Detailed information NTG0388824

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: F5989_RS03760
• Genome accession: NZ_CP044221
• Coordinates: 780241..782502 (+)
• Length: 753 a.a.
• NCBI ID: WP_002267212.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain NCH105
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 775241..787502

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F5989_RS03735 (F5989_03790)	-	776394..776870 (-)	477	WP_002263564.1	ferrous iron transport protein A	-
F5989_RS03740 (F5989_03795)	-	777063..777797 (-)	735	WP_002264702.1	amino acid ABC transporter ATP-binding protein	-
F5989_RS03745 (F5989_03800)	-	777797..778483 (-)	687	WP_002263566.1	amino acid ABC transporter permease	-
F5989_RS03750 (F5989_03805)	-	778697..778927 (-)	231	WP_002263567.1	YkuJ family protein	-
F5989_RS03755 (F5989_03810)	argF	779004..779984 (-)	981	WP_002267213.1	ornithine carbamoyltransferase	-
F5989_RS03760 (F5989_03815)	clpE	780241..782502 (+)	2262	WP_002267212.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
F5989_RS03765 (F5989_03820)	-	782613..783068 (+)	456	WP_002267211.1	NUDIX hydrolase	-
F5989_RS03770 (F5989_03825)	-	783135..783437 (+)	303	WP_002263571.1	DUF1827 family protein	-
F5989_RS03775 (F5989_03830)	ileS	784206..786998 (-)	2793	WP_002271247.1	isoleucine--tRNA ligase	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83745.87 Da
• Isoelectric Point: 5.0580

>NTDB_id=388824 F5989_RS03760 WP_002267212.1 780241..782502(+) (clpE) [Streptococcus mutans strain NCH105]
MLCQNCKLNEATIHLYANVNGQQKQIDLCQNCYQIMKTDPENGPLNHLSQQNSSPTNPFFDDFFGDLNNFRAFNNQDLPN
TPPTQAGGGNGNGGNNRRPGGPQQQASQKPNGLLEEFGINLTDIARKGEIDPVIGRDEEITRVIEILNRRTKNNPVLIGE
PGVGKTAVVEGLAQKIVDGDVPQKLHGKNVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGS
AGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVAETITILKGIQPKYEDYHHVKYTDE
AIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDHRLIEAENLKAQATRDEDYEKAAYFRDQIAKYKE
MQSAKLDKENTPVITEKNIEVIVEQKTNIPVGELKEKEQSQLIHLADDLKTRVIGQDAAVDKIAKAIRRNRVGLGTPNRP
IGSFLFVGPTGVGKTELSKQLAIELFGSEDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLD
EVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEANVGFGASREGRTNSVLGELGNFFSPEFMNR
FDGIIEFQALSKDNLLQIVSLMLDDVNQRLAVNAIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDFYLEH
PDQKELKAIMTSNGKIVIRASNKVETVTKATSD

