNR
FDGIIEFQALSKDNLLQIVSLMLDDVNQRLAVNAIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDFYLEH
PDQKELKAIMTSNGKIVIRASNKVETVTKATSD

Nucleotide

• Length: 2262 bp

>NTDB_id=390427 FSA28_RS02830 WP_002292235.1 564915..567176(-) (clpE) [Streptococcus mutans strain UA140]
ATGCTCTGTCAAAATTGTAAATTAAATGAAGCGACTATTCATCTATATGCTAATGTTAATGGTCAGCAAAAGCAGATTGA
CCTTTGTCAAAATTGTTATCAAATTATGAAAACAGATCCTGAAAATGGACCTTTAAATCATCTTTCGCAACAAAATTCAT
CATCCATCAATCCTTTCTTTGATGATTTCTTTGGCGATTTGAATAATTTTCGTGCCTTTAATAATCAAGATCTGCCAAAC
ACACCGCCAACACAAGCTGGCGGCGGCAATGGCAACGGAGGCAATAATCGCCGTCCCGGCGGACCTCAGCAACAGGCCTC
CCAAAAGCCAAATGGGTTGCTTGAAGAGTTTGGTATTAATTTAACAGATATTGCGCGCAAGGGTGAAATTGATCCTGTTA
TTGGCCGTGATGAAGAAATCACAAGGGTTATCGAAATTCTCAACCGTCGCACAAAGAATAATCCTGTTCTTATTGGAGAA
CCGGGTGTCGGTAAAACTGCTGTTGTCGAAGGACTGGCGCAAAAAATTGTTGATGGTGATGTTCCACAAAAATTACATGG
AAAAAATGTCATTCGTCTGGACGTCGTCAGCCTTGTTCAAGGTACTGGTATTCGAGGCCAATTTGAAGAACGGATGCAAA
AGCTAATGGAAGAAATCCGTCAACGTCAAGATGTTATTCTTTTCATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCT
GCTGGCGATGGCAATATGGATGCCGGAAATATTTTAAAACCCGCTTTGGCACGCGGTGAGCTTCAACTTGTTGGTGCTAC
AACACTCAATGAATATCGGATTATTGAAAAAGATGCCGCTTTGGAACGTCGAATGCAACCCGTAAAAGTTGATGAACCTA
GTGTTGCAGAAACCATAACGATTCTTAAAGGTATTCAGCCCAAATATGAAGATTACCATCATGTAAAGTATACAGATGAA
GCGATTGAAGCTGCTGCAAATCTTTCAAATCGTTACATTCAGGATCGTTTTTTACCTGATAAGGCTATTGATCTTCTAGA
TGAAGCTGGCTCTAAAATGAATTTAACACTTAACTTTGTAGATCCTAAAGAAATTGATCACCGCTTGATTGAAGCCGAAA
ATCTAAAAGCTCAAGCAACCCGTGATGAAGATTATGAAAAAGCAGCTTACTTCCGTGATCAAATTGTCAAATACAAGGAA
ATGCAATCCGCTAAACTTGATAAGGAGAATACTCCTGTTATTACAGAAAAAAATATTGAAGTAATTGTCGAGCAAAAGAC
CAATATTCCTGTTGGTGAATTAAAAGAAAAGGAACAATCACAATTAATTCATCTCGCTGACGATCTTAAAACGCGTGTTA
TTGGACAGGATGCTGCTGTTGATAAAATTGCTAAAGCTATTCGCCGCAATCGTGTTGGACTAGGCACTCCAAATCGGCCA
ATTGGTTCTTTCCTTTTTGTCGGCCCTACTGGTGTTGGTAAAACGGAACTCTCTAAACAATTAGCTATTGAGCTTTTTGG
TTCTGAAGATAGTATGATTCGTTTCGATATGAGTGAATACATGGAAAAACATGCTGTGGCTAAACTTGTTGGTGCACCTC
CGGGATATGTCGGTTATGAAGAAGCTGGTCAGTTAACCGAAAAAGTTCGTCGCAACCCTTATTCATTGATCTTACTCGAT
GAAGTTGAAAAAGCTCACCCAGATGTCATGCATATGTTCTTACAAGTGCTTGATGATGGTCGTCTAACGGATGGACAAGG
ACGCACTGTCAGCTTTAAGGATACTATTATTATCATGACCTCAAATGCTGGTACAGGGAAATCTGAAGCTAATGTTGGTT
TTGGTGCCAGTCGAGAAGGCCGTACTAATTCTGTTCTAGGCGAATTGGGTAACTTCTTTAGCCCTGAATTTATGAACCGT
TTTGATGGTATCATCGAATTTCAGGCTTTAAGCAAGGATAATCTTCTTCAAATTGTTTCTCTCATGCTGGATGACGTTAA
TCAACGTTTAGCTGTTAATGCTATTCACCTTGATGTAACTGATAAAGTTAAAGAAAAATTAGTTGATCTCGGTTATGATC
CTAAAATGGGAGCAAGACCGCTGCGTCGTACTATCCAAGAACATATTGAAGATGCTATTACGGATTTCTACTTAGAGCAT
CCTGATCAAAAAGAACTAAAAGCTATTATGACAAGCAACGGCAAAATTGTTATCAGGGCTTCTAACAAAGTCGAGACGGT
TACCAAAGCAACTTCAGATTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (294-391)

• ATPase family associated with various cellular activities (AAA) (AAA) (156-275)

• AAA domain (Cdc48 subfamily) (AAA_2) (479-642)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (650-721)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	99.602	100	0.996
clpE	Streptococcus pneumoniae Rx1	82.487	99.336	0.819
clpE	Streptococcus pneumoniae D39	82.487	99.336	0.819
clpE	Streptococcus pneumoniae R6	82.487	99.336	0.819
clpE	Streptococcus pneumoniae TIGR4	82.487	99.336	0.819
clpC	Lactococcus lactis subsp. cremoris KW2	76.291	100	0.765
clpC	Bacillus subtilis subsp. subtilis str. 168	53.159	86.189	0.458
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48	86.321	0.414
clpC	Streptococcus pneumoniae Rx1	49.194	82.337	0.405
clpC	Streptococcus pneumoniae D39	49.194	82.337	0.405
clpC	Streptococcus pneumoniae TIGR4	49.032	82.337	0.404
clpC	Streptococcus thermophilus LMD-9	47.764	83.134	0.397
clpC	Streptococcus thermophilus LMG 18311	47.444	83.134	0.394
clpC	Streptococcus mutans UA159	47.011	82.205	0.386