Detailed information    

insolico Bioinformatically predicted

Overview

Name   waaF   Type   Regulator
Locus tag   F4V26_RS03580 Genome accession   NZ_CP044169
Coordinates   688957..689916 (-) Length   319 a.a.
NCBI ID   WP_002876195.1    Uniprot ID   -
Organism   Campylobacter jejuni strain AR-0414     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 686088..723024 688957..689916 within 0


Gene organization within MGE regions


Location: 686088..723024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F4V26_RS03565 rfaD 686088..687041 (+) 954 WP_002886910.1 ADP-glyceromanno-heptose 6-epimerase -
  F4V26_RS03570 rfaE1 687034..688419 (+) 1386 WP_002910336.1 D-glycero-beta-D-manno-heptose-7-phosphate kinase -
  F4V26_RS03575 gmhA 688416..688976 (+) 561 WP_002876196.1 D-sedoheptulose 7-phosphate isomerase -
  F4V26_RS03580 waaF 688957..689916 (-) 960 WP_002876195.1 lipopolysaccharide heptosyltransferase II Regulator
  F4V26_RS03585 - 689975..690793 (+) 819 WP_002876193.1 glycosyltransferase family 2 protein -
  F4V26_RS03590 wlaTC 690796..691755 (-) 960 WP_002876191.1 class E lipooligosaccharide biosynthesis protein WlaTC -
  F4V26_RS03595 wlaTB 691752..692708 (-) 957 WP_002860237.1 class E lipooligosaccharide biosynthesis protein WlaTB -
  F4V26_RS03600 - 692701..693474 (-) 774 WP_002866160.1 glycosyltransferase family 25 protein -
  F4V26_RS03605 - 693545..694567 (+) 1023 WP_002876190.1 hypothetical protein -
  F4V26_RS03610 - 694564..695817 (+) 1254 WP_002876189.1 DUF2972 domain-containing protein -
  F4V26_RS03615 wlaRG 695849..696934 (-) 1086 WP_002876187.1 class E lipooligosaccharide biosynthesis aminotransferase WlaRG -
  F4V26_RS03620 - 696931..698007 (-) 1077 WP_002876186.1 glycosyltransferase family A protein -
  F4V26_RS03630 - 698304..698831 (-) 528 WP_044278676.1 GNAT family N-acetyltransferase -
  F4V26_RS03635 - 698828..699295 (-) 468 WP_002869597.1 acyltransferase -
  F4V26_RS03640 wlaRB 699285..699689 (-) 405 WP_002860228.1 class E lipooligosaccharide biosynthesis 3,4-ketoisomerase WlaRB -
  F4V26_RS03645 wlaRA 699697..700134 (-) 438 WP_002891875.1 class E lipooligosaccharide biosynthesis 3,4-ketoisomerase WlaRA -
  F4V26_RS03650 rfbB 700137..701168 (-) 1032 WP_002860226.1 dTDP-glucose 4,6-dehydratase -
  F4V26_RS03655 rfbA 701168..702046 (-) 879 WP_002869595.1 glucose-1-phosphate thymidylyltransferase RfbA -
  F4V26_RS03660 - 702057..702758 (-) 702 WP_002876132.1 glycosyltransferase family 2 protein -
  F4V26_RS03665 htrB 702755..703633 (-) 879 WP_002876133.1 lipid A biosynthesis lauroyl acyltransferase HtrB -
  F4V26_RS03670 waaC 703623..704651 (-) 1029 WP_002876134.1 lipopolysaccharide heptosyltransferase I -
  F4V26_RS03675 - 704718..705512 (+) 795 WP_002860221.1 3'-5' exonuclease -
  F4V26_RS03680 galE 705571..706557 (+) 987 WP_002869588.1 UDP-glucose 4-epimerase GalE -
  F4V26_RS03685 pglK 706551..708245 (+) 1695 WP_002869587.1 ABC-type lipopolysaccharide transporter PglK -
  F4V26_RS03690 pglH 708242..709321 (+) 1080 WP_079264556.1 GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)- diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase -
  F4V26_RS03695 pglI 709314..710243 (+) 930 WP_002867212.1 GalNAc(5)-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase -
  F4V26_RS03700 pglJ 710231..711328 (+) 1098 WP_002870121.1 N-acetylgalactosamine-N, N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase -
  F4V26_RS03705 pglB 711332..713473 (+) 2142 WP_150969759.1 undecaprenyl-diphosphooligosaccharide--protein glycotransferase -
  F4V26_RS03710 pglA 713483..714613 (+) 1131 WP_002870124.1 N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase -
  F4V26_RS03715 pglC 714606..715208 (+) 603 WP_002852766.1 undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase -
  F4V26_RS03720 pglD 715195..715785 (+) 591 WP_002870125.1 UDP-N-acetylbacillosamine N-acetyltransferase -
  F4V26_RS03725 pglE 715883..717043 (+) 1161 WP_002870126.1 UDP-N-acetylbacillosamine transaminase -
  F4V26_RS03730 pglF 717045..718817 (+) 1773 WP_002870127.1 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) -
  F4V26_RS03735 pglG 718817..719710 (+) 894 WP_002856519.1 PDC sensor domain-containing protein -
  F4V26_RS03740 cheY 719823..720215 (+) 393 WP_002866134.1 chemotaxis response regulator CheY -
  F4V26_RS03745 prmA 720238..721083 (+) 846 WP_002856135.1 50S ribosomal protein L11 methyltransferase -
  F4V26_RS03750 ftsH 721087..723024 (+) 1938 WP_002856296.1 ATP-dependent zinc metalloprotease FtsH -

