Detailed information NTG0388983

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: LPB220_RS03265
• Genome accession: NZ_CP044230
• Coordinates: 605368..607626 (-)
• Length: 752 a.a.
• NCBI ID: WP_049498371.1
• Uniprot ID: -
• Organism: Streptococcus sp. LPB0220
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 600368..612626

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPB220_RS03245 (LPB220_03245)	ileS	601389..604181 (+)	2793	WP_150905506.1	isoleucine--tRNA ligase	-
LPB220_RS03250 (LPB220_03250)	-	604284..604586 (-)	303	WP_003012157.1	DUF1827 family protein	-
LPB220_RS03255 (LPB220_03255)	-	604654..605103 (-)	450	WP_049474218.1	NUDIX hydrolase	-
LPB220_RS03265 (LPB220_03265)	clpE	605368..607626 (-)	2259	WP_049498371.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LPB220_RS03270 (LPB220_03270)	-	607874..608104 (+)	231	WP_003005989.1	DUF1797 family protein	-
LPB220_RS03275 (LPB220_03275)	-	608270..609124 (+)	855	WP_041826248.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
LPB220_RS03280 (LPB220_03280)	-	609138..609911 (+)	774	WP_049487481.1	HAD-IIB family hydrolase	-
LPB220_RS03285 (LPB220_03285)	-	609964..610842 (+)	879	WP_049474222.1	NAD(P)H-hydrate dehydratase	-
LPB220_RS03290 (LPB220_03290)	-	610869..611864 (+)	996	WP_049474223.1	LacI family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 752 a.a.
• Molecular weight: 83779.95 Da
• Isoelectric Point: 5.2208

>NTDB_id=388983 LPB220_RS03265 WP_049498371.1 605368..607626(-) (clpE) [Streptococcus sp. LPB0220]
MLCQNCKINESTIHLYTNVNGRQQQVDLCQNCYKIMKTDPNNSFLKGMTQRSQLTGDPFEDFFNNLGNFQSPQEPQTPPT
QSGGSYGGGGYGQNNNRGGGQDPRQARPQKPKGLLEEFGINVTEIARKGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRQREDVILFIDEIHEIVGAG
SAGEGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHYTD
GAIEAAAILSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYK
EMQGQHVTDQETPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGSPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLVLL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSVLGELGNFFSPEFMN
RFDGIIEFQPLSKENLLQIVTLMLDEVNQRLAQNEIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDYYLE
HPSEKQLKAVMTSNGNISIKAVHKTAEKKSEA

