Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   FOB62_RS00575 Genome accession   NZ_CP044102
Coordinates   108334..110433 (+) Length   699 a.a.
NCBI ID   WP_014612218.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_654     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 103334..115433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB62_RS00545 (FOB62_00545) - 104205..105310 (+) 1106 WP_139818575.1 IS3 family transposase -
  FOB62_RS00550 (FOB62_00550) - 105356..105622 (+) 267 Protein_105 integrase core domain-containing protein -
  FOB62_RS00555 (FOB62_00555) rplL 106000..106365 (-) 366 WP_003043797.1 50S ribosomal protein L7/L12 -
  FOB62_RS00560 (FOB62_00560) rplJ 106430..106930 (-) 501 WP_003050354.1 50S ribosomal protein L10 -
  FOB62_RS00565 (FOB62_00565) - 107259..107435 (-) 177 Protein_108 IS30 family transposase -
  FOB62_RS00570 (FOB62_00570) - 107429..107836 (+) 408 Protein_109 IS30 family transposase -
  FOB62_RS00575 (FOB62_00575) clpC 108334..110433 (+) 2100 WP_014612218.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FOB62_RS00580 (FOB62_00580) - 110444..111232 (-) 789 WP_138128043.1 hypothetical protein -
  FOB62_RS00585 (FOB62_00585) yihA 111376..111975 (-) 600 WP_003061604.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  FOB62_RS00590 (FOB62_00590) clpX 111985..113214 (-) 1230 WP_014612216.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  FOB62_RS00595 (FOB62_00595) - 113328..113498 (-) 171 WP_003054200.1 hypothetical protein -
  FOB62_RS00600 (FOB62_00600) - 113518..114015 (-) 498 WP_003054187.1 dihydrofolate reductase -
  FOB62_RS00605 (FOB62_00605) - 114096..114935 (-) 840 WP_003054196.1 thymidylate synthase -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77471.11 Da        Isoelectric Point: 4.8291

>NTDB_id=387842 FOB62_RS00575 WP_014612218.1 108334..110433(+) (clpC) [Streptococcus dysgalactiae strain FDAARGOS_654]
MTNYYDKDTFGNMDDIFNQLMGNMGGYRSENRRYLVNGREMTPEEFQAYRQTGRLSDKGSEQPTSQGHQTKKDGILAKLG
TNLTEEARQGKLDPVIGRNHEIQDTAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENIQNMIQEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADMLKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHNVILPDAVLKAAIDYSIQYIPQRSLPDKAIDLVDMTAAHLAA
QHPVTDLKSLEAEMTTQKNIQEEAVAKEDFERALTAKTRIEELQKQMDNHSEDQKVTATVNDIAESVERLTGVPVSNMGA
SDLERLKEISNRLKEHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKEAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGHQEDENTDQPTIMDRIAPYFRPEFLNRFNGVIEFNHLQKEDLEEIVDLMLAEVNQTIAKKGISLAISDD
AKAHLIELGYDHAMGVRPLRRVIEQEIRDRITDFYLDHPEVKNLQASLEQGQLVIHDKN

