Detailed information NTG0388756

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: F6X00_RS06735
• Genome accession: NZ_CP044206
• Coordinates: 1420726..1421595 (-)
• Length: 289 a.a.
• NCBI ID: WP_043877313.1
• Uniprot ID: B7U4T2
• Organism: Vibrio vulnificus strain Vv180806
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1415726..1426595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F6X00_RS06700 (F6X00_06825)	rpsP	1416885..1417133 (+)	249	WP_011079541.1	30S ribosomal protein S16	-
F6X00_RS06705 (F6X00_06830)	rimM	1417149..1417697 (+)	549	WP_011079542.1	ribosome maturation factor RimM	-
F6X00_RS06710 (F6X00_06835)	trmD	1417725..1418474 (+)	750	WP_011079543.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
F6X00_RS06715 (F6X00_06840)	rplS	1418516..1418869 (+)	354	WP_011079544.1	50S ribosomal protein L19	-
F6X00_RS06720 (F6X00_06845)	yacG	1419086..1419280 (-)	195	WP_026060801.1	DNA gyrase inhibitor YacG	-
F6X00_RS06725 (F6X00_06850)	zapD	1419343..1420083 (-)	741	WP_011079546.1	cell division protein ZapD	-
F6X00_RS06730 (F6X00_06855)	coaE	1420116..1420724 (-)	609	WP_039554617.1	dephospho-CoA kinase	-
F6X00_RS06735 (F6X00_06860)	pilD	1420726..1421595 (-)	870	WP_043877313.1	A24 family peptidase	Machinery gene
F6X00_RS06740 (F6X00_06865)	pilC	1421689..1422915 (-)	1227	WP_182290672.1	type II secretion system F family protein	Machinery gene
F6X00_RS06745 (F6X00_06870)	pilB	1422964..1424652 (-)	1689	WP_182290674.1	type IV-A pilus assembly ATPase PilB	Machinery gene
F6X00_RS06750 (F6X00_06875)	-	1424662..1425093 (-)	432	WP_130341685.1	pilin	-
F6X00_RS06755 (F6X00_06880)	nadC	1425313..1426200 (-)	888	WP_182290675.1	carboxylating nicotinate-nucleotide diphosphorylase	-

Sequence

Protein

• Length: 289 a.a.
• Molecular weight: 32231.26 Da
• Isoelectric Point: 6.4630

>NTDB_id=388756 F6X00_RS06735 WP_043877313.1 1420726..1421595(-) (pilD) [Vibrio vulnificus strain Vv180806]
MDALQYYPWLYIGLASLFGLLVGSFLNVVIYRLPKIMELEWRQECAESFPEYNITPPTETLTLSTPRSSCPSCHTPIRVR
DNIPVFSWLALRGKCHHCQTKISARYPFVEALSAFLCGLVAWKFGYAPITVALIGFTLVLIAATFIDLDTMLLPDQLTLP
LTWAGIALALLEISPVSLQDSVIGAMAGYLCLWSVYHLFRLLTGKEGMGYGDFKLLAALGAWLGWQYLPMIILLSSVVGL
IFGLIQLRLQKQGIEMAFPFGPYLAIAGWVALMWGDSLMSWYLNYLIGA

Nucleotide

• Length: 870 bp

>NTDB_id=388756 F6X00_RS06735 WP_043877313.1 1420726..1421595(-) (pilD) [Vibrio vulnificus strain Vv180806]
ATGGACGCGTTACAATACTACCCTTGGCTTTATATTGGTTTAGCTTCCCTGTTTGGCTTACTGGTAGGCAGCTTTCTTAA
CGTCGTCATCTACCGTCTACCGAAAATAATGGAACTGGAATGGCGCCAAGAGTGTGCTGAGTCTTTTCCTGAATACAACA
TCACACCACCGACAGAAACCCTAACATTAAGCACGCCGCGCTCAAGTTGTCCTTCGTGCCATACCCCAATACGAGTTCGA
GATAATATTCCTGTCTTTAGTTGGTTAGCACTAAGAGGAAAATGTCACCATTGCCAGACGAAAATCAGTGCTCGCTATCC
TTTTGTTGAAGCACTGAGCGCCTTTTTGTGCGGCCTAGTCGCTTGGAAGTTCGGTTATGCACCGATTACCGTAGCACTGA
TTGGTTTTACTTTGGTGTTGATCGCCGCCACCTTCATCGACTTAGATACCATGCTACTGCCTGATCAGCTGACACTGCCG
CTGACGTGGGCAGGCATCGCGCTAGCGTTACTAGAGATAAGCCCAGTATCTCTGCAAGATTCAGTGATCGGTGCGATGGC
AGGCTATCTCTGCCTTTGGAGCGTTTATCACCTTTTCCGATTGCTGACAGGGAAAGAAGGCATGGGTTACGGAGACTTTA
AATTGCTTGCGGCACTTGGAGCTTGGCTCGGCTGGCAATATCTACCGATGATCATCTTACTCTCTTCGGTTGTCGGGCTG
ATCTTTGGTCTCATTCAACTCAGATTGCAAAAGCAAGGCATTGAGATGGCTTTTCCATTTGGGCCTTATCTGGCCATTGC
TGGTTGGGTCGCCTTAATGTGGGGAGATAGCTTGATGTCTTGGTATCTCAACTATCTTATAGGGGCGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (137-244)

3D structure

• AlphaFold DB: B7U4T2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio campbellii strain DS40M4	77.431	99.654	0.772
pilD	Vibrio cholerae strain A1552	71.875	99.654	0.716
pilD	Acinetobacter nosocomialis M2	54.348	95.502	0.519
pilD	Acinetobacter baumannii D1279779	54.348	95.502	0.519
pilD	Neisseria gonorrhoeae MS11	48	95.156	0.457