Detailed information NTG0386154

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: F1612_RS04715
• Genome accession: NZ_CP043843
• Coordinates: 926103..927146 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NCCP 16830
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 921103..932146

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F1612_RS04685 (F1612_04785)	-	921530..921640 (+)	111	WP_001790257.1	hypothetical protein	-
F1612_RS04690 (F1612_04790)	-	921669..922082 (+)	414	WP_001566709.1	hypothetical protein	-
F1612_RS04695 (F1612_04795)	-	922513..923499 (-)	987	WP_000999713.1	FUSC family protein	-
F1612_RS04700 (F1612_04800)	map	924029..924787 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
F1612_RS04705 (F1612_04805)	-	925004..925390 (+)	387	WP_001110179.1	hypothetical protein	-
F1612_RS04710 (F1612_04810)	liaF	925405..926106 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
F1612_RS04715 (F1612_04815)	vraS	926103..927146 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
F1612_RS04720 (F1612_04820)	vraR	927136..927765 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
F1612_RS04725 (F1612_04825)	-	927877..929094 (-)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
F1612_RS04730 (F1612_04830)	-	929372..929647 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
F1612_RS04735 (F1612_04835)	-	929654..930118 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
F1612_RS04740 (F1612_04840)	-	930265..930465 (+)	201	WP_000180460.1	DUF1128 family protein	-
F1612_RS04745 (F1612_04845)	-	930468..931724 (+)	1257	WP_078103502.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=386154 F1612_RS04715 WP_001017131.1 926103..927146(+) (vraS) [Staphylococcus aureus strain NCCP 16830]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=386154 F1612_RS04715 WP_001017131.1 926103..927146(+) (vraS) [Staphylococcus aureus strain NCCP 16830]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACTCAAATATTTGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1