Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   FSA31_RS08645 Genome accession   NZ_CP044492
Coordinates   1726592..1727917 (-) Length   441 a.a.
NCBI ID   WP_002284746.1    Uniprot ID   -
Organism   Streptococcus mutans strain T8     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1721592..1732917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS08610 (FSA31_1705) - 1722337..1723279 (+) 943 Protein_1608 HlyD family efflux transporter periplasmic adaptor subunit -
  FSA31_RS08615 (FSA31_1706) - 1723540..1723683 (-) 144 WP_002263740.1 hypothetical protein -
  FSA31_RS08625 (FSA31_1707) - 1723975..1724997 (-) 1023 WP_002284748.1 thioredoxin family protein -
  FSA31_RS08630 (FSA31_1708) - 1725478..1725666 (-) 189 WP_002284747.1 Blp family class II bacteriocin -
  FSA31_RS08635 (FSA31_1709) - 1725834..1726043 (-) 210 WP_002268232.1 Blp family class II bacteriocin -
  FSA31_RS08640 (FSA31_1710) comC/blpC 1726310..1726450 (+) 141 WP_002270250.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  FSA31_RS08645 (FSA31_1711) comD/blpH 1726592..1727917 (-) 1326 WP_002284746.1 GHKL domain-containing protein Regulator
  FSA31_RS08650 (FSA31_1712) comE/blpR 1727914..1728666 (-) 753 WP_002284745.1 response regulator transcription factor Regulator
  FSA31_RS08655 (FSA31_1713) - 1729131..1729769 (-) 639 WP_002262115.1 VTT domain-containing protein -
  FSA31_RS08660 (FSA31_1714) - 1729817..1730443 (-) 627 WP_002268642.1 hypothetical protein -
  FSA31_RS08665 (FSA31_1715) der 1730518..1731828 (-) 1311 WP_002262117.1 ribosome biogenesis GTPase Der -
  FSA31_RS08670 (FSA31_1716) dnaI 1731841..1732740 (-) 900 WP_002284744.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50556.77 Da        Isoelectric Point: 9.8155

>NTDB_id=390318 FSA31_RS08645 WP_002284746.1 1726592..1727917(-) (comD/blpH) [Streptococcus mutans strain T8]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIVLSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGNQGIVMDSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQALYIIESYNVMPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSGKIQLPDMELLDFITILSILCDNAIEAALESLKPEIQLAFFKKNGSIVFIIQNSSKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLIMK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=390318 FSA31_RS08645 WP_002284746.1 1726592..1727917(-) (comD/blpH) [Streptococcus mutans strain T8]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTAAATGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGTTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAAATCAAGGAATTGTAATGGACAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTAAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATCCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGCATTGTATATTATAGAGAGTTATAATGTGATGCC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTATCAGCAAAAATCTTAGAAGCTCAAAATAAA
AAAATTGCTGTCAATGTAGAGGTCTCAGGTAAAATACAGCTGCCTGATATGGAGTTGCTTGATTTCATTACTATACTTTC
TATCTTGTGCGATAATGCTATTGAGGCCGCTCTCGAATCACTAAAACCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGCATAGTCTTTATCATCCAGAATTCCTCCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAGTCATCATCATTTATTCAAGCAACTCCTAATAATGAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

97.052

100

0.971

Multiple sequence alignment