Detailed information NTG0387623

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FOB78_RS06740
• Genome accession: NZ_CP044090
• Coordinates: 1310886..1311959 (-)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain FDAARGOS_670
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1305886..1316959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB78_RS06720 (FOB78_06720)	-	1307160..1307675 (-)	516	WP_000919802.1	VanZ family protein	-
FOB78_RS06725 (FOB78_06725)	rlmN	1307675..1308781 (-)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
FOB78_RS06730 (FOB78_06730)	-	1308832..1309410 (-)	579	WP_001224500.1	YutD-like domain-containing protein	-
FOB78_RS06735 (FOB78_06735)	-	1309479..1310811 (-)	1333	Protein_1286	bifunctional metallophosphatase/5'-nucleotidase	-
FOB78_RS06740 (FOB78_06740)	sepM	1310886..1311959 (-)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
FOB78_RS06745 (FOB78_06745)	coaD	1311949..1312434 (-)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
FOB78_RS06750 (FOB78_06750)	-	1312431..1312721 (-)	291	WP_000384889.1	hypothetical protein	-
FOB78_RS06755 (FOB78_06755)	rsmD	1312733..1313272 (-)	540	WP_001266829.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FOB78_RS06765 (FOB78_06765)	-	1313402..1313851 (+)	450	WP_000592263.1	thiol reductase thioredoxin	-
FOB78_RS06770 (FOB78_06770)	asnA	1313896..1314888 (-)	993	WP_000748011.1	aspartate--ammonia ligase	-
FOB78_RS06775 (FOB78_06775)	-	1315002..1316066 (-)	1065	WP_000021302.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=387623 FOB78_RS06740 WP_000796095.1 1310886..1311959(-) (sepM) [Streptococcus agalactiae strain FDAARGOS_670]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=387623 FOB78_RS06740 WP_000796095.1 1310886..1311959(-) (sepM) [Streptococcus agalactiae strain FDAARGOS_670]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658