Detailed information    

insolico Bioinformatically predicted

Overview

Name   hns   Type   Regulator
Locus tag   FSC02_RS01325 Genome accession   NZ_CP044445
Coordinates   282197..282523 (+) Length   108 a.a.
NCBI ID   WP_075167809.1    Uniprot ID   A0A7S7AEC3
Organism   Acinetobacter indicus strain CMG3-2     
Function   repress the expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 268861..282051 282197..282523 flank 146


Gene organization within MGE regions


Location: 268861..282523
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSC02_RS01255 (FSC02_01280) tnpA 268861..269310 (-) 450 WP_016659780.1 IS200/IS605 family transposase -
  FSC02_RS01260 (FSC02_01285) - 269383..270774 (+) 1392 WP_016658436.1 RNA-guided endonuclease InsQ/TnpB family protein -
  FSC02_RS01265 (FSC02_01295) - 270907..271649 (+) 743 Protein_242 IS3 family transposase -
  FSC02_RS01270 (FSC02_01305) ltrA 272154..273395 (+) 1242 WP_163169929.1 group II intron reverse transcriptase/maturase -
  FSC02_RS01275 (FSC02_01310) - 273475..273960 (+) 486 Protein_244 IS3 family transposase -
  FSC02_RS01280 (FSC02_01315) - 274105..274374 (-) 270 WP_005181625.1 oxidative damage protection protein -
  FSC02_RS01285 (FSC02_01320) argH 274396..275826 (-) 1431 WP_171457075.1 argininosuccinate lyase -
  FSC02_RS01290 (FSC02_01325) - 275817..276971 (+) 1155 WP_104989206.1 sensor histidine kinase -
  FSC02_RS01295 (FSC02_01330) - 277027..277767 (+) 741 WP_127799612.1 LytR/AlgR family response regulator transcription factor -
  FSC02_RS01300 (FSC02_01335) hemC 277876..278793 (+) 918 WP_034598116.1 hydroxymethylbilane synthase -
  FSC02_RS01305 (FSC02_01340) - 278795..279574 (+) 780 WP_127799614.1 uroporphyrinogen-III synthase -
  FSC02_RS01310 (FSC02_01345) - 279571..280416 (+) 846 WP_127799616.1 hypothetical protein -
  FSC02_RS01315 (FSC02_01350) - 280419..281612 (+) 1194 WP_127799618.1 heme biosynthesis protein HemY -
  FSC02_RS01320 (FSC02_01355) - 281623..282051 (+) 429 WP_005181644.1 acyl-CoA thioesterase -
  FSC02_RS01325 (FSC02_01360) hns 282197..282523 (+) 327 WP_075167809.1 H-NS family nucleoid-associated regulatory protein Regulator

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12271.00 Da        Isoelectric Point: 8.4694

>NTDB_id=390033 FSC02_RS01325 WP_075167809.1 282197..282523(+) (hns) [Acinetobacter indicus strain CMG3-2]
MMPDISNLSVEQLKRLQEEAEALIASKKDQAVEDAYNQILAIAENAGLSIEQILEFGASKRKKNVRKSVEPRYRNKTNAN
ETWTGRGKQPRWLVAELEKGAKLEDFLI

Nucleotide


Download         Length: 327 bp        

>NTDB_id=390033 FSC02_RS01325 WP_075167809.1 282197..282523(+) (hns) [Acinetobacter indicus strain CMG3-2]
ATGATGCCCGATATTAGTAATTTGTCTGTAGAACAATTAAAGCGCTTGCAGGAAGAAGCGGAAGCATTAATTGCATCGAA
AAAGGACCAGGCAGTTGAAGATGCATATAATCAGATTTTGGCAATTGCTGAAAATGCGGGTTTAAGCATTGAACAGATTC
TTGAGTTTGGTGCGTCTAAACGTAAAAAGAATGTACGTAAATCGGTAGAGCCGCGTTATCGTAATAAAACCAATGCCAAT
GAAACCTGGACAGGTCGTGGTAAGCAACCGCGCTGGTTAGTGGCAGAACTGGAAAAAGGTGCCAAGCTTGAAGACTTCTT
GATCTAA

Domains

Predicted by InterproScan.

H-NS histone family (Histone_HNS)

(12-102)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7S7AEC3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hns Acinetobacter baumannii strain A118

85.185

100

0.852

Multiple sequence alignment