Detailed information NTG0038987

Bioinformatically predicted

Overview

• Name: pepF
• Type: Regulator
• Locus tag: LDBND_RS09635
• Genome accession: NC_014727
• Coordinates: 1927566..1929368 (+)
• Length: 600 a.a.
• NCBI ID: WP_013440239.1
• Uniprot ID: -
• Organism: Lactobacillus delbrueckii subsp. bulgaricus ND02
• Function: degradation of XIP; competence shut-off (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1907906..1929368	1927566..1929368	within	0

Gene organization within MGE regions

Location: 1907906..1929368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LDBND_RS09535 (LDBND_1856)	-	1907906..1908664 (-)	759	WP_013440222.1	C40 family peptidase	-
LDBND_RS09540 (LDBND_1857)	-	1908960..1909673 (-)	714	WP_013440223.1	C40 family peptidase	-
LDBND_RS09545 (LDBND_1858)	-	1909827..1910609 (-)	783	WP_013440224.1	C40 family peptidase	-
LDBND_RS09550 (LDBND_1859)	-	1910799..1911272 (-)	474	WP_013440225.1	C40 family peptidase	-
LDBND_RS09555 (LDBND_1860)	-	1911442..1912488 (-)	1047	WP_013440226.1	2-hydroxyacid dehydrogenase	-
LDBND_RS09560 (LDBND_1861)	-	1912772..1913257 (-)	486	WP_013440227.1	C40 family peptidase	-
LDBND_RS09565 (LDBND_1862)	-	1913382..1913924 (-)	543	WP_003611236.1	guanylate kinase	-
LDBND_RS09570 (LDBND_1863)	-	1914014..1914352 (+)	339	WP_013440228.1	DUF2187 family protein	-
LDBND_RS09575 (LDBND_1864)	-	1914416..1915954 (+)	1539	WP_013440229.1	O-antigen ligase family protein	-
LDBND_RS09580 (LDBND_1865)	-	1916007..1916633 (-)	627	WP_013440230.1	LVIS_2131 family protein	-
LDBND_RS09585 (LDBND_1866)	-	1916636..1917151 (-)	516	WP_002879488.1	hypothetical protein	-
LDBND_RS09590 (LDBND_1867)	-	1917705..1918373 (+)	669	WP_013440231.1	IS607 family transposase	-
LDBND_RS09595 (LDBND_1868)	-	1918342..1920048 (+)	1707	WP_013440232.1	RNA-guided endonuclease TnpB family protein	-
LDBND_RS09600 (LDBND_1869)	-	1920450..1920884 (+)	435	WP_180754090.1	hypothetical protein	-
LDBND_RS09605 (LDBND_1870)	-	1921110..1921601 (-)	492	WP_013440234.1	threonine/serine exporter family protein	-
LDBND_RS09610 (LDBND_1871)	-	1921604..1922359 (-)	756	WP_041812005.1	threonine/serine exporter family protein	-
LDBND_RS09615 (LDBND_1872)	-	1922412..1923956 (-)	1545	WP_013440236.1	ABC-F family ATP-binding cassette domain-containing protein	-
LDBND_RS09620 (LDBND_1873)	-	1923971..1924348 (-)	378	WP_002879494.1	hypothetical protein	-
LDBND_RS09625 (LDBND_1874)	-	1924467..1925606 (-)	1140	WP_013440237.1	LCP family protein	-
LDBND_RS09630 (LDBND_1875)	-	1925946..1927244 (+)	1299	WP_013440238.1	RNA-guided endonuclease InsQ/TnpB family protein	-
LDBND_RS09635 (LDBND_1876)	pepF	1927566..1929368 (+)	1803	WP_013440239.1	oligoendopeptidase F	Regulator

Sequence

Protein

• Length: 600 a.a.
• Molecular weight: 68270.11 Da
• Isoelectric Point: 4.4788

>NTDB_id=38987 LDBND_RS09635 WP_013440239.1 1927566..1929368(+) (pepF) [Lactobacillus delbrueckii subsp. bulgaricus ND02]
MEIPYRSEVPKEQTWDLTRIFKTEADWEAAFKAVKQEVKALPALEDGFTESAAVLYDRLTQIFAVDRRLSKIYVYASMAS
DVDTSNQKKLALNSRAQSLAAEYQAAVAFIQPAVLALGKEGLDAFFKEEPRLENYRHYLEQIVKQEEHVLPAEEEKLVSA
AGDALSASANTFNVLTNSDLQFPYIEGEDGEAVELTEANYDILIQSQNREVREDAFDALYAVYGQFASTFASTLAGNVKA
HNFDAQTHHYQDALAAALSENNIPVDVYNQLLTSVHKHLDLLHRYVNLREEILDLKGDLQMWDMYVPITGKPSLSYTFAE
AKAQAREALQVLGEDYVKHVDYLFNNRCIDHVANMHKQSGAYSGGAYDTDAYELLNWQGDLDSLYTLVHETGHSVHSMYT
RENQPYVYGDYPIFVAEIASTTNENLLTNYFLDRVTDPKTRAFLLNYYLSSFKGTVYRQTQFAEFEKFIHESDQAGEALT
ADYLCGFYDRLNQQYYGPAISLGSDIDLEWARIPHFYYNFYVYQYATGFAAATALANKITYGSQEDKEKYLDFLKSGSSD
YPINIMQKAGVDMTKSDYLEDAFKVFAERLDEFTDLIKKL