Nucleotide

• Length: 2259 bp

>NTDB_id=388983 LPB220_RS03265 WP_049498371.1 605368..607626(-) (clpE) [Streptococcus sp. LPB0220]
ATGCTTTGTCAAAATTGTAAAATAAATGAATCAACCATCCATTTATATACAAATGTAAATGGACGTCAGCAGCAAGTAGA
CCTCTGTCAAAATTGCTATAAAATTATGAAAACAGACCCAAATAACAGCTTCTTGAAAGGCATGACCCAACGGAGCCAAC
TCACTGGAGATCCTTTTGAAGATTTCTTCAATAACCTTGGAAACTTCCAAAGTCCGCAAGAACCTCAAACCCCTCCAACT
CAATCCGGAGGCAGTTATGGAGGTGGCGGCTACGGCCAAAACAATAACCGTGGTGGCGGTCAAGACCCTCGTCAAGCACG
CCCTCAGAAGCCAAAAGGACTGTTAGAAGAGTTCGGTATCAATGTCACAGAAATTGCCCGCAAAGGGGATATTGACCCTG
TCATTGGCCGTGACGAGGAGATTATCCGTGTCATCGAAATTCTCAACCGTCGAACCAAGAACAATCCGGTTCTGATTGGA
GAGCCTGGGGTCGGAAAAACTGCTGTTGTGGAAGGCCTGGCTCAAAAAATCGTCGATGGCGACGTTCCTCATAAATTGCA
AGGAAAAGAAGTCATCCGCCTAGATGTCGTGAGCCTCGTTCAGGGCACAGGCATTCGTGGTCAATTCGAAGAACGCATGC
AAAAATTAATGGATGAAATTCGTCAACGCGAAGATGTTATTCTGTTCATCGACGAAATCCATGAAATTGTTGGCGCAGGA
TCAGCTGGTGAGGGCAATATGGATGCTGGAAATATCCTTAAACCAGCCTTAGCGCGCGGAGAACTCCAATTAGTTGGGGC
TACTACCCTCAATGAATACCGTATCATTGAAAAAGATGCGGCCTTGGAACGTCGGATGCAGCCCGTTAAGGTCGATGAAC
CAACGGTTGAAGAAACCATCACCATCCTCAAGGGCATCCAGAAAAAATACGAAGACTACCACCACGTCCACTATACAGAC
GGGGCCATCGAAGCGGCAGCTATTCTTTCAAACCGCTACATCCAAGATCGCTTCCTGCCAGACAAGGCCATTGATTTGTT
GGATGAAGCGGGGTCTAAGATGAACCTGACCCTAAACTTTGTGGATCCAAAAGTGATCGACCAGCGCTTGATTGAAGCAG
AAAACCTCAAAGCCCAAGCGACGCGCGAAGAAGATTTTGAAAAAGCAGCCTACTTCCGCGACCAAATCGCGAAATACAAG
GAAATGCAGGGTCAACATGTCACCGATCAGGAAACTCCTGTCATCAGTGAAAAAACGATTGAACACATCGTTGAACAAAA
GACCAATATTCCTGTTGGTGATTTGAAAGAAAAAGAACAGTCTCAATTGATCAATCTGGCTTCTGATTTGAAAGCTCATG
TGATCGGTCAAGATGATGCAGTAGATAAAATCGCGAAAGCCATTCGACGCAATCGTGTCGGCTTAGGATCGCCTAACCGT
CCAATCGGAAGCTTCCTCTTTGTCGGACCAACTGGTGTCGGAAAGACCGAGTTGTCTAAACAATTAGCGATCGAGCTCTT
TGGCTCTGCAGACAATATGATCCGCTTTGATATGAGCGAATACATGGAAAAACATAGCGTAGCGAAACTAGTCGGAGCTC
CTCCGGGCTATGTTGGCTACGATGAAGCCGGACAACTAACTGAAAAGGTCCGTCGCAATCCATACTCCCTCGTGTTGTTG
GATGAAGTGGAAAAGGCCCATCCAGATGTCATGCACATGTTCTTGCAAGTCTTGGATGATGGCCGTTTGACAGATGGTCA
AGGTCGTACCGTCAGCTTTAAAGATACCATTATCATCATGACCTCTAATGCTGGAACCGGCAAAGCTGAGGCCAATGTTG
GTTTTGGAGCTGCTCGCGAAGGTCGAACCAACTCTGTACTGGGAGAACTCGGTAACTTCTTTAGCCCTGAATTCATGAAC
CGCTTTGATGGCATCATTGAATTCCAACCTCTATCAAAAGAAAACCTTCTCCAAATCGTTACCCTCATGCTGGATGAAGT
CAATCAACGTCTCGCACAAAATGAGATTCATCTGGATGTGACAGAGAAGGTCAAAGAAAAATTGGTCGATCTGGGATACG
ATCCAAAAATGGGGGCCCGCCCACTCCGTCGTACCATCCAAGACCATATCGAAGATGCCATTACCGATTATTACCTGGAA
CATCCAAGTGAGAAACAACTCAAAGCAGTCATGACCAGCAATGGGAATATTAGTATCAAAGCTGTTCACAAGACGGCTGA
AAAGAAGTCAGAAGCATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-726)

• AAA lid domain (AAA_lid_9) (295-392)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	87.101	100	0.871
clpE	Streptococcus pneumoniae D39	87.101	100	0.871
clpE	Streptococcus pneumoniae R6	87.101	100	0.871
clpE	Streptococcus pneumoniae TIGR4	87.101	100	0.871
clpE	Streptococcus mutans UA159	83.979	99.601	0.836
clpC	Lactococcus lactis subsp. cremoris KW2	75.561	100	0.761
clpC	Bacillus subtilis subsp. subtilis str. 168	50.425	93.883	0.473
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.699	86.702	0.414
clpC	Streptococcus pneumoniae Rx1	47.84	83.112	0.398
clpC	Streptococcus pneumoniae D39	47.84	83.112	0.398
clpC	Streptococcus pneumoniae TIGR4	47.68	83.112	0.396
clpC	Streptococcus mutans UA159	46.88	83.112	0.39
clpC	Streptococcus thermophilus LMD-9	47.03	82.846	0.39
clpC	Streptococcus thermophilus LMG 18311	46.785	82.713	0.387