Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   F1612_RS06640 Genome accession   NZ_CP043843
Coordinates   1289860..1290930 (+) Length   356 a.a.
NCBI ID   WP_158172985.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCCP 16830     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1284860..1295930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1612_RS06610 (F1612_06745) - 1285283..1286746 (+) 1464 WP_158172984.1 rhomboid family protein -
  F1612_RS06615 (F1612_06750) - 1286727..1286930 (+) 204 WP_000087561.1 YqgQ family protein -
  F1612_RS06620 (F1612_06755) - 1286927..1287913 (+) 987 WP_000161314.1 ROK family glucokinase -
  F1612_RS06625 (F1612_06760) - 1287913..1288242 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  F1612_RS06630 (F1612_06765) - 1288239..1288862 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  F1612_RS06635 (F1612_06770) comGA 1288914..1289888 (+) 975 WP_000697227.1 competence type IV pilus ATPase ComGA Machinery gene
  F1612_RS06640 (F1612_06775) comGB 1289860..1290930 (+) 1071 WP_158172985.1 competence type IV pilus assembly protein ComGB Machinery gene
  F1612_RS06645 (F1612_06780) comGC 1290944..1291255 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  F1612_RS06650 (F1612_06785) comGD 1291233..1291679 (+) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  F1612_RS06655 (F1612_06790) comGE 1291666..1291965 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  F1612_RS06660 (F1612_06795) comGF 1291883..1292380 (+) 498 WP_001829055.1 competence type IV pilus minor pilin ComGF Machinery gene
  F1612_RS06665 (F1612_06800) - 1292477..1292623 (+) 147 WP_001789879.1 hypothetical protein -
  F1612_RS06670 (F1612_06805) - 1292613..1293137 (+) 525 WP_001015123.1 shikimate kinase -
  F1612_RS06675 (F1612_06810) gcvT 1293296..1294387 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  F1612_RS06680 (F1612_06815) gcvPA 1294407..1295753 (+) 1347 WP_043854778.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41377.75 Da        Isoelectric Point: 10.0606

>NTDB_id=386167 F1612_RS06640 WP_158172985.1 1289860..1290930(+) (comGB) [Staphylococcus aureus strain NCCP 16830]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMAYKNKQLGATILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDSFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=386167 F1612_RS06640 WP_158172985.1 1289860..1290930(+) (comGB) [Staphylococcus aureus strain NCCP 16830]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGGCATATA
AAAATAAGCAATTAGGTGCCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAGATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGTAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATTTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCC
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATTCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCGCAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

99.157

100

0.992
  comGB Staphylococcus aureus N315

99.157

100

0.992

Multiple sequence alignment