Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   HHM65_RS10435 Genome accession   NZ_CP051624
Coordinates   2103191..2105173 (-) Length   660 a.a.
NCBI ID   WP_015058135.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2098191..2110173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM65_RS10410 (HHM65_10415) cinA 2099032..2100303 (-) 1272 WP_015058134.1 competence/damage-inducible protein A Machinery gene
  HHM65_RS10415 (HHM65_10420) - 2100427..2100780 (-) 354 WP_003058738.1 VOC family protein -
  HHM65_RS10420 (HHM65_10425) - 2100783..2101355 (-) 573 WP_003058799.1 DNA-3-methyladenine glycosylase I -
  HHM65_RS10425 (HHM65_10430) ruvA 2101365..2101958 (-) 594 WP_003058778.1 Holliday junction branch migration protein RuvA Machinery gene
  HHM65_RS10430 (HHM65_10435) - 2101960..2103180 (-) 1221 WP_014612636.1 MFS transporter -
  HHM65_RS10435 (HHM65_10440) hexB 2103191..2105173 (-) 1983 WP_015058135.1 DNA mismatch repair endonuclease MutL Machinery gene
  HHM65_RS10440 (HHM65_10445) hexA 2105301..2107856 (-) 2556 WP_015058136.1 DNA mismatch repair protein MutS Machinery gene
  HHM65_RS10445 (HHM65_10450) - 2107843..2108196 (-) 354 WP_015058137.1 YlbF family regulator -
  HHM65_RS10450 (HHM65_10455) argR 2108193..2108630 (-) 438 WP_003055516.1 arginine repressor -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74524.94 Da        Isoelectric Point: 5.5692

>NTDB_id=385964 HHM65_RS10435 WP_015058135.1 2103191..2105173(-) (hexB) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQVTIDIEESGLKKIQITDNGEGMSPEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEDNHGSLLVAIGGEIETLEETSTPVGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVSFILISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISNADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSKGLYYDPQRNDFFVKESDVSEKIPESNFHNTEIDKTVKDQR
TKQFPDLGENTGFSSVKRASRSQDEITDADHPGLDLKNKQKLSQMLTRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=385964 HHM65_RS10435 WP_015058135.1 2103191..2105173(-) (hexB) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A74]
ATGACAAACATTATTGAATTACCAGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATCGATGCTAAGAGTAGCCAAGTCACCATTGATATTGAAGAGTCTGGTCTCAAAA
AGATACAGATTACGGACAATGGTGAAGGGATGTCGCCTGAAGACCTTCCTTTGAGTTTGCGGCGACATGCTACCAGTAAA
ATAAAAAGTCAAAGTGATCTCTTTCGAATTAGAACACTTGGTTTTAGGGGAGAAGCCTTACCATCGGTTGCTTCTATCAG
TAAAATCACAATAAAAACAGCTACTAAGGAAGATAATCACGGTTCTCTTTTAGTTGCTATCGGCGGAGAGATTGAAACGC
TCGAGGAAACGTCGACGCCTGTAGGTACCAAGATTAAGGTTGAAAACCTTTTTTATAACACGCCTGCTCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAGTTAGCCCATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCAGAAGTTTCTTT
CATCCTTATTAGTGATGGCCGTCAATTAACTCAGACATCAGGGACGGGGGACCTGCGGCAGGCTATTGCAGGGATTTATG
GCTTGAATACTGCCAAAAAAATGATTGCTATTTCCAATGCCGATTTGGACTTTGAAGTGTCGGGCTATGTCAGTTTACCA
GAGTTGACACGCGCCAACCGCAATTATATGACCATTTTAATCAATGGACGCTACATTAAAAATTTCTTGCTCAATCGGGC
TATTTTAGATGGTTACGGCTCTAAGTTGATGGTTGGACGTTTCCCAATTGTGGTGATTGATATTCAGATTGACCCCTATT
TGGCCGATGTCAATGTTCACCCTACTAAGCAAGAGGTCCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATTAGTACG
GCGATTTCTGAAAGTCTTAAGGAGCAAGATTTGATTCCAGATGCTCTGGAGAACTTAGCTAAATCAAGCACACGACACTT
TTCTAAACCAGAGCAAACACAACTTCCATTACAATCTAAAGGGCTTTATTATGATCCTCAAAGAAATGACTTTTTTGTTA
AAGAATCGGATGTTTCTGAAAAAATACCTGAGAGTAATTTTCATAATACAGAGATTGACAAGACTGTAAAGGATCAAAGG
ACGAAGCAGTTTCCTGATTTAGGAGAGAATACAGGATTTTCCTCAGTAAAACGTGCTAGTCGATCACAGGATGAGATAAC
TGATGCTGATCACCCTGGACTTGATTTGAAAAACAAACAGAAATTATCTCAAATGCTAACCCGTTTGGAAAATGAAGAGC
AATCAGTATTTCCCGAATTGGATTATTTTGGTCAGATGCACGGAACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATAGGTGAGGTTGACAGTAGTTT
ACAGCAGCTGTTGGTGCCCTATTTGTTTGAGTTTTCCGGCTCGGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGTATCTTCCTAGAAGTTTATGGGCACAATACTTTCATTTTGAGAGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTCTCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTAC
TGCAATTAGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTGTTGATTAATTTCAGTAAGGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCACACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(462-604)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.012

100

0.689