Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   HIR76_RS18715 Genome accession   NZ_CP051860
Coordinates   3578983..3579696 (-) Length   237 a.a.
NCBI ID   WP_003244535.1    Uniprot ID   O06978
Organism   Bacillus subtilis subsp. subtilis str. 168     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3573983..3584696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIR76_RS18695 (HIR76_08895) ghrB 3574127..3575104 (+) 978 WP_010886621.1 bifunctional glyoxylate/hydroxypyruvate reductase B -
  HIR76_RS18700 (HIR76_08890) psdB 3575142..3577082 (-) 1941 WP_003243432.1 lantibiotic ABC transporter permease PsdB -
  HIR76_RS18705 (HIR76_08885) psdA 3577057..3577836 (-) 780 WP_003228167.1 lantibiotic ABC transporter ATP-binding protein PsdA -
  HIR76_RS18710 (HIR76_08880) psdS 3577919..3578989 (-) 1071 WP_003242699.1 two-component sensor histidine kinase PsdS -
  HIR76_RS18715 (HIR76_08875) braR 3578983..3579696 (-) 714 WP_003244535.1 two-component system response regulator PsdR Regulator
  HIR76_RS18720 (HIR76_08870) yvzJ 3579843..3580052 (+) 210 WP_003243327.1 lipoprotein -
  HIR76_RS18725 (HIR76_08865) yvcN 3580088..3580852 (-) 765 WP_009968228.1 arylamine N-acetyltransferase -
  HIR76_RS18730 (HIR76_08860) crh 3580853..3581110 (-) 258 WP_003219835.1 HPr family phosphocarrier protein -
  HIR76_RS18735 (HIR76_08855) whiA 3581134..3582084 (-) 951 WP_003243775.1 DNA-binding protein WhiA -
  HIR76_RS18740 (HIR76_08850) mgfK 3582107..3583060 (-) 954 WP_003244450.1 gluconeogenesis morphogenetic factor -
  HIR76_RS18745 (HIR76_08845) rapZ 3583062..3583949 (-) 888 WP_003243903.1 RNase adapter RapZ -
  HIR76_RS18750 (HIR76_08840) rppI 3583974..3584450 (-) 477 WP_010886622.1 8-oxo-dGTP diphosphatase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27514.39 Da        Isoelectric Point: 4.6062

>NTDB_id=388353 HIR76_RS18715 WP_003244535.1 3578983..3579696(-) (braR) [Bacillus subtilis subsp. subtilis str. 168]
MYRILLVEDDERIASLLGGHLQKYGYEVKIAEQLNDIKLEFAEMKPDLVLLDINLPFFDGFYWCRQIRTISNAPIIFISA
RTDELNQVMAIENGGDDYITKPFHLEVVMAKIKSVLRRTYGEYSPSLPQESRIVELGGLTIYPDQNEAEWNSVRILFSQK
EFQLLSIFVREHKKIVSRDELLEALWDDVDFVDDNTLTVNVNRLRRKLENAGLTDCISTIRGQGYQFQVNRKDEAEC

Nucleotide


Download         Length: 714 bp        

>NTDB_id=388353 HIR76_RS18715 WP_003244535.1 3578983..3579696(-) (braR) [Bacillus subtilis subsp. subtilis str. 168]
GTGTATCGGATTTTGCTTGTGGAAGATGATGAGCGGATTGCTTCTTTGCTGGGCGGTCATCTTCAAAAATACGGATATGA
AGTGAAAATTGCTGAACAGCTGAATGATATAAAATTGGAATTTGCAGAAATGAAGCCTGATCTTGTGCTGCTTGATATCA
ACCTGCCTTTTTTTGACGGGTTTTATTGGTGCAGGCAAATCCGTACCATTTCCAATGCGCCGATTATCTTTATATCGGCA
CGGACCGATGAGCTGAATCAGGTAATGGCGATTGAAAATGGCGGCGATGATTATATCACAAAGCCGTTCCATCTAGAGGT
AGTGATGGCCAAAATCAAAAGCGTCCTGCGCCGCACATATGGTGAATATTCGCCCTCTTTGCCGCAGGAATCTAGAATAG
TGGAGCTTGGCGGGCTGACGATTTATCCTGATCAGAATGAGGCCGAATGGAACAGCGTCCGGATTTTGTTTTCCCAAAAA
GAATTCCAGCTTCTCTCGATTTTTGTGAGGGAGCATAAAAAAATTGTCTCTCGTGATGAACTATTGGAGGCGTTATGGGA
TGACGTTGATTTTGTCGATGACAATACGTTAACGGTCAATGTCAATCGGCTGCGGAGAAAACTGGAGAATGCAGGACTGA
CAGATTGCATTTCCACAATCAGAGGACAAGGTTATCAATTTCAAGTCAATCGGAAGGATGAAGCGGAATGTTAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O06978

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

45.536

94.515

0.43