Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   F5989_RS10010 Genome accession   NZ_CP044221
Coordinates   1991377..1992270 (-) Length   297 a.a.
NCBI ID   WP_002270555.1    Uniprot ID   A0A0H5BB73
Organism   Streptococcus mutans strain NCH105     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1986377..1997270
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F5989_RS09985 (F5989_10170) cas1 1987506..1988372 (+) 867 WP_002277049.1 type II CRISPR-associated endonuclease Cas1 -
  F5989_RS09990 (F5989_10175) cas2 1988369..1988713 (+) 345 WP_002263547.1 CRISPR-associated endonuclease Cas2 -
  F5989_RS09995 (F5989_10180) csn2 1988703..1989365 (+) 663 WP_002289642.1 type II-A CRISPR-associated protein Csn2 -
  F5989_RS10000 (F5989_10185) - 1989462..1989653 (+) 192 WP_002289644.1 type II toxin-antitoxin system HicA family toxin -
  F5989_RS10005 (F5989_10190) - 1989671..1990048 (+) 378 WP_002265422.1 type II toxin-antitoxin system HicB family antitoxin -
  F5989_RS10010 (F5989_10195) irvR 1991377..1992270 (-) 894 WP_002270555.1 XRE family transcriptional regulator Regulator
  F5989_RS10015 (F5989_10200) - 1992594..1992878 (+) 285 WP_002262720.1 helix-turn-helix transcriptional regulator -
  F5989_RS10020 (F5989_10205) gbpC 1993041..1994792 (+) 1752 WP_002289758.1 glucan-binding protein GbpC -
  F5989_RS10310 (F5989_10210) - 1994922..1995152 (+) 231 WP_024784882.1 hypothetical protein -
  F5989_RS10360 (F5989_10215) - 1995187..1995315 (+) 129 WP_002262718.1 hypothetical protein -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33658.57 Da        Isoelectric Point: 7.6072

>NTDB_id=388882 F5989_RS10010 WP_002270555.1 1991377..1992270(-) (irvR) [Streptococcus mutans strain NCH105]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQKETVTIAADDKTSEDTITSKSHHAEYQKIVDSYIAKELKDQTI
IHWDNVIKAKDLYQTLGRQHENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALTVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=388882 F5989_RS10010 WP_002270555.1 1991377..1992270(-) (irvR) [Streptococcus mutans strain NCH105]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCGATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCTACTATCCTTAACATTCCTACAAGTAGTCTTAATGAATATGTTAAAGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTCTCCAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTATCAACAATCAAAAGAACAAAAAGAAACTGTGACCATAGCTGCTGACGATAAAACATCTGAAGATACGA
TTACCAGCAAATCTCATCATGCAGAATATCAAAAGATTGTCGACTCTTATATCGCCAAAGAGTTAAAAGATCAAACCATT
ATTCATTGGGACAATGTGATAAAAGCTAAAGATCTGTATCAAACCTTAGGACGTCAACACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTACTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Peptidase S24-like (Peptidase_S24)

(184-296)

Helix-turn-helix (HTH_3)

(22-70)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H5BB73

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

92.929

100

0.929

Multiple sequence alignment