Detailed information NTG0390358

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: FSA40_RS02740
• Genome accession: NZ_CP044493
• Coordinates: 515897..518158 (-)
• Length: 753 a.a.
• NCBI ID: WP_151416201.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain MD
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 510897..523158

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA40_RS02725 (FSA40_0538)	ileS	511391..514183 (+)	2793	WP_002271247.1	isoleucine--tRNA ligase	-
FSA40_RS02730 (FSA40_0539)	-	514962..515264 (-)	303	WP_002263571.1	DUF1827 family protein	-
FSA40_RS02735 (FSA40_0540)	-	515331..515786 (-)	456	WP_002263570.1	NUDIX hydrolase	-
FSA40_RS02740 (FSA40_0541)	clpE	515897..518158 (-)	2262	WP_151416201.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FSA40_RS02745 (FSA40_0542)	argF	518415..519395 (+)	981	WP_002280388.1	ornithine carbamoyltransferase	-
FSA40_RS02750 (FSA40_0543)	-	519472..519702 (+)	231	WP_002263567.1	DUF1797 family protein	-
FSA40_RS02755 (FSA40_0544)	-	519916..520602 (+)	687	WP_002263566.1	amino acid ABC transporter permease	-
FSA40_RS02760 (FSA40_0545)	-	520602..521336 (+)	735	WP_002264702.1	amino acid ABC transporter ATP-binding protein	-
FSA40_RS02765 (FSA40_0546)	-	521529..522005 (+)	477	WP_002263564.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83777.91 Da
• Isoelectric Point: 5.0580

>NTDB_id=390358 FSA40_RS02740 WP_151416201.1 515897..518158(-) (clpE) [Streptococcus mutans strain MD]
MLCQNCKLNEATIHLYTNVNGQQKQIDLCQNCYQIMKTDPENGPLNHLSQQNSSSINPFFDDFFGDLNNFRAFNNQDLPN
TPPTQAGGGNGNGGNNRRPGGPQQQASQKPNGLLEEFGINLTDIARKGEIDPVIGRDEEITRVIEILNRRTKNNPVLIGE
PGVGKTAVVEGLAQKIVDGDVPQKLHGKNVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGS
AGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVAETITILKGIQPKYEDYHHVKYTDE
AIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDHRLIEAENLKAQATRDEDYEKAAYFRDQIAKYKE
MQSAKLDKENTPVITEKNIEVIVEQKTNIPVGELKEKEQSQLIHLADDLKTRVIGQDAAVDKIAKAIRRNRVGLGTPNRP
IGSFLFVGPTGVGKTELSKQLAIELFGSEDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLD
EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEANVGFGASREGRTNSVLGELGNFFSPEFMNR
FDGIIEFQALSKDNLLQIVSLMLDDVNQRLAVNAIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDFYLEH
PDQKELKAIMTSNGKIVIRASNKVETVTKATSD