Sequence

Protein


Download         Length: 319 a.a.        Molecular weight: 36607.08 Da        Isoelectric Point: 10.2870

>NTDB_id=388496 F4V26_RS03580 WP_002876195.1 688957..689916(-) (waaF) [Campylobacter jejuni strain AR-0414]
MKIFIHLPTWLGDAVMASPALYAIKEHFKNAQFILYGSLVSTALFKEFPNSKIIIENKQSRYKQALSLRKELGKIDLSFA
FRSAFSSKIILHILKTKQRYFFDKNKHKEEHQVLKYLYFIENSLSIKAHSKDLKLPFKLKLQDPLVLKNGKKILGLNPGA
SFGSAKRWDASYFAKVALNFSQSHEILIFGAGKSEQELCNEIYQILKEQNIKVKNLCNKTTIKTLCQNIAFCDLFITNDS
GPMHISAVYKVKTVAIFGPTKFTQTSPWQNENAILVHLDLACMPCMQKTCPLKHHKCMKDLKPQRVIEEARNLLKNSHR

Nucleotide


Download         Length: 960 bp        

>NTDB_id=388496 F4V26_RS03580 WP_002876195.1 688957..689916(-) (waaF) [Campylobacter jejuni strain AR-0414]
ATGAAAATTTTTATACATCTTCCCACTTGGCTGGGCGATGCAGTGATGGCTTCACCTGCTTTATACGCTATAAAAGAACA
TTTTAAAAATGCCCAATTTATCCTTTATGGCTCTTTAGTTTCCACAGCACTTTTTAAAGAATTTCCTAATTCTAAAATCA
TCATAGAAAATAAACAATCTCGCTATAAACAAGCCCTATCTTTACGCAAAGAACTTGGTAAGATCGATCTTAGCTTTGCT
TTTAGATCTGCGTTTTCTTCTAAGATTATCTTGCATATCCTTAAAACAAAACAAAGATATTTTTTTGACAAAAACAAGCA
CAAAGAAGAACATCAAGTTTTAAAATACCTTTATTTTATAGAAAACTCACTTAGTATAAAAGCTCATTCTAAAGACTTAA
AGCTTCCCTTTAAGCTAAAACTTCAAGACCCTCTTGTCTTAAAAAATGGTAAAAAAATTCTAGGACTCAATCCTGGCGCA
AGCTTTGGAAGTGCAAAAAGATGGGATGCGAGTTATTTTGCTAAAGTGGCTTTAAATTTCAGCCAAAGTCATGAAATTTT
AATCTTTGGCGCAGGAAAATCCGAACAAGAACTTTGTAATGAAATTTATCAAATTTTAAAAGAACAAAACATAAAAGTAA
AAAATCTTTGCAACAAAACCACCATCAAAACCCTTTGTCAAAATATCGCTTTTTGCGATCTTTTCATCACAAATGACAGT
GGTCCTATGCACATAAGTGCGGTTTATAAGGTAAAAACCGTAGCTATTTTTGGCCCTACGAAATTTACTCAAACTTCACC
TTGGCAAAATGAAAACGCAATATTAGTGCATTTAGATCTAGCTTGTATGCCTTGTATGCAAAAAACCTGCCCTTTAAAAC
ACCACAAATGCATGAAAGATCTAAAGCCTCAAAGGGTTATAGAAGAGGCTAGAAATTTACTTAAAAACTCTCATCGATGA

Domains

Predicted by InterproScan.

Glycosyltransferase family 9 (heptosyltransferase) (Glyco_transf_9)

(94-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  waaF Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

94.025

99.687

0.937

Multiple sequence alignment