Detailed information NTG0390374

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: FSA40_RS06460
• Genome accession: NZ_CP044493
• Coordinates: 1290259..1291152 (+)
• Length: 297 a.a.
• NCBI ID: WP_002279023.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain MD
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1285259..1296152

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA40_RS10550 (FSA40_1292)	-	1287222..1287350 (-)	129	WP_002262718.1	hypothetical protein	-
FSA40_RS10480	-	1287385..1287615 (-)	231	WP_002282891.1	hypothetical protein	-
FSA40_RS06450 (FSA40_1293)	-	1287745..1289496 (-)	1752	WP_002264334.1	GbpC/Spa domain-containing protein	-
FSA40_RS06455 (FSA40_1294)	-	1289659..1289943 (-)	285	WP_002262720.1	helix-turn-helix transcriptional regulator	-
FSA40_RS06460 (FSA40_1295)	irvR	1290259..1291152 (+)	894	WP_002279023.1	LexA family transcriptional regulator IrvR	Regulator
FSA40_RS06465 (FSA40_1296)	csn2-St	1291784..1292833 (-)	1050	WP_151416354.1	CRISPR-associated protein Csn2-St	-
FSA40_RS06470 (FSA40_1297)	cas2	1292830..1293153 (-)	324	WP_002299167.1	CRISPR-associated endonuclease Cas2	-
FSA40_RS06475 (FSA40_1298)	cas1	1293156..1294064 (-)	909	WP_151416355.1	type II CRISPR-associated endonuclease Cas1	-

Sequence

Protein

• Length: 297 a.a.
• Molecular weight: 33639.35 Da
• Isoelectric Point: 6.7036

>NTDB_id=390374 FSA40_RS06460 WP_002279023.1 1290259..1291152(+) (irvR) [Streptococcus mutans strain MD]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTDDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALTVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVIIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide

• Length: 894 bp

>NTDB_id=390374 FSA40_RS06460 WP_002279023.1 1290259..1291152(+) (irvR) [Streptococcus mutans strain MD]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCCACTATCCTTAACATTCCTACAAGTAGTCTTAATGAATATGTTAAAGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTCTCCAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAAGAACAAGATGAAACAGCAAGCTTATCTGCCAGTGATGAAACGACTGATGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATCGCTCTTACTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTATTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (22-70)

• Peptidase S24-like (Peptidase_S24) (184-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	98.99	100	0.99