Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   HLB22_RS04415 Genome accession   NZ_CP053101
Coordinates   940682..942490 (+) Length   602 a.a.
NCBI ID   WP_000082725.1    Uniprot ID   A0A2K4AK92
Organism   Staphylococcus aureus strain EDCC5398     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 935682..947490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLB22_RS04390 (HLB22_04390) trpS 936016..937005 (-) 990 WP_000448941.1 tryptophan--tRNA ligase -
  HLB22_RS04395 (HLB22_04395) spxA 937300..937695 (+) 396 WP_000258001.1 transcriptional regulator SpxA -
  HLB22_RS04400 (HLB22_04400) tnpA 937907..938392 (+) 486 WP_000093392.1 IS200/IS605 family transposase -
  HLB22_RS04405 (HLB22_04405) mecA 938808..939527 (+) 720 WP_001217724.1 adaptor protein MecA -
  HLB22_RS04410 (HLB22_04410) coiA 939648..940634 (+) 987 WP_170267418.1 competence protein CoiA family protein Machinery gene
  HLB22_RS04415 (HLB22_04415) pepF 940682..942490 (+) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  HLB22_RS04420 (HLB22_04420) yjbH 942950..943756 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  HLB22_RS04425 (HLB22_04425) - 943779..944144 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -
  HLB22_RS04430 (HLB22_04430) - 944248..944841 (-) 594 WP_000224621.1 CYTH domain-containing protein -
  HLB22_RS04435 (HLB22_04435) - 945027..945374 (+) 348 WP_001242102.1 hypothetical protein -
  HLB22_RS04440 (HLB22_04440) - 945391..946026 (+) 636 WP_001077683.1 GTP pyrophosphokinase family protein -
  HLB22_RS04445 (HLB22_04445) - 946043..946852 (+) 810 WP_001270834.1 NAD kinase -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69805.37 Da        Isoelectric Point: 4.9226

>NTDB_id=389879 HLB22_RS04415 WP_000082725.1 940682..942490(+) (pepF) [Staphylococcus aureus strain EDCC5398]
MSQQLSREEQERKYPEYTWDLTTIFKDDEAFEAAFKEVENELGKEEQFKGHIGDSAETLYNALELEDTLGTKLEKVYVYA
HLKQDQDTTNDKYTGMESRAHQLIIKFSSAWSFLVPEILQIDEDKIQSFVNSYDKLQKFAFDLKLINEKRPHILDAETEK
LLTEAQDALSTPSNVYGMFSNADLVFEDAIDKDGNAHPLTQGTFIKYLESDDRKLRESAFRNVYKAYGAHNNTLGATLAG
EVKKNVFNARTHNYKTAREKALSNNHIPENVYDNLVKTVHKYLPLLHRYTELRKELLGLDDLKMYDLYTPLIKDIKFEMP
YEEAKEWMLKALEPMGEEYLNVVKEGLNNRWVDVYENKGKRSGGYSSGAHLTNPFILLNWSNTISDLYTLVHEFGHSAHS
YFSRKFQPSNSSDYTIFVAEVASTCNEALLSDYMDKHLDDEKRLLLLNQELERFRATLFRQTMFAEFEHKIHAIEEAGEP
LTPTRMNEEYAKLNKLYFGDSVETDEDISKEWSRIPHFYMNYYVYQYATGYSAAQSLSHQILTEGKPAVDRYINEFLKKG
SSNYPIEILKNAGVDMTTPEPIEQACEVFEQKLNAFEKLMKA

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=389879 HLB22_RS04415 WP_000082725.1 940682..942490(+) (pepF) [Staphylococcus aureus strain EDCC5398]
ATGAGTCAACAATTATCGAGAGAAGAACAGGAACGTAAATATCCTGAATATACATGGGACTTAACAACAATTTTCAAAGA
TGATGAAGCTTTTGAGGCTGCATTTAAAGAAGTTGAAAATGAGTTAGGCAAAGAAGAACAATTTAAAGGACACATTGGTG
ATAGTGCTGAGACATTATACAATGCGTTAGAATTAGAAGATACATTAGGTACTAAATTAGAAAAAGTATATGTATACGCG
CACCTAAAACAAGACCAAGATACAACGAACGACAAGTATACTGGTATGGAGTCAAGAGCACATCAATTAATTATTAAATT
TAGCTCGGCATGGAGTTTCTTAGTGCCAGAGATTTTACAAATTGATGAAGATAAAATTCAATCATTTGTAAATTCATATG
ATAAATTACAAAAATTCGCATTTGATTTGAAGTTGATTAATGAAAAACGTCCTCATATTTTAGATGCTGAAACTGAAAAG
TTATTAACAGAAGCGCAGGACGCGTTATCAACGCCATCAAATGTATACGGTATGTTTAGCAACGCTGATTTAGTATTTGA
AGATGCGATTGATAAAGATGGAAATGCACACCCGTTAACACAAGGTACATTTATTAAGTATTTAGAATCAGATGATCGCA
AACTAAGAGAAAGTGCTTTTAGAAATGTATATAAAGCATATGGTGCTCATAATAATACGCTTGGCGCTACACTAGCAGGT
GAAGTGAAGAAAAATGTATTTAATGCTCGTACACACAATTACAAAACTGCAAGAGAAAAAGCATTGAGTAATAATCATAT
TCCAGAAAATGTATATGACAATCTAGTAAAAACTGTACATAAATATTTACCATTGCTACATAGATATACTGAATTGCGCA
AAGAATTGCTAGGTTTAGATGACTTGAAAATGTATGATTTATATACACCATTAATTAAAGATATTAAGTTTGAAATGCCT
TATGAAGAAGCTAAAGAGTGGATGTTAAAAGCATTAGAACCAATGGGTGAAGAATATTTAAATGTAGTTAAAGAAGGCTT
AAACAATCGTTGGGTCGATGTCTATGAGAATAAAGGTAAACGTTCAGGTGGCTATTCATCAGGTGCACATTTAACTAATC
CATTTATTCTACTTAACTGGTCTAATACTATTTCAGACTTATACACATTAGTTCATGAATTTGGGCATTCAGCACATAGT
TACTTCAGTAGAAAATTCCAACCGTCAAATTCTAGTGACTACACTATTTTTGTCGCTGAAGTTGCATCAACTTGTAACGA
AGCACTTTTAAGTGATTATATGGATAAACATCTTGATGATGAAAAACGCTTATTATTATTAAACCAAGAATTAGAACGTT
TCAGAGCTACATTATTCCGACAAACAATGTTCGCAGAATTTGAGCATAAAATTCATGCAATTGAAGAAGCAGGTGAACCA
TTAACGCCAACTAGAATGAATGAAGAATATGCCAAATTAAATAAATTATACTTCGGTGATTCTGTAGAAACTGATGAAGA
TATTAGTAAGGAATGGTCACGTATTCCACACTTCTATATGAATTATTATGTATATCAATACGCAACTGGTTACAGTGCAG
CTCAAAGCTTAAGTCATCAAATTTTAACAGAAGGTAAGCCAGCAGTAGATAGATATATTAATGAATTCTTGAAAAAAGGT
AGCTCAAATTATCCAATTGAGATATTAAAAAATGCTGGTGTAGATATGACAACACCTGAACCAATTGAACAAGCTTGTGA
AGTTTTTGAACAAAAATTGAACGCTTTTGAAAAATTAATGAAAGCTTAG

Domains

Predicted by InterProScan.

Peptidase family M3 (Peptidase_M3)

(207-587)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K4AK92

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

43.952

97.508

0.429