Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   F0T12_RS10265 Genome accession   NZ_CP043812
Coordinates   1975052..1978201 (-) Length   1049 a.a.
NCBI ID   WP_164824782.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain NG290     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1970052..1983201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F0T12_RS10255 (F0T12_11460) - 1970136..1971362 (+) 1227 WP_003697786.1 PilT/PilU family type 4a pilus ATPase -
  F0T12_RS10260 (F0T12_11465) yccS 1971479..1973629 (+) 2151 WP_003690198.1 YccS family putative transporter -
  F0T12_RS10265 (F0T12_11470) pilC 1975052..1978201 (-) 3150 WP_164824782.1 PilC family type IV pilus tip adhesin Machinery gene
  F0T12_RS10270 (F0T12_11480) - 1978889..1979152 (+) 264 WP_017147189.1 hypothetical protein -
  F0T12_RS10275 (F0T12_11485) gnd 1979232..1980680 (+) 1449 WP_003688061.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  F0T12_RS10280 (F0T12_11490) waaA 1980743..1982014 (+) 1272 WP_025455875.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  F0T12_RS10285 (F0T12_11495) - 1982055..1982504 (+) 450 WP_003688065.1 CopD family copper resistance protein -

Sequence

Protein


Download         Length: 1049 a.a.        Molecular weight: 115286.57 Da        Isoelectric Point: 9.7697

>NTDB_id=385933 F0T12_RS10265 WP_164824782.1 1975052..1978201(-) (pilC) [Neisseria gonorrhoeae strain NG290]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGAMAQTHQYAIIMNERKQPEVKWKDQYNQSALKDKSRERTFSHTSQKNSLG
ITSNFISFNNNDELVSQQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIHTTRPGLAGYGYTGIRCGSTKDCPKL
TYKTRFSFDNPDLLKTRGGLDRHTEPSRENSPIYKLKDYPWLGVSFNLGGEGTAKDGRSSSKLVSSFDENNSNSNQNLVY
TTEDHRISLSNWQQETTAMAYYLNAKLHLLDKKGIKDITGKTVRLGVLKPSIDVKTQNTGLSGILNFWSKWDIKDNGQIP
VKLGLPEVKAGRCINEPNPNKNTQAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTRTDPARPGRH
SLAALDTQNIKSREPNFNSRQTVIRLPGGVYRIAPTRDRIVGLNGNDGKNDIFGIYKDRLVTPEVDEWAKVLLPWTVRYY
GNDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATSANDGMVHIFKKTGTDQRGYE
LKLSYIPGTMERKDIEGNDSDLAKELRAFAEQGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTK
IDSNPVGVSMFDVKNGDNNGKNRVKVELGYTVGTPQIGKTRNGTYSAFLASGYAAKDIGSGDNKTALYVYDLENGSGSLI
KKIEVKDGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSDSNPDKWSVSTIFEGGKPITSAPAVSRLADKRVVIF
GTGSDLSESDVFNTDEQYIYGIFDDDKGTVKVTVQNGTGGGLLEQTLTKENNTLFLSNNKASGGSNGKGWVVRLREGERV
TVKPTVVLRTAFVTIRSYTGMDKCGAQTAILGINTADGGALTPRSARPIVPDHNSVAQYSGHKKTTDGKSVPIGCMWKNS
KTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIK
RLSWREVFF

Nucleotide


Download         Length: 3150 bp        

>NTDB_id=385933 F0T12_RS10265 WP_164824782.1 1975052..1978201(-) (pilC) [Neisseria gonorrhoeae strain NG290]
ATGAATAAAACTTTGAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCCATCAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGAAGG
ATCAATATAATCAATCAGCATTAAAGGACAAAAGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAAACAGCCTCGGC
ATCACAAGCAATTTTATCTCATTCAACAATAACGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGC
CACCTACCTGCCGCCCTACGGCAAGGTTTCCGGCTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATTGGA
TTCATACCACCCGGCCCGGGCTGGCAGGCTACGGCTACACCGGTATCCGTTGCGGAAGTACCAAAGACTGTCCCAAACTT
ACCTATAAAACCCGATTTTCCTTCGATAATCCCGACTTGCTAAAAACAAGAGGCGGGCTGGATAGGCACACAGAGCCAAG
CCGCGAAAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGTGTGTCTTTCAATTTGGGCGGCGAGGGTACCG
CCAAAGATGGCAGATCATCCAGCAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTCTAT
ACGACAGAAGACCACCGTATTTCCCTTAGCAACTGGCAGCAAGAAACGACCGCCATGGCCTATTATCTGAACGCCAAGCT
GCACCTGCTGGACAAAAAAGGGATTAAAGATATCACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATG
TGAAGACACAAAATACGGGGCTTAGCGGCATTCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCG
GTCAAGCTCGGCCTGCCGGAAGTCAAAGCAGGCCGCTGCATCAACGAACCGAACCCCAATAAGAATACCCAAGCCCCTTC
GCCGGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCCA
CCTACCCCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCGAACCGACCCCGCCCGGCCCGGCCGGCAT
TCCCTCGCCGCTTTGGATACGCAGAACATCAAAAGCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCGATTGCC
GGGCGGCGTGTACCGGATCGCCCCGACTCGCGACAGGATCGTGGGTTTGAATGGCAATGACGGCAAAAACGACATTTTCG
GCATCTACAAGGACAGGCTCGTCACACCTGAGGTCGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTAC
GGTAATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATA
CCGCATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGCGGTCG
GCGGGTATCTGGCAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAAAAACCGGCACAGACCAACGAGGCTACGAA
CTGAAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGCAATGACTCCGACCTCGCCAAAGAGCTGCG
CGCCTTTGCCGAACAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACC
AAGACAAGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTGGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAA
ATCGACAGCAACCCGGTCGGCGTTTCCATGTTTGATGTCAAAAATGGCGATAATAACGGCAAAAATCGCGTGAAAGTGGA
ATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCGCAACGGCACATACTCCGCCTTCCTCGCCTCCGGTTATG
CGGCTAAAGATATTGGCAGCGGCGATAATAAAACCGCGCTGTATGTATATGATTTGGAAAACGGCAGTGGTAGTCTGATT
AAAAAAATCGAAGTGAAGGACGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGA
TATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCGATTCCAATCCTGATAAATGGTCTGTAA
GCACTATTTTCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTCGTTATCTTC
GGTACGGGCAGCGATTTGAGTGAAAGTGACGTATTCAATACGGACGAACAATATATTTACGGTATCTTTGACGACGATAA
GGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGTTGCTCGAGCAAACGCTTACGAAGGAAAATAACACCT
TGTTCCTGAGCAATAATAAGGCATCCGGCGGATCGAACGGCAAAGGGTGGGTAGTGAGATTGAGGGAAGGAGAACGCGTT
ACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTCACCATCCGCAGCTATACGGGCATGGACAAATGTGGCGCGCA
AACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATCACA
ATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCACCGACGGCAAGTCCGTCCCCATAGGCTGTATGTGGAAAAACAGC
AAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGATTT
CCCCGTCACGGCAGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAGGCGTCCCGGCAAAAACAACCGCTGCT
TCTCCAAAAAAGGGGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAA
CGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(522-860)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

70.227

100

0.708

Multiple sequence alignment