Detailed information NTG0390359

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: HLG72_RS13095
• Genome accession: NZ_CP053185
• Coordinates: 2630681..2632789 (+)
• Length: 702 a.a.
• NCBI ID: WP_001063329.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain Guangzhou-SAU749
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2625681..2637789

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HLG72_RS13075 (HLG72_13090)	-	2626001..2627281 (-)	1281	WP_001191008.1	hydroxymethylglutaryl-CoA reductase, degradative	-
HLG72_RS13080 (HLG72_13095)	-	2627536..2628702 (+)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
HLG72_RS13085 (HLG72_13100)	sey	2628931..2629596 (-)	666	WP_000644943.1	staphylococcal enterotoxin type Y	-
HLG72_RS13090 (HLG72_13105)	-	2629797..2630318 (-)	522	WP_000262593.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
HLG72_RS13095 (HLG72_13110)	clpE	2630681..2632789 (+)	2109	WP_001063329.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
HLG72_RS13100 (HLG72_13115)	-	2632857..2633027 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
HLG72_RS13105 (HLG72_13120)	feoB	2633040..2635034 (-)	1995	WP_000432888.1	ferrous iron transport protein B	-
HLG72_RS13110 (HLG72_13125)	-	2635046..2635273 (-)	228	WP_000932073.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78094.64 Da
• Isoelectric Point: 4.6626

>NTDB_id=390359 HLG72_RS13095 WP_001063329.1 2630681..2632789(+) (clpE) [Staphylococcus aureus strain Guangzhou-SAU749]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDILENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=390359 HLG72_RS13095 WP_001063329.1 2630681..2632789(+) (clpE) [Staphylococcus aureus strain Guangzhou-SAU749]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
GTCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGAAACAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTGCTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAATGAAATCAAATCTCTACAAGATATATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATTGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGCTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTCCAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGTCCTGAATTCCTTAACCGCTTCAATGGTATTGTAGAATTCTTACACCTAGATAAAG
AGTCACTACAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAGTTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.745	91.595	0.437
clpC	Lactococcus lactis subsp. cremoris KW2	46.203	90.028	0.416
clpE	Streptococcus pneumoniae Rx1	46.992	87.607	0.412
clpE	Streptococcus pneumoniae D39	46.992	87.607	0.412
clpE	Streptococcus pneumoniae R6	46.992	87.607	0.412
clpE	Streptococcus pneumoniae TIGR4	46.992	87.607	0.412
clpC	Bacillus subtilis subsp. subtilis str. 168	43.884	93.162	0.409
clpC	Streptococcus thermophilus LMD-9	44.64	89.031	0.397
clpC	Streptococcus thermophilus LMG 18311	44.48	89.031	0.396
clpC	Streptococcus pneumoniae TIGR4	43.45	89.174	0.387
clpC	Streptococcus pneumoniae D39	43.619	88.177	0.385
clpC	Streptococcus pneumoniae Rx1	43.619	88.177	0.385
clpC	Streptococcus mutans UA159	43.577	87.607	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.894	88.746	0.372