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=387842 FOB62_RS00575 WP_014612218.1 108334..110433(+) (clpC) [Streptococcus dysgalactiae strain FDAARGOS_654]
ATGACAAATTATTATGACAAAGATACTTTTGGAAACATGGATGATATCTTTAATCAACTAATGGGCAATATGGGTGGCTA
TCGCAGTGAAAATCGACGCTATTTAGTGAACGGACGCGAAATGACACCTGAAGAATTCCAGGCATATCGTCAAACTGGAC
GTCTGAGCGATAAAGGTAGTGAACAACCTACATCCCAAGGTCATCAGACCAAAAAGGATGGGATTTTAGCTAAACTTGGC
ACCAACTTAACGGAAGAAGCAAGACAAGGAAAACTTGATCCTGTTATTGGTCGCAATCACGAAATTCAAGACACTGCGGA
AATTTTAGCTCGCCGAACAAAGAATAATCCTGTTCTAGTCGGAGATGCTGGTGTTGGTAAAACAGCTGTGGTTGAAGGGC
TAGCTCAAGCTATTGTGAATGGTGACGTCCCTGCTGCTATCAAAAATAAAGAAATCATTTCCATTGATATTTCTGGCCTT
GAAGCAGGCACTCAGTACCGTGGCTCCTTTGAAGAAAATATCCAAAACATGATTCAAGAGGTTAAAGAAGCTGGGAATAT
TATTCTTTTCTTTGATGAAATTCATCAAATCCTTGGTGCAGGTTCTACTGGTGGTGACTCTGGGTCTAAAGGATTAGCTG
ATATGCTAAAACCTGCTCTTTCCCGTGGTGAATTGACACTGATTGGCGCCACAACTCAAGATGAATACCGCAATACCATT
TTAAAAAATGCTGCGCTTGCTCGTCGTTTTAATGAGGTTAAGGTAAATGCACCGTCTGCTGAGGACACCTTCCATATTTT
AATGGGAATCCGAAATCTTTACGAACAACACCATAATGTTATCCTTCCGGATGCTGTTCTTAAAGCTGCGATTGACTATT
CTATTCAGTACATTCCTCAACGTAGTTTACCAGATAAAGCGATTGACTTAGTAGATATGACTGCTGCGCATTTAGCCGCT
CAGCATCCTGTGACTGACCTCAAGTCTCTAGAAGCTGAAATGACCACTCAAAAGAATATCCAAGAAGAGGCTGTGGCTAA
GGAAGATTTTGAGAGAGCTTTAACCGCTAAAACACGAATTGAAGAATTGCAAAAACAAATGGACAACCATAGCGAAGACC
AAAAGGTTACTGCTACTGTCAATGATATTGCAGAATCCGTAGAGCGCCTGACTGGTGTCCCAGTGTCCAATATGGGAGCT
AGTGATTTGGAAAGACTCAAAGAAATTAGCAACCGCTTAAAAGAACACGTGATTGGCCAAGATGGAGCTGTTGAAGCTGT
GGCTCGTGCTATTCGCCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCTATCGGTTCCTTCCTCTTTGTTGGACCAA
CAGGTGTCGGTAAGACAGAGTTAGCCAAACAGCTAGCACTGGACCTCTTTGGTTCCAAAGAGGCTATTATTCGACTTGAC
ATGTCCGAATACAGTGATCGTACTGCTGTGTCCAAGTTAATCGGGACAACTGCCGGTTATGTCGGTTATGATGATAATAA
CAATACGTTAACGGAACGAGTTCGTCGCAACCCGTATGCGATTGTTCTATTGGATGAGATTGAAAAAGCCGATCCGCAAG
TCATTACCCTTCTTCTCCAAGTACTGGATGATGGCCGATTAACAGATGGTCAGGGAAATACCATCAACTTTAAAAACACT
GTTATCATTGCTACTTCTAATGCTGGATTTGGGCATCAAGAAGATGAAAATACTGATCAACCTACTATTATGGACCGTAT
TGCGCCTTACTTTAGACCAGAGTTTCTCAATCGTTTCAATGGGGTTATCGAATTCAATCATCTGCAAAAAGAAGACTTAG
AAGAAATTGTTGATTTAATGTTAGCGGAAGTTAATCAAACCATAGCTAAAAAAGGAATCAGCTTAGCTATCTCTGATGAT
GCTAAAGCTCACTTGATTGAATTAGGTTATGACCACGCAATGGGAGTTCGACCATTACGCCGTGTCATCGAGCAAGAAAT
CCGAGACCGCATTACAGACTTTTACCTCGATCACCCAGAGGTCAAAAACTTACAAGCTAGTCTGGAACAAGGACAGTTAG
TCATTCACGACAAAAACTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-679)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)

AAA lid domain (AAA_lid_9)

(259-353)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-600)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

47.391

100

0.481
  clpE Streptococcus mutans UA159

46.544

100

0.472
  clpE Streptococcus pneumoniae TIGR4

48.447

92.132

0.446
  clpE Streptococcus pneumoniae Rx1

48.447

92.132

0.446
  clpE Streptococcus pneumoniae D39

48.447

92.132

0.446
  clpE Streptococcus pneumoniae R6

48.447

92.132

0.446
  clpC Bacillus subtilis subsp. subtilis str. 168

44.341

92.275

0.409
  clpC Streptococcus pneumoniae Rx1

40.943

97.139

0.398
  clpC Streptococcus pneumoniae D39

40.943

97.139

0.398
  clpC Streptococcus pneumoniae TIGR4

40.795

97.139

0.396
  clpC Streptococcus thermophilus LMG 18311

43.065

88.698

0.382
  clpC Streptococcus thermophilus LMD-9

43.065

88.698

0.382
  clpC Streptococcus mutans UA159

42.903

88.698

0.381
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.165

88.555

0.373

Multiple sequence alignment