Detailed information NTG0387904

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FOB68_RS01660
• Genome accession: NZ_CP044106
• Coordinates: 288854..289897 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_660
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 283854..294897

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB68_RS01625 (FOB68_01630)	-	284280..284390 (+)	111	WP_001790257.1	hypothetical protein	-
FOB68_RS01630 (FOB68_01635)	-	284419..284832 (+)	414	WP_025174552.1	hypothetical protein	-
FOB68_RS01640 (FOB68_01645)	-	285265..286251 (-)	987	WP_000999708.1	FUSC family protein	-
FOB68_RS01645 (FOB68_01650)	map	286780..287538 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FOB68_RS01650 (FOB68_01655)	-	287755..288141 (+)	387	WP_001110179.1	hypothetical protein	-
FOB68_RS01655 (FOB68_01660)	liaF	288156..288857 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FOB68_RS01660 (FOB68_01665)	vraS	288854..289897 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FOB68_RS01665 (FOB68_01670)	vraR	289887..290516 (+)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
FOB68_RS01670 (FOB68_01675)	-	290629..291846 (-)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
FOB68_RS01675 (FOB68_01680)	-	292124..292399 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
FOB68_RS01680 (FOB68_01685)	-	292406..292870 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FOB68_RS01685 (FOB68_01690)	-	293017..293217 (+)	201	WP_000180460.1	DUF1128 family protein	-
FOB68_RS01690 (FOB68_01695)	-	293220..294476 (+)	1257	WP_078065149.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=387904 FOB68_RS01660 WP_001017131.1 288854..289897(+) (vraS) [Staphylococcus aureus strain FDAARGOS_660]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=387904 FOB68_RS01660 WP_001017131.1 288854..289897(+) (vraS) [Staphylococcus aureus strain FDAARGOS_660]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1