Nucleotide

• Length: 2262 bp

>NTDB_id=388824 F5989_RS03760 WP_002267212.1 780241..782502(+) (clpE) [Streptococcus mutans strain NCH105]
ATGCTCTGTCAAAATTGTAAATTAAATGAAGCGACTATTCATCTATATGCTAATGTTAATGGTCAGCAAAAGCAGATTGA
CCTTTGTCAAAATTGTTATCAAATTATGAAAACGGATCCTGAAAATGGACCTTTAAATCATCTTTCGCAACAAAATTCGT
CACCCACCAATCCTTTCTTTGATGATTTCTTTGGCGATTTGAATAATTTTCGTGCCTTTAATAATCAAGATCTGCCAAAC
ACACCGCCAACACAAGCTGGCGGCGGCAATGGCAACGGAGGCAATAATCGCCGTCCCGGCGGACCTCAGCAACAGGCCTC
CCAAAAGCCAAATGGGTTGCTTGAAGAGTTTGGTATTAATTTAACAGATATTGCGCGCAAGGGTGAAATTGATCCTGTTA
TTGGCCGTGATGAAGAAATCACAAGGGTTATCGAAATTCTCAACCGTCGCACAAAGAATAATCCTGTTCTTATTGGAGAA
CCGGGTGTCGGTAAAACTGCTGTTGTCGAAGGACTAGCGCAAAAAATTGTTGATGGTGATGTTCCACAAAAATTACATGG
AAAAAATGTCATTCGTCTGGACGTCGTCAGCCTTGTTCAAGGTACTGGTATTCGAGGCCAATTTGAAGAACGGATGCAAA
AATTAATGGAAGAAATCCGTCAACGTCAAGATGTTATTCTTTTCATTGATGAAATTCATGAAATTGTTGGTGCTGGTTCT
GCTGGCGATGGCAATATGGATGCCGGAAATATTTTAAAACCCGCTTTGGCACGCGGTGAGCTTCAACTTGTTGGTGCTAC
AACACTCAATGAATATCGGATTATTGAAAAAGATGCCGCTTTGGAACGTCGAATGCAACCCGTAAAAGTTGATGAACCTA
GTGTTGCAGAAACCATAACGATTCTTAAAGGTATTCAGCCCAAATATGAAGATTACCATCATGTAAAGTATACAGATGAA
GCGATTGAAGCTGCTGCAAATCTTTCAAATCGTTACATTCAGGATCGTTTTTTACCTGATAAGGCTATTGATCTTCTAGA
TGAAGCTGGCTCTAAAATGAATTTAACACTTAACTTTGTAGATCCTAAAGAAATTGATCACCGCTTGATTGAAGCCGAAA
ATCTAAAAGCTCAAGCAACCCGTGATGAAGATTATGAAAAAGCAGCTTACTTCCGTGATCAAATTGCCAAATACAAGGAA
ATGCAATCCGCTAAACTTGATAAGGAGAATACTCCTGTTATTACCGAAAAAAATATTGAAGTAATTGTCGAGCAAAAGAC
CAATATTCCTGTTGGTGAATTAAAAGAAAAGGAACAATCACAATTAATTCATCTCGCTGACGATCTTAAAACGCGTGTTA
TTGGACAGGATGCCGCTGTTGATAAAATTGCTAAAGCTATTCGCCGCAATCGTGTTGGACTAGGCACTCCAAATCGGCCA
ATTGGTTCTTTCCTTTTTGTCGGCCCTACTGGTGTTGGTAAAACGGAACTCTCTAAACAATTAGCTATTGAGCTTTTTGG
TTCTGAAGATAGTATGATTCGTTTCGATATGAGTGAATACATGGAAAAACATGCTGTGGCTAAACTTGTTGGTGCACCTC
CGGGATATGTCGGTTATGAAGAAGCTGGTCAGTTAACCGAAAAAGTTCGTCGCAACCCTTATTCATTGATCTTACTCGAT
GAAGTTGAAAAAGCTCACCCAGATGTCATGCATATGTTCTTACAAGTGCTTGATGATGGTCGTCTAACGGATGGGCAAGG
ACGCACTGTCAGCTTTAAGGATACTATTATTATCATGACCTCAAATGCTGGTACAGGGAAATCTGAAGCTAATGTTGGTT
TTGGTGCCAGTCGAGAAGGCCGTACTAATTCTGTTCTAGGCGAATTGGGTAACTTCTTTAGCCCTGAATTTATGAACCGT
TTTGATGGTATCATCGAATTTCAGGCTTTAAGCAAGGATAACCTTCTTCAAATTGTTTCTCTCATGCTGGATGACGTTAA
TCAACGTTTAGCTGTTAATGCTATTCACCTTGATGTAACTGATAAAGTTAAAGAAAAATTGGTTGATCTCGGTTATGATC
CTAAAATGGGAGCAAGACCGCTGCGTCGTACTATCCAAGAACATATTGAAGATGCTATTACGGATTTCTACTTAGAGCAT
CCTGATCAAAAAGAACTAAAAGCTATTATGACAAGCAATGGCAAAATTGTTATCAGGGCTTCTAACAAAGTCGAAACGGT
TACCAAAGCAACTTCAGATTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (479-642)

• AAA lid domain (AAA_lid_9) (294-391)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (650-721)

• ATPase family associated with various cellular activities (AAA) (AAA) (156-275)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	99.469	100	0.995
clpE	Streptococcus pneumoniae Rx1	82.62	99.336	0.821
clpE	Streptococcus pneumoniae D39	82.62	99.336	0.821
clpE	Streptococcus pneumoniae R6	82.62	99.336	0.821
clpE	Streptococcus pneumoniae TIGR4	82.62	99.336	0.821
clpC	Lactococcus lactis subsp. cremoris KW2	76.159	100	0.764
clpC	Bacillus subtilis subsp. subtilis str. 168	53.159	86.189	0.458
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48	86.321	0.414
clpC	Streptococcus pneumoniae Rx1	49.355	82.337	0.406
clpC	Streptococcus pneumoniae D39	49.355	82.337	0.406
clpC	Streptococcus pneumoniae TIGR4	49.194	82.337	0.405
clpC	Streptococcus thermophilus LMD-9	47.764	83.134	0.397
clpC	Streptococcus thermophilus LMG 18311	47.444	83.134	0.394
clpC	Streptococcus mutans UA159	47.011	82.205	0.386