Nucleotide

• Length: 2262 bp

>NTDB_id=390358 FSA40_RS02740 WP_151416201.1 515897..518158(-) (clpE) [Streptococcus mutans strain MD]
ATGCTCTGTCAAAATTGTAAATTAAATGAAGCGACTATTCATCTATATACTAATGTTAATGGTCAGCAAAAGCAGATTGA
CCTTTGTCAAAATTGTTATCAAATTATGAAAACAGATCCTGAAAATGGACCTTTAAATCATCTTTCGCAACAAAATTCGT
CATCCATCAATCCTTTCTTTGATGATTTCTTTGGCGATTTGAATAATTTTCGTGCCTTTAATAATCAAGATCTGCCAAAC
ACACCGCCAACACAAGCTGGCGGCGGCAATGGTAACGGAGGCAATAATCGCCGTCCCGGCGGACCTCAGCAACAGGCCTC
CCAAAAGCCAAATGGGTTGCTTGAAGAGTTTGGTATTAATTTAACAGATATTGCGCGCAAGGGTGAAATTGATCCTGTTA
TTGGCCGTGATGAAGAAATCACAAGGGTTATCGAAATTCTCAACCGTCGCACAAAGAATAATCCTGTTCTTATTGGAGAA
CCGGGTGTCGGTAAAACTGCTGTTGTCGAAGGACTGGCGCAAAAAATTGTTGATGGTGATGTTCCACAAAAATTACATGG
AAAAAATGTCATTCGTCTGGACGTCGTCAGCCTTGTTCAAGGTACTGGTATTCGAGGCCAATTTGAAGAACGGATGCAAA
AGCTAATGGAAGAAATCCGTCAACGTCAAGATGTTATTCTTTTCATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCT
GCTGGCGATGGCAATATGGACGCCGGAAATATTTTAAAACCCGCTTTGGCACGCGGTGAGCTTCAACTTGTTGGTGCTAC
AACACTCAATGAATATCGGATTATTGAAAAAGATGCCGCTTTGGAACGTCGAATGCAACCCGTAAAAGTTGATGAACCTA
GTGTTGCAGAAACCATAACGATTCTTAAAGGTATTCAGCCCAAATATGAAGATTACCATCATGTAAAGTATACAGATGAA
GCGATTGAAGCTGCTGCAAATCTTTCAAATCGTTACATTCAGGATCGTTTTTTACCTGATAAGGCTATTGATCTTCTAGA
TGAAGCTGGCTCTAAAATGAATTTAACACTTAACTTTGTAGATCCTAAAGAAATTGATCACCGCTTGATTGAAGCCGAAA
ATCTAAAAGCTCAAGCAACCCGTGATGAAGATTATGAAAAAGCAGCTTACTTCCGTGATCAAATTGCCAAATACAAGGAA
ATGCAATCCGCTAAACTTGATAAGGAGAATACTCCTGTTATTACAGAAAAAAATATTGAAGTAATTGTCGAGCAAAAGAC
CAATATTCCTGTTGGTGAATTAAAAGAAAAGGAACAATCACAATTAATTCATCTCGCTGACGATCTTAAAACGCGTGTTA
TTGGACAGGATGCTGCTGTTGATAAAATTGCTAAAGCTATTCGCCGCAATCGTGTTGGACTAGGCACTCCAAATCGGCCA
ATTGGTTCTTTCCTTTTTGTCGGCCCTACTGGTGTTGGTAAAACGGAACTCTCTAAACAATTAGCTATTGAGCTTTTTGG
TTCTGAAGATAGTATGATTCGTTTCGATATGAGTGAATACATGGAAAAACATGCTGTGGCTAAACTTGTTGGTGCACCTC
CGGGATATGTCGGTTATGAAGAAGCTGGTCAGTTAACCGAAAAAGTTCGTCGCAATCCTTATTCATTGATCTTACTCGAT
GAAGTTGAAAAAGCTCATCCAGATGTCATGCATATGTTCTTACAAGTGCTTGATGATGGCCGTCTAACGGATGGACAAGG
ACGCACTGTCAGCTTTAAGGATACTATTATTATCATGACCTCAAATGCTGGTACAGGGAAATCTGAAGCTAATGTTGGTT
TTGGTGCCAGTCGAGAAGGCCGTACTAATTCTGTTCTAGGCGAATTGGGTAACTTCTTTAGCCCTGAATTTATGAACCGT
TTTGATGGTATCATCGAATTTCAGGCTTTAAGCAAGGATAATCTTCTTCAAATTGTTTCTCTCATGCTGGATGACGTTAA
TCAACGTTTAGCTGTTAATGCTATTCACCTTGATGTAACTGATAAAGTTAAAGAAAAATTGGTTGATCTCGGTTATGATC
CTAAAATGGGAGCAAGACCGCTGCGTCGTACTATCCAAGAACATATTGAAGATGCTATTACGGATTTCTACTTAGAGCAT
CCTGATCAAAAAGAACTAAAAGCTATTATGACAAGCAACGGCAAAATTGTTATCAGGGCTTCTAACAAAGTCGAAACGGT
TACCAAAGCAACTTCAGATTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (479-642)

• AAA lid domain (AAA_lid_9) (294-391)

• ATPase family associated with various cellular activities (AAA) (AAA) (156-275)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (650-721)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	99.602	100	0.996
clpE	Streptococcus pneumoniae Rx1	82.754	99.336	0.822
clpE	Streptococcus pneumoniae D39	82.754	99.336	0.822
clpE	Streptococcus pneumoniae R6	82.754	99.336	0.822
clpE	Streptococcus pneumoniae TIGR4	82.754	99.336	0.822
clpC	Lactococcus lactis subsp. cremoris KW2	76.424	100	0.766
clpC	Bacillus subtilis subsp. subtilis str. 168	53.159	86.189	0.458
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48	86.321	0.414
clpC	Streptococcus pneumoniae Rx1	49.355	82.337	0.406
clpC	Streptococcus pneumoniae D39	49.355	82.337	0.406
clpC	Streptococcus pneumoniae TIGR4	49.194	82.337	0.405
clpC	Streptococcus thermophilus LMD-9	47.764	83.134	0.397
clpC	Streptococcus thermophilus LMG 18311	47.444	83.134	0.394
clpC	Streptococcus mutans UA159	47.011	82.205	0.386