Nucleotide

• Length: 1803 bp

>NTDB_id=38987 LDBND_RS09635 WP_013440239.1 1927566..1929368(+) (pepF) [Lactobacillus delbrueckii subsp. bulgaricus ND02]
ATGGAAATCCCTTATCGCAGTGAGGTTCCCAAAGAACAGACCTGGGACTTGACCCGGATCTTCAAGACTGAGGCGGACTG
GGAGGCCGCCTTTAAAGCTGTCAAGCAGGAAGTCAAGGCCCTGCCGGCCTTGGAAGACGGCTTTACGGAGAGCGCGGCCG
TCCTCTATGACCGCTTGACCCAGATTTTTGCCGTTGACCGCCGCCTGTCCAAGATCTACGTCTATGCCAGCATGGCCAGC
GACGTCGACACCAGCAACCAGAAGAAGCTGGCCCTCAATTCCCGCGCCCAGAGCCTGGCCGCTGAATACCAGGCGGCTGT
TGCCTTCATTCAGCCGGCTGTTTTAGCCTTGGGGAAAGAGGGCCTGGACGCCTTTTTCAAGGAAGAGCCAAGACTGGAAA
ACTACCGGCACTATTTGGAACAGATCGTCAAGCAGGAAGAGCACGTTTTGCCAGCTGAAGAGGAGAAGCTGGTATCGGCG
GCCGGGGATGCCCTGTCAGCTTCGGCCAACACCTTCAACGTCTTGACCAACTCCGATTTGCAATTCCCTTACATTGAAGG
TGAAGACGGGGAAGCAGTGGAACTGACGGAAGCCAACTATGACATCTTGATCCAGTCCCAGAACCGGGAAGTCAGAGAGG
ACGCCTTTGACGCCCTTTACGCTGTCTACGGCCAGTTCGCGTCAACTTTTGCCTCAACCTTGGCCGGCAATGTCAAGGCC
CACAACTTTGATGCCCAGACCCACCACTACCAGGACGCCTTAGCCGCGGCTCTGTCAGAAAACAACATCCCTGTCGACGT
CTACAACCAGCTTTTGACTAGCGTCCACAAGCACCTGGACCTCCTCCACCGCTATGTCAACTTGCGCGAAGAGATCCTGG
ACCTGAAGGGCGACCTGCAAATGTGGGACATGTACGTGCCGATCACGGGCAAGCCAAGCCTCAGCTACACTTTCGCTGAA
GCCAAGGCCCAGGCCAGAGAGGCCCTGCAGGTTTTGGGCGAGGACTATGTCAAACACGTCGACTACCTCTTCAATAACCG
CTGCATCGACCACGTGGCTAACATGCACAAGCAAAGCGGGGCCTACTCCGGCGGGGCTTATGACACCGACGCCTATGAGC
TCTTGAACTGGCAGGGGGACCTGGATTCCCTCTACACCCTGGTCCACGAGACCGGCCACTCAGTCCACAGCATGTACACC
CGGGAAAACCAGCCATACGTGTACGGGGACTATCCGATCTTTGTCGCGGAAATTGCCTCAACGACCAATGAAAACCTGCT
GACCAACTACTTCCTGGATCGGGTGACGGATCCAAAGACCCGGGCCTTCCTGCTCAACTACTACTTGAGCTCCTTTAAGG
GAACGGTCTACCGGCAGACCCAGTTCGCGGAATTCGAGAAGTTCATTCATGAAAGCGACCAGGCGGGTGAAGCCTTGACG
GCTGACTACCTGTGTGGCTTCTACGACCGGCTCAACCAGCAGTACTACGGCCCGGCGATCAGCCTGGGCAGCGACATCGA
CCTGGAATGGGCCCGGATTCCTCACTTCTATTACAACTTCTACGTCTACCAGTACGCGACCGGCTTTGCCGCGGCGACTG
CCCTGGCTAACAAGATTACTTACGGCAGCCAGGAAGACAAGGAGAAGTACCTGGACTTCCTTAAGTCCGGCTCCAGCGAC
TACCCGATCAACATCATGCAGAAGGCCGGCGTCGACATGACCAAGTCCGACTACCTGGAAGATGCCTTCAAGGTCTTTGC
GGAAAGACTGGACGAATTTACTGACTTAATCAAAAAATTGTAG

Domains

Predicted by InterproScan.

• Peptidase family M3 (Peptidase_M3) (203-584)

• Oligopeptidase F (Peptidase_M3_N) (115-182)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pepF	Streptococcus salivarius strain HSISS4	50	99	0.495