Detailed information NTG0387693

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: HHJ26_RS15315
• Genome accession: NZ_CP051735
• Coordinates: 3216094..3218916 (-)
• Length: 940 a.a.
• NCBI ID: WP_000357763.1
• Uniprot ID: A0A0H2Z4Q6
• Organism: Escherichia coli strain SCU-108
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3211094..3223916

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHJ26_RS15295 (HHJ26_15300)	-	3212362..3214182 (-)	1821	WP_000704415.1	ATP-binding protein	-
HHJ26_RS15300 (HHJ26_15305)	aphA	3214459..3215172 (+)	714	WP_001226933.1	acid phosphatase AphA	-
HHJ26_RS15305 (HHJ26_15310)	yjbQ	3215283..3215699 (+)	417	WP_000270369.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
HHJ26_RS15310 (HHJ26_15315)	yjbR	3215703..3216059 (+)	357	WP_000155657.1	MmcQ/YjbR family DNA-binding protein	-
HHJ26_RS15315 (HHJ26_15320)	uvrA	3216094..3218916 (-)	2823	WP_000357763.1	excinuclease ABC subunit UvrA	Machinery gene
HHJ26_RS15320 (HHJ26_15325)	ssb	3219170..3219706 (+)	537	WP_000168305.1	single-stranded DNA-binding protein SSB1	Machinery gene
HHJ26_RS15325 (HHJ26_15330)	yjcB	3219805..3220086 (-)	282	WP_001296643.1	YjcB family protein	-
HHJ26_RS15330 (HHJ26_15335)	pdeC	3220515..3222101 (+)	1587	WP_001314348.1	c-di-GMP phosphodiesterase PdeC	-
HHJ26_RS15335 (HHJ26_15340)	soxS	3222104..3222427 (-)	324	WP_000019358.1	superoxide response transcriptional regulator SoxS	-
HHJ26_RS15340 (HHJ26_15345)	soxR	3222513..3222977 (+)	465	WP_000412431.1	redox-sensitive transcriptional activator SoxR	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 103883.54 Da
• Isoelectric Point: 6.6065

>NTDB_id=387693 HHJ26_RS15315 WP_000357763.1 3216094..3218916(-) (uvrA) [Escherichia coli strain SCU-108]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide

• Length: 2823 bp

>NTDB_id=387693 HHJ26_RS15315 WP_000357763.1 3216094..3218916(-) (uvrA) [Escherichia coli strain SCU-108]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTTAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAGAAGCCGGACGTCGACCATATTGAAGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGCTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTCTGCTGTACGCTCGCGTTGGTGAGCCGCGCTGCCCGGACCACGATGTACCGCTGGCGGCGCAAACCGTCAGTC
AGATGGTGGATAACGTGTTGTCCCAGCCGGAAGGCAAGCGTCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAGAACCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAACTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAAGTGCGTGACGATCTTA
CCCAACGTCTTGCCGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTGGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCCGCCAACTTTGCCTGCCCGATTTGCGGTTACAGTATGCGCGAGCTGGAACCTCGCCT
GTTTTCATTTAACAACCCGGCGGGAGCCTGCCCGACCTGTGACGGTCTTGGCGTACAGCAATATTTCGATCCTGACCGCG
TGATCCAGAATCCGGAATTGTCGCTGGCTGGCGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTATTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAACATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGCGCGGTACGTGAAGAATTAGCCAAGTTT
ATCAGCAATCGTCCGTGCGCCAGCTGCGAAGGAACCCGTCTGCGTCGGGAAGCACGCCACGTGTATGTCGAGAATACGCC
GCTGCCCGCCATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGGGCGA
AGATTGCAGAAAAAATCCTTAAAGAGATCGGCGATCGTCTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACACTT
TCCCGCTCAGCAGAGACACTTTCCGGCGGTGAAGCCCAGCGTATTCGTCTGGCGAGCCAGATTGGTGCAGGCCTGGTTGG
CGTGATGTACGTGCTGGATGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGTTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGATCATGTGATCGATATC
GGTCCGGGTGCGGGTGTTCACGGCGGTGAAGTGGTCGCGGAAGGTCCACTGGAAGCGATTATGGCGGTGCCTGAGTCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAGGTGCCGAAGAAACGCGTACCCGCCAATCCAGAAAAAGTGCTGA
AACTGACGGGCGCACGCGGCAACAACCTGAAAGACGTGACGCTGACGCTGCCGGTAGGTCTGTTTACCTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGACTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACACCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGCTATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGACGCTGCGAGGCCTGTCAGGGCGACGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGACATTTACGTACCGTGCGACCAGTGCAAAGGCAAACGCTATAACCGTG
AAACGCTGGAGATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGTTGATGGACGTTGGCCTGACGTACATTCGCCTCGGGCAGTCCGC
AACCACACTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACGCTGT
ATATTCTCGACGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAGCAACTGCTCGACGTACTGCATAAACTGCGCGAT
CAGGGCAATACCATTGTGGTAATTGAGCACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCGGA
AGGCGGCAGTGGGGGCGGCGAAATCCTCGTCTCCGGTACGCCAGAAACCGTCGCAGAGTGCGAAGCTTCGCATACGGCGC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

• UvrA DNA-binding domain (UvrA_DNA-bind) (290-399)

• ABC transporter (ABC_tran) (806-860)

• UvrA interaction domain (UvrA_inter) (130-237)

3D structure

• AlphaFold DB: A0A0H2Z4Q6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.476	100	0.577
uvrA	Streptococcus pneumoniae TIGR4	57.476	100	0.577
uvrA	Streptococcus pneumoniae D39	57.476	100	0.577